{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T10:06:53Z","timestamp":1789553213223,"version":"build-2803163510"},"reference-count":0,"publisher":"ALUNA","issue":"7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiadomo\u015bci Lekarskie"],"abstract":"<jats:p>Aim: To investigate histological, ultrastructural, and morphometric changes in the wall of arterial vessels, glomerular and peritubular capillaries, and convoluted\ntubules of the kidney under the influence of a cold factor in an experiment.\nMaterials and Methods: The experiment was conducted on 80 mature white Wistar male rats, 10 of which served as controls. Animals were divided into 7\ngroups of 10 animals each according to experimental time points: at the peak of cooling and at 1, 3, 7, 14, 21, and 30 days of the recovery period. All procedures\nwith animals were performed according to bioethical standards. Experimental-morphological analysis was conducted using histological, electron microscopic,\nand morphometric research methods.\nResults: It was established that hypothermia causes vasoconstriction of the kidney\u2019s arterial vessels. From day 1 of the post-hypothermic period, edematous\nchanges develop, which increase maximally by day 3 and persist through day 7 of the experiment. Starting from day 14, edematous changes decrease and\nstructural organization of kidney parenchyma is restored. Reparative processes are completed by day 30.\nConclusion: Profound renal hypothermia causes a complex process: early vascular spasm leading to ischemia, subsequent inflammatory enhancement of\ndamage with maximum effect at days 3-7, followed predominantly by reversible recovery with isolated foci of irreversible remodeling.<\/jats:p>","DOI":"10.36740\/wlek\/225986","type":"journal-article","created":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:39:33Z","timestamp":1789551573000},"page":"1625-1632","source":"Crossref","is-referenced-by-count":0,"title":["Structural characteristics of the kidney in conditions of\nexperimental hypothermia"],"prefix":"10.36740","author":[{"given":"Vasyl M.","family":"Pertsovych","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oksana H.","family":"Popadynets","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vasyl M.","family":"Ivanochko","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Halyna Yu.","family":"Yurakh","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Romaniia R.","family":"Barchuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ivan O.","family":"Mykhailiuk","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22436","published-online":{"date-parts":[[2026,7,30]]},"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"link":[{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-225986-145231","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/pdf-225986-145231","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T09:39:40Z","timestamp":1789551580000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wiadomoscilekarskie.pl\/Structural-characteristics-of-the-kidney-in-conditions-of-nexperimental-hypothermia,225986,0,2.html"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,30]]},"references-count":0,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2026]]}},"alternative-id":["225986"],"URL":"https:\/\/doi.org\/10.36740\/wlek\/225986","relation":{},"ISSN":["0043-5147","2719-342X"],"issn-type":[{"value":"0043-5147","type":"print"},{"value":"2719-342X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,30]]}}}