{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,28]],"date-time":"2025-09-28T00:08:33Z","timestamp":1759018113216,"version":"3.44.0"},"reference-count":0,"publisher":"ALUNA","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: To determine the peculiarities of changes in the levels of B vitamins and their dependence on body mass index (BMI) in patients with GERD and metabolic\ndysfunction-associated fatty liver disease (MDAFLD).\nMaterials and Methods: 112 patients with GERD were examined. Patients were divided into two groups. Group 1 included 50 patients with GERD, and group\n2 consisted of 62 patients with GERD in combination with MDAFLD. The level of homocysteine and B vitamins in the blood serum was determined.\nResults: At patients group 1 were diagnosed the decreased levels of B6 and B12 in blood serum against a background of a slight increase in homocysteine\nlevels in blood serum (up to 17.9\u00b10.7 umol\/l \u2013 p&lt;0.05). In patients in group 2, a significant decrease in all B vitamins examined in the blood serum was found,\naccompanied by a significant increase in homocysteine levels (2.4 times \u2013 p&lt;0.01).\nConclusions: In the vast majority of patients with GERD and MDAFLD, an increase in BMI was found, namely, overweight in 25.8% (p &lt; 0.01) of patients and\ngrade I obesity (in 37.1% of patients \u2013 p &lt; 0.001). In patients with GERD and MDAFLD, a significant decrease in serum levels of B vitamins (B1, B3, B6, B9,\nB12) was found, which correlates negatively with overweight and obesity in these patients.<\/jats:p>","DOI":"10.36740\/wlek\/209518","type":"journal-article","created":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T18:13:10Z","timestamp":1758996790000},"page":"1635-1640","source":"Crossref","is-referenced-by-count":0,"title":["Peculiarities of changes in the level of vitamins b in patients with gastroesophageal reflux disease metabolic-associated fatty liver disease"],"prefix":"10.36740","author":[{"given":"Yelyzaveta S.","family":"Sirchak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bohdana V.","family":"Bezushko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mykhailo M.","family":"Havrylec","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktoria M.","family":"Hadzheha","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Habriella E.","family":"Reyti","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yurii P.","family":"Balazh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oleksandr M.","family":"Kochmar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2025,8,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-209518-129158","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-209518-129158","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,27]],"date-time":"2025-09-27T18:13:15Z","timestamp":1758996795000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Peculiarities-of-changes-in-the-level-of-vitamins-b-in-patients-with-gastroesophageal,209518,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,30]]},"references-count":0,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025]]}},"alternative-id":["209518"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/209518","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,30]]}}}