{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,6]],"date-time":"2026-07-06T02:18:30Z","timestamp":1783304310216,"version":"3.54.6"},"reference-count":15,"publisher":"ALUNA","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiad Lek"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>The aim: To identify clinical and hemodynamic factors, associated with left atrial spontaneous echo contrast (LASEC) (LASEC in general, and the dense LASEC), in non-valvular persistent atrial fibrillation (AF) patients with the duration of AF episode \u226590 days. \nMaterials and methods: The cross-sectional study consecutively enrolled 115 persistent AF patients with the duration of its episode \u226590 days (82 (71,3 %) males; mean age 59 \u00b1 11 years). Transthoracic (TEE) and transesophageal echocardiography (TEE) were performed. LASEC (by TEE) was observed in 79 (68,7 %) patients. The dense (moder\u00acate-to-severe) LASEC was detected in 23 (20,0 %) cases. \nResults: Heart failure (HF) stage C (OR 2,09 (95 % CI 1,24-3,53); p=0,006), lower TEE-derived left atrial appendage (LAA) flow velocity (FV) (OR 0,94 (95 % CI 0,91-0,98); p=0,003), and the presence of TTE-derived pulmonary hypertension (PH), appeared to be strongly associated with LASEC (AUC for logistic regression model: 0,83 [95 % \u0421I 0,75- 0,89]). The presence of diabetes mellitus type 2 (DM) (OR 2,34 (95 % CI 1,13-4,86); p=0,027), along with lower LAA FV (OR 0,83 (95 % CI 0,76-0,91); p&lt;0,001), were strongly associated with dense LASEC (AUC: 0,89 [95 % CI 0,82-0,94]). \nConclusions: The TEE-derived LASEC in patients with long term episodes (\u226590 days) of persistent AF was strongly associated with HF stage C and TTE-derived PH, and with lower TEE-derived LAA FV. The presence of DM, in addition to lower LAA FV, was related to dense LASEC.<\/jats:p>","DOI":"10.36740\/wlek202211118","type":"journal-article","created":{"date-parts":[[2022,12,31]],"date-time":"2022-12-31T22:34:51Z","timestamp":1672526091000},"page":"2652-2657","source":"Crossref","is-referenced-by-count":1,"title":["ASSOCIATION OF LEFT ATRIAL SPONTANEOUS ECHO CONTRAST WITH CLINICAL AND HEMODYNAMIC CHARACTERISTICS OF PATIENTS WITH LONG-TERM EPISODES OF PERSISTENT ATRIAL FIBRILLATION"],"prefix":"10.36740","volume":"75","author":[{"given":"Yaroslav V.","family":"Skybchyk","sequence":"first","affiliation":[{"name":"SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE STATE ADMINISTRATIVE DEPARTMENT, KYIV, UKRAINE; HEART INSTITUTE OF THE MINISTRY OF HEALTH OF UKRAINE, KYIV, UKRAINE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"\u041ayrylo \u041e.","family":"Mikhaliev","sequence":"additional","affiliation":[{"name":"STATE INSTITUTION OF SCIENCE \u00abRESEARCH AND PRACTICAL CENTER OF PREVENTIVE AND CLINICAL MEDICINE\u00bb, KYIV, UKRAINE"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oleg J.","family":"Zharinov","sequence":"additional","affiliation":[{"name":"SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE STATE ADMINISTRATIVE DEPARTMENT, KYIV, UKRAINE; HEART INSTITUTE OF THE MINISTRY OF HEALTH OF UKRAINE, KYIV, UKRAINE"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"22436","published-online":{"date-parts":[[2022]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. 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Echo Res Pract. 2019;6(2):R65-R73. doi:10.1530\/ERP-18-0083.","DOI":"10.1530\/erp-18-0083"}],"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,12,31]],"date-time":"2022-12-31T22:34:54Z","timestamp":1672526094000},"score":1,"resource":{"primary":{"URL":"https:\/\/wiadlek.pl\/wp-content\/uploads\/archive\/2022\/10\/WLek202211118.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":15,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2022]]},"published-print":{"date-parts":[[2022,11]]}},"URL":"https:\/\/doi.org\/10.36740\/wlek202211118","archive":["Internet Archive"],"relation":{},"ISSN":["0043-5147"],"issn-type":[{"value":"0043-5147","type":"print"}],"subject":[],"published":{"date-parts":[[2022]]}}}