{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:08:27Z","timestamp":1759018107770,"version":"3.44.0"},"reference-count":0,"publisher":"ALUNA","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: The impacts of zinc oxide nano-extract from Origanum majorana leaves on the liver histological morphology of rats were investigated in the current study.\nMaterials and Methods: There were forty-two rats that are rats are divided into six groups of seven animals. Performing the experiment, 0.5 mg of normal saline\nwas given to the first group, T1. Additionally, a 10 mg\/kg nano-extract of Origanum majorana leaves was given to the second group, T2. A nano-extract solution\ncontaining 15 mg\/kg of Origanum majorana leaves extract was injected to the third group, T3. A nano-extract derived from the seeds of Origanum majorana\nleaves of 10 mg\/kg in combination with L. donovania was injected to the fourth group, T4. A nano-extract from Origanum majorana leaves at a concentration\nof 15 mg\/kg in conjunction with L. donovania was injected to the fifth group, T5. Finally, L. donovania alone was injected for 29 days to the sixth group, T6.\nResults: Considerable changes were noticed in the nucleus and fib. Moreover, the findings revealed that there are several changes in their liver\u2019s structure\nlike sinusoidal dilatation, prescience of specific inflammatory cells surrounding the central vein, and prescience of simple necrosis and bleeding in L. dono\nvani-\ninfected tissue.\nConclusions: The histological changes on the liver treated with Nano-extract (zinc oxide) of the Origanum majorana leaves at different concentrations was\nemployed for treating the histological shifts and reducing the damage caused by the parasite. Thus, effectiveness of the nano-extract is effective in reducing\nthe influences and resisting the parasite.<\/jats:p>","DOI":"10.36740\/wlek\/208460","type":"journal-article","created":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T18:13:10Z","timestamp":1758996790000},"page":"1602-1608","source":"Crossref","is-referenced-by-count":0,"title":["Investigating the impact of zinc oxide nanoparticles derived from the alcoholic extract of Origanum majorana leaves on the histological morphology of Leishmania donovania infected albino rats' livers"],"prefix":"10.36740","author":[{"given":"Sukayna Jabbar","family":"Mushattat","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jabbar Abadi","family":"AlAridi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Salim","family":"Kadhim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2025,8,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-208460-129154","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-208460-129154","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T18:13:14Z","timestamp":1758996794000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Investigating-the-impact-of-zinc-oxide-nanoparticles-derived-from-the-alcoholic-extract,208460,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,30]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025]]}},"alternative-id":["208460"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/208460","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,30]]}}}