{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:06:52Z","timestamp":1789553212140,"version":"build-2803163510"},"reference-count":0,"publisher":"ALUNA","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: To study biochemical markers of brain tissue damage, the levels of which could be used to assess the degree of damage to the nervous tissue and predict\nthe course and outcome of the disease.\nMaterials and Methods: There were 38 patients in the acute period and 33 in the remote period of MBT were examined. The patients\u2019 complaints, levels of\nbrain-specific proteins S-100\u03b2, BDNF and inflammatory biomarkers such as interleukins IL-8 and IL-10 were studied in detail.\nResults: The study of complaints showed their similarity in both the acute and remote periods, apart from an increase in the number of patients with\nmeteorological sensitivity. An increase in S-100\u03b2 levels and a decrease in BDNF levels indicate a slowdown in the rate of recovery processes in this category of\npatients and a deterioration in brain plasticity processes. An increase in IL-8 and IL-10 levels indicates further progression of the disease.\nConclusions: The study of these biomarkers contributes to the prognosis and course of the consequences of mine-blast trauma and the choice of therapeutic\nagents in treatment.<\/jats:p>","DOI":"10.36740\/wlek\/225980","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:39:33Z","timestamp":1789551573000},"page":"1475-1479","source":"Crossref","is-referenced-by-count":0,"title":["Clinical-and-neurological symptoms and dynamics of certain biomarkers in the acute and remote periods of combat traumatic brain injury"],"prefix":"10.36740","author":[{"given":"Volodymyr O.","family":"Korshniak","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oleksandr R.","family":"Pulyk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mykola F.","family":"Posokhov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pawlo M.","family":"Posokhov","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22436","published-online":{"date-parts":[[2026,7,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-225980-145204","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-225980-145204","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:39:34Z","timestamp":1789551574000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Clinical-and-neurological-symptoms-and-dynamics-of-certain-biomarkers-in-the-acute,225980,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,30]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026]]}},"alternative-id":["225980"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/225980","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,30]]}}}