{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,1,1]],"date-time":"2023-01-01T06:11:43Z","timestamp":1672553503430},"reference-count":17,"publisher":"ALUNA","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiad Lek"],"published-print":{"date-parts":[[2022,11]]},"abstract":"<jats:p>The aim: To identify clinical and angiographic factors, associated with fractional flow reserve (FFR), in stable coronary artery disease (CAD) patients. \nMaterials and methods: The study consecutively enrolled 68 patients with stable CAD (mean age (63\u00b18,0) ys) and angiographically intermediate coronary lesions (diameter stenosis 50-90 %), with FFR assessment. Stable angina of CCS classes II and III was diagnosed in 42 (62 %) and 15 (22 %) patients, respectively; left ventricular hypertrophy (LVH) \u2013 27 (40 %); severe coronary stenosis (SCS) (70-90 %) \u2013 46 (68 %). The overall CAD complexity was assessed by SYNTAX score. FFR \u00abnegative\u00bb group (FFRNEG) included the patients with non-significant FFRs (&gt;0,80) (n=28 [41 %]). In case of at least one significant FFR (\u22640,80), a patient was assigned to FFR \u00abpositive\u00bb group (FFRPOS) (n=40 [59 %]). \nResults: FFRPOS (vs. FFRNEG, respectively) was characterized by the higher frequency of angina class III (32 % vs. 7 %; p&lt;0,001), LVH (53 % vs. 21 %; p=0,010) and SCS (98 % vs. 25 %; p&lt;0,001). The SYNTAX score was strongly associated with FFR \u22640,70 and \u22640,65, and moderately \u2013 with FFR \u22640,65. \nConclusions: In patients with stable CAD and intermediate coronary artery stenosis, the presence of at least one functionally significant lesion (FFR \u22640,80) was associated with the higher prevalence of angina class III, LVH and more advanced coronary stenosis (\u226570 %). The greater overall CAD complexity increased the probability for the angiographically significant coronary lesions to be more functionally compromised.<\/jats:p>","DOI":"10.36740\/wlek202211120","type":"journal-article","created":{"date-parts":[[2022,12,31]],"date-time":"2022-12-31T22:34:45Z","timestamp":1672526085000},"page":"2665-2670","source":"Crossref","is-referenced-by-count":0,"title":["ASSOCIATION OF FRACTIONAL FLOW RESERVE WITH CLINICAL AND ANGIOGRAPHIC CHARACTERISTICS OF PATIENTS WITH STABLE CORONARY ARTERY DISEASE"],"prefix":"10.36740","volume":"75","author":[{"given":"Mykola V.","family":"Stan","sequence":"first","affiliation":[{"name":"SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE, KYIV, UKRAINE; HEART INSTITUTE OF THE MINISTRY OF HEALTH OF UKRAINE, KYIV, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u041ayrylo \u041e.","family":"Mikhaliev","sequence":"additional","affiliation":[{"name":"STATE INSTITUTION OF SCIENCE \u00abRESEARCH AND PRACTICAL CENTER OF PREVENTIVE AND CLINICAL MEDICINE\u00bb STATE ADMINISTRATIVE DEPARTMENT, KYIV, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Oleg J.","family":"Zharinov","sequence":"additional","affiliation":[{"name":"SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE, KYIV, UKRAINE; HEART INSTITUTE OF THE MINISTRY OF HEALTH OF UKRAINE, KYIV, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andriy V.","family":"Khokhlov","sequence":"additional","affiliation":[{"name":"HEART INSTITUTE OF THE MINISTRY OF HEALTH OF UKRAINE, KYIV, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anatolii M.","family":"Kravchenko","sequence":"additional","affiliation":[{"name":"STATE INSTITUTION OF SCIENCE \u00abRESEARCH AND PRACTICAL CENTER OF PREVENTIVE AND CLINICAL MEDICINE\u00bb STATE ADMINISTRATIVE DEPARTMENT, KYIV, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Borys M.","family":"Todurov","sequence":"additional","affiliation":[{"name":"SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE, KYIV, UKRAINE; HEART INSTITUTE OF THE MINISTRY OF HEALTH OF UKRAINE, KYIV, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2022]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. 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Angiology. 2019;70(5):423-430. doi:10.1177\/0003319718806394.","DOI":"10.1177\/0003319718806394"}],"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,12,31]],"date-time":"2022-12-31T22:34:53Z","timestamp":1672526093000},"score":1,"resource":{"primary":{"URL":"https:\/\/wiadlek.pl\/wp-content\/uploads\/archive\/2022\/10\/WLek202211120.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022]]},"references-count":17,"journal-issue":{"issue":"11","published-online":{"date-parts":[[2022]]},"published-print":{"date-parts":[[2022,11]]}},"URL":"https:\/\/doi.org\/10.36740\/wlek202211120","archive":["Internet Archive"],"relation":{},"ISSN":["0043-5147"],"issn-type":[{"value":"0043-5147","type":"print"}],"subject":[],"published":{"date-parts":[[2022]]}}}