{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T11:13:25Z","timestamp":1775733205491,"version":"3.50.1"},"reference-count":0,"publisher":"ALUNA","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"\n Aim<\/jats:title>\n This study aimed to find out predictors of chronic liver disease (CLD) in adults and evaluate key determinants that may influence healthy aging.<\/jats:p>\n <\/jats:sec>\n \n Material and methods<\/jats:title>\n A case-control study was conducted among adults who were receiving care at a tertiary care center. Demographics, lifestyle factors, and clinical variables like BMI were collected. Statistical analysis was performed using chi-square testing for association and logistic regression analysis to identify independent factors that predict CLD, p-value of <0.05 was used to identify significance for all information collected.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Significant links were found between CLD and several factors. Males were significantly more affected with CLD (78.5%, p < 0.001), making gender one of the factors that predict CLD. Similarly, age was a significant factor, with those aged 40-60 being the most affected (33%, p = 0.039). Abnormal BMI was strongly associated with CLD, found in 84.6% cases (p = 0.008). Alcohol consumption demonstrated a marked association with chronic liver disease (p < 0.001), with former and current alcohol use substantially more common among cases. After logistics regression analysis, male gender, abnormal BMI, and alcohol consumption are significant independent predictors of CLD.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n The study highlights gender (male), age (40-60), abnormal BMI and alcohol consumption as significant predictors of CLD in the studied population. These findings emphasize the urgent need for targeted screening and lifestyle-based preventive interventions, particularly focusing on metabolic health and weight management, to mitigate the rising burden of liver disease and promote healthy aging.<\/jats:p>\n <\/jats:sec>","DOI":"10.36740\/wlek\/218230","type":"journal-article","created":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T10:29:38Z","timestamp":1775730578000},"page":"491-499","source":"Crossref","is-referenced-by-count":0,"title":["Potential Predictors of Chronic Liver Disease among Adults: Key Determinants For Promoting Healthy Aging"],"prefix":"10.36740","author":[{"ORCID":"https:\/\/orcid.org\/0009-0002-8158-8135","authenticated-orcid":false,"given":"Mohammed","family":"Isham Shiju","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-7955-7943","authenticated-orcid":false,"given":"Benzil","family":"Binu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4455-9872","authenticated-orcid":false,"given":"Aadith","family":"Soorya Arun Kumar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-4914-4120","authenticated-orcid":false,"given":"Jessica","family":"James Stanley","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0003-2727-2145","authenticated-orcid":false,"given":"Abhinandh","family":"Uthaman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0000-8004-7308","authenticated-orcid":false,"given":"Abrar","family":"Allahyari","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7028-4529","authenticated-orcid":false,"given":"Tatjana","family":"Ille","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0007-9263-2337","authenticated-orcid":false,"given":"Abdulsalam","family":"Al Mujamee","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0006-4528-6921","authenticated-orcid":false,"given":"Mohammed","family":"Ahmed Elshobary","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-5989-8084","authenticated-orcid":false,"given":"Sneha","family":"Reji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2026,3,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-218230-138290","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-218230-138290","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,9]],"date-time":"2026-04-09T10:29:40Z","timestamp":1775730580000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Potential-Predictors-of-Chronic-Liver-Disease-among-Adults-Key-Determinants-For-Promoting,218230,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,30]]},"references-count":0,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2026]]}},"alternative-id":["218230"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/218230","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,30]]}}}