{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,6,14]],"date-time":"2024-06-14T15:15:46Z","timestamp":1718378146067},"reference-count":37,"publisher":"ALUNA","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiad Lek"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:p>The aim: The aim of the study was to detect the antimicrobial susceptibility patterns and frequency of aminoglycosides resistance genes of Gram-negative bacteria isolated from pediatric patient with UTI. \nMaterials and methods: The study has been performed with a total of 500 urine specimens collected from pediatric patients under the age of 18 year suspected with UTI, admitted to hospitals in Al-Najaf province\/Iraq during the period from November 2018 to March 2019. \nResults: A total of 500 urine specimens had been tested, 120 (24%) had signi!cant bacteriuria, while there 380 (76%) had non-signi!cant bacteriuria. Escherichia coli represent about 70 (68.2%) followed by followed by 23 (22.5%) K. pneumoniae, 5 (4.9%) P. aeruginosa, 2 (1.9%) Proteus spp., 1 (0.9%) Enterobacter spp. and 1 (0.9%) Oligella uratolytic. The antimicrobial susceptibility pro!le of 102 Gram-negative isolates, revealed that 59 (58%) were multidrug resistant (MDR) and 38(37%) were extensive drug resistant (XDR). The PCR results of aminoglycosides resistance showing that 23 (74.1%) Gram-negative isolates had acc(6\u2019)-Ib gene and 12 (38.7%) Gram-negative isolates acc(3\u2019)-II gene. \nConclusions: A high frequency of multi-drug resistance and extensive-drug resistance of isolates were recognized, and an alarming percentage of amino-glycosides resistance to acc(6\u2019)-Ib and acc(3\u2019)-II.<\/jats:p>","DOI":"10.36740\/wlek202302108","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T11:52:49Z","timestamp":1680522769000},"page":"297-304","source":"Crossref","is-referenced-by-count":1,"title":["OCCURRENCE OF AMINOGLYCOSIDES RESISTANCE GENES ACC(6)-IB AND ACC(3)-II AMONG GRAM-NEGATIVE ISOLATES CAUSING URINARY TRACT INFECTION IN PEDIATRIC PATIENTS, NAJAF, IRAQ"],"prefix":"10.36740","volume":"76","author":[{"given":"Zainab Jaber","family":"Hadi","sequence":"first","affiliation":[{"name":"KUFA UNIVERSITY, KUFA, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ameer Sadiq","family":"Alkhayyat","sequence":"additional","affiliation":[{"name":"THE ISLAMIC UNIVERSITY, NAJAF, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alia Essa","family":"Bashbosh","sequence":"additional","affiliation":[{"name":"KUFA UNIVERSITY, KUFA, IRAQ"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2023]]},"reference":[{"key":"ref0","doi-asserted-by":"publisher","unstructured":"1. 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Drug Resist Updat.#2010; 13(6): 151-71.#doi: 10.1016\/j.drup.2010.08.003.","DOI":"10.1016\/j.drup.2010.08.003"}],"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T09:58:59Z","timestamp":1688119139000},"score":1,"resource":{"primary":{"URL":"https:\/\/wiadlek.pl\/wp-content\/uploads\/archive\/2023\/WLek2023021.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":37,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023]]},"published-print":{"date-parts":[[2023,2]]}},"URL":"https:\/\/doi.org\/10.36740\/wlek202302108","archive":["Internet Archive"],"relation":{},"ISSN":["0043-5147"],"issn-type":[{"value":"0043-5147","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]}}}