{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T07:21:19Z","timestamp":1769844079740,"version":"3.49.0"},"reference-count":0,"publisher":"ALUNA","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: To reveal the applicability of lectin histochemistry methods for the evaluation of bone tissue injury recovery.\nMaterials and Methods: The research was accomplished on 35 mature rabbits aged 6-7 months weighting 2.5-3 kg subdivided into three groups. Control\ngroup included 10 rabbits with post traumatic mandibular bone injury site healed under the blood cloth. First experimental group consisted of animals with\ndamaged bone recovery supplemented with an osteotropic material based on native octacalcium phosphate (OCP-N). Second experimental group consisted\nof rabbits with bone defect filled with natural collagen cone (Col-C). Monitoring of the post-traumatic processing. was carried out for 84 days using panel of\nthree lectins (WGA, LABA and CNFA) with different carbohydrate specificities\nResults: The lectins demonstrated high variability of binding with constituents of posttraumatic bone tissue. In particular, it was revealed rather selective WGA\nreactivity with microvascular endothelium, LABA reactivity with macrophages and CNFA with fibroblaststs and osteogenic cells. Injured bone in control and\nboth experimental groups demonstrated distinct rearrangement of lectin receptor sites with drift towards posttraumatic recovery being more prominent after\naplication of OCP-N osteotropic material. Traumatic bone injury induced accumulation of macrophages in the site of inflammation, as well as redistribution\nof lectin receptors in microvascular endothelium.\nConclusions: Lectins of different carbohydrate specificities can be recommended for monitoring bone tissue regeneration after posttraumatic injuries.<\/jats:p>","DOI":"10.36740\/wlek\/215798","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T16:53:47Z","timestamp":1769792027000},"page":"2594-2603","source":"Crossref","is-referenced-by-count":0,"title":["Lectin histochemistry of bone regeneration dynamics in the rabbit mandible following transplantation of natural mineral and organic osteoplastic materials"],"prefix":"10.36740","author":[{"given":"Ilona V.","family":"Chelpanova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander D.","family":"Lutsyk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Antonina M.","family":"Yashchenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yevgen V.","family":"Paltov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khrystyna I.","family":"Strus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iryna I.","family":"Savka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2025,12,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-215798-135302","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-215798-135302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T16:53:49Z","timestamp":1769792029000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Lectin-histochemistry-of-bone-regeneration-dynamics-in-the-rabbit-mandible-following,215798,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,30]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025]]}},"alternative-id":["215798"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/215798","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,30]]}}}