{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,31]],"date-time":"2026-01-31T07:42:28Z","timestamp":1769845348854,"version":"3.49.0"},"reference-count":0,"publisher":"ALUNA","issue":"12","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: To provide a quantitative assessment of the clinical effectiveness of the high-energy Nd:YAG laser therapy versa traditional pharmacotherapy in patients\nwith papulopustular rosacea.\nMaterials and Methods: The study included 40 patients with clinically diagnosed papulopustular rosacea. Participants were divided into two subgroups:\none received standard pharmacotherapy with systemic retinoids, and the other underwent fractional Nd:YAG 1064 nm laser treatment. Clinical outcomes were\nassessed using digital image analysis (ImageJ software), with erythema quantified in pixel units and relative facial area involvement. Statistical evaluation\nwas performed with Student\u2019s t-test, considering p &lt; 0.05 as significant\nResults: Both treatment modalities demonstrated clinical improvement; however, outcomes were more pronounced in the laser-treated group. Traditional\npharmacotherapy achieved a 22% reduction in erythema area, while Nd:YAG laser therapy resulted in a 79% reduction. The proportion of erythematous facial area\ndecreased from 24.4% to 16.7% in the pharmacotherapy group and from 27.6% to 5.7% in the laser group. No systemic or local adverse effects were reported.\nConclusions: Nd:YAG FRAC3\u00ae laser therapy demonstrated superior efficacy over pharmacotherapy in reducing erythema and inflammatory manifestations in\npapulopustular rosacea. These findings support its role as an effective and safe alternative or adjunct to standard pharmacological management.<\/jats:p>","DOI":"10.36740\/wlek\/215804","type":"journal-article","created":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T16:53:47Z","timestamp":1769792027000},"page":"2642-2647","source":"Crossref","is-referenced-by-count":0,"title":["High-energy Nd: YAG laser therapy for papulopustular rosacea: Quantitative assessment with digital image processing"],"prefix":"10.36740","author":[{"given":"Vladyslav","family":"Smiianov","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asiri Sultan","family":"Zuhair Ali","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Kaldiaieva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oksana","family":"Melekhovets","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yevhen","family":"Smiianov","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ihor","family":"Hushchuk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2025,12,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-215804-135308","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-215804-135308","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,30]],"date-time":"2026-01-30T16:53:51Z","timestamp":1769792031000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/High-energy-Nd-YAG-laser-therapy-for-papulopustular-rosacea-Quantitative-assessment,215804,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,30]]},"references-count":0,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025]]}},"alternative-id":["215804"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/215804","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,30]]}}}