{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T10:12:29Z","timestamp":1688119949977},"reference-count":16,"publisher":"ALUNA","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Wiad Lek"],"published-print":{"date-parts":[[2023,2]]},"abstract":"<jats:p>The aim of the study is comparative assessment of the main risks of the global burden of cancer in the total burden of death. \nMaterials and methods: A comparative assessment of the main risks of the global burden of cancer within the overall burden of deaths was carried out based on the data of the Global Burden of Disease Study (GBD), data from the Center for Medical Statistics of the Ministry of Health of Ukraine, the National Cancer Registry of Ukraine. The methods of comparative analysis, systematic approach and system analysis, bibliosemantic and medical-statistical methods were used. \nResults: Higher attributable risk of death in most nosological forms of cancer among the population of Ukraine (bronchial, tracheal and lung cancer, laryn-geal, pharyngeal, lip and esophageal cancer) have been observed. Behavioral factors at the level of Ukraine, compared to the world level, are characterized by signi!cantly higher rates of attributable risk with regard to tobacco smoking (cancer of the larynx, pharynx, lower lip, esophagus) and alcohol consumption (pharynx, liver, lower lip). Environmental and occupational factors in Ukraine do not exceed the global exposure rates, and are lower for some cancer nosol-ogies, namely bronchial, tracheal, lung and laryngeal cancer. Unlike global trends, metabolic factors prevail among the mortality risks of patients with liver, esophageal, uterine and kidney cancer in Ukraine. \nConclusions: Behavioral, occupational, environmental and metabolic risk factors for cancer mortality have high attributable risk. Behavioral risk factors for cancer mortality have the most pronounced impact both globally and in Ukraine, and notably, for the majority of nosological forms of cancer in Ukraine mortality risks are higher compared to the global data.<\/jats:p>","DOI":"10.36740\/wlek202302115","type":"journal-article","created":{"date-parts":[[2023,4,3]],"date-time":"2023-04-03T11:52:31Z","timestamp":1680522751000},"page":"346-351","source":"Crossref","is-referenced-by-count":0,"title":["RISK FACTORS ASSOCIATED WITH CANCER PATHOLOGY"],"prefix":"10.36740","volume":"76","author":[{"given":"Arkadii H.","family":"Shulhai","sequence":"first","affiliation":[{"name":"I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nataliia O.","family":"Terenda","sequence":"additional","affiliation":[{"name":"I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Larysa Ya.","family":"Fedoniuk","sequence":"additional","affiliation":[{"name":"I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yurii M.","family":"Petrashyk","sequence":"additional","affiliation":[{"name":"I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nataliia Ya.","family":"Panchyshyn","sequence":"additional","affiliation":[{"name":"I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lesia M.","family":"Sas","sequence":"additional","affiliation":[{"name":"I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Viktoriia V.","family":"Piliponova","sequence":"additional","affiliation":[{"name":"NATIONAL PIROGOV MEMORIAL MEDICAL UNIVERSITY, VINNYTSIA, UKRAINE"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"22436","published-online":{"date-parts":[[2023]]},"reference":[{"key":"ref0","unstructured":"1. Rak v Ukrayini, 2020-2021. Zakhvoryuvanist', smertnist', pokaznyky diyal'nosti [Cancer in Ukraine, 2020-2021. Morbidity, mortality, performance indicators]. Bulletin of the National Chancery Register of Ukraine 2022; 23. Kyiv URL: http:\/\/www.ncru.inf.ua\/publications\/ BULL_23\/index.htm (UA)"},{"key":"ref1","unstructured":"2. Global Burden of Disease (GBD). URL: https:\/\/vizhub.healthdata.org\/gbd-compare\/"},{"key":"ref2","doi-asserted-by":"publisher","unstructured":"3. Kocarnik JM, Compton K, Dean FE et al. Cancer incidence, mortality, years of life lost, years lived with disability, and disability-adjusted life years for 29 cancer groups from 2010 to 2019: a systematic analysis for the Global Burden of Disease Study. 2019. JAMA Oncol.\"2022;\"8:\"420-444.","DOI":"10.3410\/f.733365235.793562611"},{"key":"ref3","doi-asserted-by":"publisher","unstructured":"4. Hecht SS Cigarette smoking and lung cancer: chemical mechanisms and approaches to prevention. Lancet Oncol.\"2002;\"3:\"461-469.","DOI":"10.1016\/s1470-2045(02)00815-x"},{"key":"ref4","doi-asserted-by":"publisher","unstructured":"5. Evans J, van Donkelaar A, Martin RV et al. Estimates of global mortality attributable to particulate air pollution using satellite imagery. 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(Phila). 2019;12(1);3\u201312.","DOI":"10.1158\/1940-6207.CAPR-18-0341"},{"key":"ref12","doi-asserted-by":"publisher","unstructured":"13. Chang JT, Anic GM, Rostron BL et al. Cigarette smoking reduction and health risks: a systematic review and meta-analysis.\"Nicotine and Tobacco Research. 2021;23(4);635-642.","DOI":"10.1093\/ntr\/ntaa156"},{"key":"ref13","doi-asserted-by":"publisher","unstructured":"14. Talluri R, Domgue JF, Gritz ER, Shete S Assessment of trends in cigarette smoking cessation after cancer diagnosis among US adults, 2000 to 2017.\"JAMA network open. 2020;3(8);e2012164-e2012164.","DOI":"10.1001\/jamanetworkopen.2020.12164"},{"key":"ref14","doi-asserted-by":"publisher","unstructured":"15. Viner B, Barberio AM, Haig TR, et al. The individual and combined e#ects of alcohol consumption and cigarette smoking on site-speci!c cancer risk in a prospective cohort of 26,607 adults: results from Alberta\u2019s Tomorrow Project.\"Cancer Causes & Control. 2019;30(12);1313-1326.","DOI":"10.1007\/s10552-019-01226-7"},{"key":"ref15","doi-asserted-by":"publisher","unstructured":"16. Avgerinos KI, Spyrou N, Mantzoros CS, Dalamaga M Obesity and cancer risk: Emerging biological mechanisms and perspectives.\"Metabolism. 2019;92;121-135.","DOI":"10.1016\/j.metabol.2018.11.001"}],"container-title":["Wiadomo\u015bci Lekarskie"],"original-title":[],"language":"en","deposited":{"date-parts":[[2023,6,30]],"date-time":"2023-06-30T09:58:31Z","timestamp":1688119111000},"score":1,"resource":{"primary":{"URL":"https:\/\/wiadlek.pl\/wp-content\/uploads\/archive\/2023\/WLek2023021.pdf"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023]]},"references-count":16,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2023]]},"published-print":{"date-parts":[[2023,2]]}},"URL":"https:\/\/doi.org\/10.36740\/wlek202302115","archive":["Internet Archive"],"relation":{},"ISSN":["0043-5147"],"issn-type":[{"value":"0043-5147","type":"print"}],"subject":[],"published":{"date-parts":[[2023]]}}}