{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,7,8]],"date-time":"2022-07-08T22:59:40Z","timestamp":1657321180200},"reference-count":20,"publisher":"ALUNA","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiad Lek"],"published-print":{"date-parts":[[2022,5]]},"abstract":"<jats:p>The aim: The goal of this study was to assess the immune response to the HB vaccine (the level of anti-HBs titer), as well as the prevalence of serum creatinine, urea, CRP, and serum albumin levels, and the relationship between these and immune response to the vaccine. \nMaterials and methods: 127 patients with chronic renal disease on hemodialysis (HD) were compared to 40 healthy people in Iraqi dialysis center, Baghdad. Antibodies to the hepatitis B core antigen (anti\u2013HBc) were detected using the ARCHITECT SYSTEM and the Anti-HBs titer, HBs Ag, Anti-HCV determined by ELISA. \nResults: When compared to the poor and non-responder groups, the mean value of anti-HBs titer increased considerably in the good responder group. The good responder and control groups, on the other hand, showed no significant changes. The anti-HBs titer was found to have the strongest negative correlation with serum creatinine, blood urea, and C-reactive protein levels. There was a considerable positive connection between anti-HBs titer and albumin levels. \nConclusions: The responses of HD patients to the HB vaccine revealed the significant negative relation between serum creatinine, blood urea levels, and CRP, as well as a significant positive correlation between serum albumin.<\/jats:p>","DOI":"10.36740\/wlek202205209","type":"journal-article","created":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T15:37:19Z","timestamp":1656344239000},"page":"1284-1288","source":"Crossref","is-referenced-by-count":0,"title":["EVALUATION OF SOME BIOCHEMICAL MARKERS AND THE ANTIBODY RESPONSE TO HEPATITIS B VACCINE IN HEMODIALYSIS PATIENTS"],"prefix":"10.36740","volume":"75","author":[{"given":"Sally B.","family":"Shabeeb","sequence":"first","affiliation":[{"name":"UNIVERSITY OF BAGHDAD, BAGHDAD, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaima R.","family":"Ibraheem","sequence":"additional","affiliation":[{"name":"UNIVERSITY OF BAGHDAD, BAGHDAD, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kareem M.","family":"Lilo","sequence":"additional","affiliation":[{"name":"MINISTRY OF HEALTH, NATIONAL CENTER FOR DRUG RESEARCH AND CONTROL, BAGHDAD, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yaqoob A.","family":"Saleh","sequence":"additional","affiliation":[{"name":"MINISTRY OF HEALTH, NATIONAL BLOOD TRANSFUSION CENTER, BAGHDAD, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noor A.","family":"Kazim","sequence":"additional","affiliation":[{"name":"MINISTRY OF HEALTH, BLOOD TRANSFUSION SERVICES DEPARTMENT, BAGHDAD, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2022]]},"reference":[{"key":"ref0","doi-asserted-by":"crossref","unstructured":"1. 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Am J Gastroenterol. 2012; 107: 1460\u20136.","DOI":"10.1038\/ajg.2012.79"}],"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,6,27]],"date-time":"2022-06-27T15:37:31Z","timestamp":1656344251000},"score":1,"resource":{"primary":{"URL":"https:\/\/wiadlek.pl\/wp-content\/uploads\/archive\/2022\/05\/WLek202205209.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":20,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2022]]},"published-print":{"date-parts":[[2022,5]]}},"URL":"https:\/\/doi.org\/10.36740\/wlek202205209","archive":["Internet Archive"],"relation":{},"ISSN":["0043-5147"],"issn-type":[{"value":"0043-5147","type":"print"}],"subject":[],"published":{"date-parts":[[2022]]}}}