{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T10:40:13Z","timestamp":1756118413280,"version":"3.44.0"},"reference-count":0,"publisher":"ALUNA","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: to\nconduct a morphological evaluation of the effectiveness of probiotic disinfectants for abdominal cavity sanitation in experimental widespread peritonitis.\nMaterials and Methods: The experimental study was conducted on 45 white male Wistar rats aged 4-5 months, which were modelled with peritonitis. The\nrats were divided into 3 groups of 15 animals each. The treatment of animals in the main group (group I) consisted of washing the abdominal cavity with a\n5% solution of probiotic disinfectant, applying a probiotic disinfectant spray and a gel with probiotics to the surgical wound. For the treatment of rats in the\ncomparison group (group II), a sorbent solution was used. The treatment of rats in the placebo control group (group III) consisted of abdominal lavage with\n0.9% NaCl. Histological, histochemical and immunohistochemical studies were performed.\nResults: In the main group, 10 (66.7 %) rats survived, in which peritonitis was eliminated, as evidenced by clinical and morphological results. In the comparison\ngroup, 8 (53.3 %) rats survived, in which peritonitis was eliminated. All animals in the placebo control group died of severe peritonitis. The best repair and\nrenewal of mesothelial cells with a pronounced intensity of parietal peritoneal expression was in group I. In group II on the 7th day there were mesothelial\ncells with moderate expression, in group III - there was a weak intensity of expression in single cells.\nConclusions: According to our data, probiotic disinfectants are effective for abdominal cavity sanitation in peritonitis, which was proved by experimental study.<\/jats:p>","DOI":"10.36740\/wlek\/208992","type":"journal-article","created":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T09:59:06Z","timestamp":1756115946000},"page":"1319-1326","source":"Crossref","is-referenced-by-count":0,"title":["Morphological evaluation of the effectiveness of probiotic\ndisinfectants in the treatment of experimental widespread\nperitonitis"],"prefix":"10.36740","author":[{"given":"Olga O.","family":"Bilyayeva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ivan V.","family":"Karol","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Olena O.","family":"Dyadyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2025,7,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-208992-128060","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-208992-128060","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,25]],"date-time":"2025-08-25T09:59:11Z","timestamp":1756115951000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Morphological-evaluation-of-the-effectiveness-of-probiotic-ndisinfectants-in-the,208992,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,7,30]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2025]]}},"alternative-id":["208992"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/208992","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,7,30]]}}}