{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,2]],"date-time":"2025-08-02T04:28:56Z","timestamp":1754108936896},"reference-count":24,"publisher":"ALUNA","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiad Lek"],"published-print":{"date-parts":[[2022,8]]},"abstract":"<jats:p>The aim: To determine the current prevalence of healthcare-associated tubo-ovarian infections in female and antimicrobial resistance of the responsible pathogens in Ukraine. \nMaterials and methods: We performed a retrospective multicenter cohort study was based on healthcare-associated infections surveillance data. Definitions of health\u00accare-associated tubo-ovarian infections were used from the CDC\/ NHSN. The susceptibility to antibiotics was determined by disk diffusion method according to the EUCAST. \nResults: Among all the 1,528 of women in this study, the prevalence of healthcare-associated tubo-ovarian infections was 31.2%. Of these cases, Salpingitis, Oophoritis, and tubo-ovarian abscess were 47.5%, 34% and 18.5%, respectively. Of all cases tubo-ovarian infections in female, 74.7% were detected after hospital discharge. The predominant pathogens were: Escherichia coli (27.7%), Enterobacter spp. (12.2%), Klebsiella pneumoniae (9.6%), Staphylococcus aureus (8.2%), Pseudomonas aeruginosa (8.1%), and Enterococcus faecalis (7.5%), followed by Proteus mirabilis (5.1%), Streptococcus spp. (4.5%), Staphylococcus epidermidis (4.4%), and Acinetibacter spp. (4%). Methicillin-resistance was ob\u00acserved in 16.8% of S. aureus (MRSA). No strains S.aureus and E. faecalis resistant to vancomycin. The overall proportion of extended spectrum beta-lactamases (ESBL) production among Enterobacteriaceae was 24.7%. The prevalence of ESBL production among E. coli isolates was 28.6% and among K. pneumoniae 12.8%. Resistance to third-generation cephalosporins was observed in 14.9% E.coli and 11.3% K. pneumoniae isolates. Carbapenem resistance was identified in 11.3% of P.aeruginosa isolates. \nConclusions: A healthcare-associated tubo-ovarian infections of the female in Ukraine is a common occurrence and many cases are caused by pathogens that are resistant to antibiotics.<\/jats:p>","DOI":"10.36740\/wlek202208211","type":"journal-article","created":{"date-parts":[[2022,9,21]],"date-time":"2022-09-21T11:32:25Z","timestamp":1663759945000},"page":"2003-2009","source":"Crossref","is-referenced-by-count":4,"title":["HEALTHCARE-ASSOCIATED TUBO-OVARIAN INFECTIONS IN UKRAINE: RESULTS OF A MULTICENTER STUDY (2020-2022)"],"prefix":"10.36740","volume":"75","author":[{"given":"Aidyn G.","family":"Salmanov","sequence":"first","affiliation":[{"name":"SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE, KYIV, UKRAINE; INSTITUTE OF PEDIATRICS, OBSTETRICS AND GYNECOLOGY OF THE NATIONAL ACADEMY OF MEDICAL SCIENCES OF UKRAINE, KYIV, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volodymyr A.","family":"Terekhov","sequence":"additional","affiliation":[{"name":"SUMY STATE UNIVERSITY, SUMY, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natalia S.","family":"Voloshynovych","sequence":"additional","affiliation":[{"name":"BUKOVINIAN STATE MEDICAL UNIVERSITY, CHERNIVTSI, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oksana B.","family":"Hrynchuk","sequence":"additional","affiliation":[{"name":"VOLYN REGIONAL MEDICAL CENTER OF ONCOLOGY, LUTSK, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oleg M.","family":"Ishchak","sequence":"additional","affiliation":[{"name":"TERNOPIL PERINATAL CENTER, TERNOPIL, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Victor O.","family":"Rud","sequence":"additional","affiliation":[{"name":"NATIONAL PIROGOV MEMORIAL MEDICAL UNIVERSITY, VINNYTSIA, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna V.","family":"Kolesnik","sequence":"additional","affiliation":[{"name":"LUTSK ACADEMY OF RECREATION TECHNOLOGIES AND LAW, LUTSK, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2022]]},"reference":[{"key":"ref0","unstructured":"1. 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