{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,12]],"date-time":"2026-09-12T08:04:08Z","timestamp":1789200248259,"version":"build-2803163510"},"reference-count":14,"publisher":"ALUNA","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiad Lek"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>The aim: To study the features of social dysfunction, assess the levels of social frustration and satisfaction with the quality of medical care in patients with schizophrenia on the background of somatic comorbidity. \nMaterials and methods: The study included 105 patients (55 women \u2013 52.38% and 50 men \u2013 47.61%) with a verified diagnosis of schizophrenia (F20.0-F20.3). The psychopathological condition of patients was assessed according to the \u201cPositive and Negative Syndrome Scale\u201d (PANSS). A special psychodiagnostic technique by L. I. Wasserman in the modification of V.V. Boiko was used to assess the level of social frustration. Peculiarities of social dysfunction were assessed based on the \u201cPersonal and Social Performance scale\u201d (PSP). \u201cThe Health Resource Use Questionnaire\u201d was used to obtain the information about the coverage of this patient with primary or specialized somatic care during the last three months. General and systematic examination of the patient was also performed, physical methods of diagnosis (palpation, percussion, auscultation) were applied, body mass index was calculated. Consultations of specialists, instrumental (ECG, ultrasound, Echo-CS, etc.) and laboratory diagnostic methods were prescribed depending on the detection or suspicion of concomitant somatic pathology. \nResults: The results showed significant social isolation of the respondents, their contacts were limited to communication with relatives and friends. This was confirmed by the data of social functioning on the PSP scale, according to which the most pronounced violations in the examined patients were found in the areas of \u201cpersonal and social relationships\u201d, \u201csocially useful activities, including work and study\u201d. It should be noted that the higher the rates of social dysfunction, the stronger the level of frustration (p&lt;0.05). In particular, the low level of satisfaction with the field of medical services due to its inaccessibility, according to respondents, attracts attention. According to the relatives, the main reason for this restriction was the patients\u2019 lack of awareness of their condition, neglect and indifference. \nConclusions: Further attention is required to develop strategies to improve comorbid treatment in the patients with schizophrenia regardless of whether this situation is the result of negative attitude of health professionals towards patients with mental illness, or the result of the patients\u2019 ignorance of their physical condition, or other factors.<\/jats:p>","DOI":"10.36740\/wlek202208110","type":"journal-article","created":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T07:08:53Z","timestamp":1662966533000},"page":"1876-1881","source":"Crossref","is-referenced-by-count":6,"title":["FEATURES OF SOCIAL DYSFUNCTION, ASSESSMENT OF LEVELS OF SOCIAL FRUSTRATION AND SATISFACTION WITH THE QUALITY OF MEDICAL CARE IN PATIENTS WITH SCHIZOPHRENIA ON THE BACKGROUND OF SOMATIC COMORBIDITY"],"prefix":"10.36740","volume":"75","author":[{"given":"Ivan R.","family":"Romash","sequence":"first","affiliation":[{"name":"IVANO-FRANKIVSK NATIONAL MEDICAL UNIVERSITY, IVANO-FRANKIVSK, UKRAINE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Iryna B.","family":"Romash","sequence":"additional","affiliation":[{"name":"IVANO-FRANKIVSK NATIONAL MEDICAL UNIVERSITY, IVANO-FRANKIVSK, UKRAINE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mykhaylo M.","family":"Pustovoyt","sequence":"additional","affiliation":[{"name":"IVANO-FRANKIVSK NATIONAL MEDICAL UNIVERSITY, IVANO-FRANKIVSK, UKRAINE"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22436","published-online":{"date-parts":[[2022]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. Moreno-K\u00fcstner B., Mart\u00edn C., Pastor L. Prevalence of psychotic disorders and its association with methodological issues. A systematic review and meta-analyses. PLOS ONE. 2018;13:e0195687. doi:10.1371\/journal. pone.0195687.","DOI":"10.1371\/journal.pone.0195687"},{"key":"ref1","doi-asserted-by":"publisher","unstructured":"2. Romash I. The role of metformin hydrochloride in complex therapy of disorders of carbohydrate metabolism in patients with paranoid schizophrenia treated with atypical antipsychotics. Mental Health: Global Challenges Journal. 2020;3:45-51. doi:10.32437\/mhgcj.v3i1.93.","DOI":"10.32437\/mhgcj.v3i1.93"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. Romash I.R., Vynnyk M.I. Dynamics of indicators of social functioning in case of metabolic syndrome in patients with paranoid schizophrenia on the background of atypical neuroleptic agent application and improvement of comorbidity. Art of Medicine. 2019; 4(12):102-9. doi:10.21802\/artm.2019.4.12.102.","DOI":"10.36927\/2079-0325-v27-is4-2019-11"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"4. Mateos-Aparicio P., Rodr\u00edguez-Moreno A. The impact of studying brain plasticity. Frontiers in cellular neuroscience . 2019; 13:66. doi:10.3389\/ fncel.2019.00066.","DOI":"10.3389\/fncel.2019.00066"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. Lee G., Zhou Y. NMDAR Hypofunction Animal Models of Schizophrenia. Front. Mol. Neurosci. 2019; 12:185. doi:10.3389\/fnmol.2019.00185.","DOI":"10.3389\/fnmol.2019.00185"},{"key":"ref5","doi-asserted-by":"publisher","unstructured":"6. Adel A. Brain NMDA Receptors in Schizophrenia and Depression. Biomolecules. 2020; 10: 947. doi:10.3390\/biom10060947.","DOI":"10.3390\/biom10060947"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"7. Leal G., Afonso P.M., Salazar I.L., Duarte C.B. Regulation of hippocampal synaptic plasticity by BDNF. Brain Research. 2015; 1621: 82-101. doi:10.1016\/j.brainres.2014.10.019.","DOI":"10.1016\/j.brainres.2014.10.019"},{"key":"ref7","doi-asserted-by":"publisher","unstructured":"8. Yamamori H., Hashimoto R., Ishima T. et al.. Plasma levels of mature brain-derived neurotrophic factor (BDNF) and matrix metalloproteinase-9 (MMP-9) in treatment-resistant schizophrenia treated with clozapine. Neuroscience Letters. 2013; 556: 37\u201341. doi:10.1016\/j.neulet.2013.09.059.","DOI":"10.1016\/j.neulet.2013.09.059"},{"key":"ref8","doi-asserted-by":"publisher","unstructured":"9. Janicijevic S.M., Dejanovic S.D., Borovcanin M. Interplay of Brain-Derived Neurotrophic Factor and Cytokines in Schizophrenia. Serbian Journal of Experimental and Clinical Research. 2018. doi:10.1515\/sjecr-2017-0031.","DOI":"10.1515\/sjecr-2017-0031"},{"key":"ref9","doi-asserted-by":"publisher","unstructured":"10. Manchia M., Primavera D., Deriu L. et al. The longitudinal trajectory of serum brain-derived neurotrophic factor (BDNF) levels in psychotic patients: a prospective observational study. European Neuropsychopharmacology. 2017; 27: 913.","DOI":"10.1016\/s0924-977x(17)31624-3"},{"key":"ref10","doi-asserted-by":"publisher","unstructured":"11. Popova N.K., Ilchibaeva T.V., Naumenko V.S. Neurotrophic factors (BDNF and GDNF) and the serotonergic system of the brain. Biochemistry. 2017; 82: 308\u201317. doi:10.1134\/s0006297917030099.","DOI":"10.1134\/s0006297917030099"},{"key":"ref11","doi-asserted-by":"publisher","unstructured":"12. Bitanihirwe B.K.Y., Woo T-U.W. A conceptualized model linking matrix metalloproteinase-9 to schizophrenia pathogenesis. Schizophrenia Research. 2020; 218: 28-35. doi:10.1016\/j.schres.2019.12.015.","DOI":"10.1016\/j.schres.2019.12.015"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"13. Hendriati D., Effendy E., Amin M.M. et al. Brain-Derived Neurotropic Factor Serum Level and Severity Symptom of Bataknese Male Patients with Schizophrenia in North Sumatera, Indonesia. Open Access Maced J Med Sci. 2019;7(12):1957-1961. doi:10.3889\/oamjms.2019.550.","DOI":"10.3889\/oamjms.2019.550"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"14. Vus V.V., Omelchenko L.M., Boiko O. et al. Public confidence in formal medicine: current context. Wiad Lek. 2021;74(11):2711-2716.","DOI":"10.36740\/wlek202111105"}],"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,5,15]],"date-time":"2023-05-15T09:45:49Z","timestamp":1684143949000},"score":1,"resource":{"primary":{"URL":"https:\/\/wiadlek.pl\/wp-content\/uploads\/archive\/2022\/08\/WLek202208110.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":14,"journal-issue":{"issue":"8","published-online":{"date-parts":[[2022]]},"published-print":{"date-parts":[[2022,8]]}},"URL":"https:\/\/doi.org\/10.36740\/wlek202208110","archive":["Internet Archive"],"relation":{},"ISSN":["0043-5147"],"issn-type":[{"value":"0043-5147","type":"print"}],"subject":[],"published":{"date-parts":[[2022]]}}}