{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T16:12:27Z","timestamp":1789661547353,"version":"4.0.1"},"reference-count":10,"publisher":"Walter de Gruyter GmbH","issue":"2","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2024,8,1]]},"abstract":"Abstract<\/jats:title>\n \n Introduction<\/jats:title>\n Undifferentiated embryonal sarcoma of the liver (UESL) is an aggressive tumor. There is no established treatment, and it is an uncommon tumor in adults. Treatment usually involves a combination of surgery, chemotherapy, and occasionally liver transplantation (LT). The role of LT in patients with irresectable UESL merits exploration.<\/jats:p>\n <\/jats:sec>\n \n Case Description<\/jats:title>\n A 20-year-old boy with a large palpable abdominal mass, shortness of breath, and weight loss presented to our clinic. His computed tomography scan showed showed a large cystic lesion measuring 11.5 \u00d7 22.7 \u00d7 23 cm, predominantly involving the left lobe and right anterior sector, with a biopsy consistent with UESL. The tumor was abutting to the right hepatic vein, with bland main portal vein thrombosis. Due to an irresectable tumor and deteriorating clinical condition, living donor LT was performed. The patient remains in good health at 16 months of follow-up.<\/jats:p>\n <\/jats:sec>\n \n Practical Implication<\/jats:title>\n In carefully selected patients with UESL, when other options are not feasible, LT might prolong survival and improve quality of life.<\/jats:p>\n <\/jats:sec>","DOI":"10.37029\/jcas.v10i2.599","type":"journal-article","created":{"date-parts":[[2024,8,16]],"date-time":"2024-08-16T19:41:30Z","timestamp":1723837290000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["Living Donor Liver Transplantation for Adult Hepatic Undifferentiated Embryonal Sarcoma: A Case Report"],"prefix":"10.2478","volume":"10","author":[{"given":"Usman","family":"Shafique","sequence":"first","affiliation":[{"name":"Department of Hepatobiliary Surgery and Liver Transplantation, Shifa International Hospital , Islamabad , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Azhar","family":"Shafi","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, Shifa International Hospital , Islamabad , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zafar","family":"Ali","sequence":"additional","affiliation":[{"name":"Department of Histopathology, Shifa International Hospital , Islamabad , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Belqees Yawar","family":"Faiz","sequence":"additional","affiliation":[{"name":"Department of Radiology, Shifa International Hospital , Islamabad , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abu Bakar Hafeez","family":"Bhatti","sequence":"additional","affiliation":[{"name":"Department of Hepatobiliary Surgery and Liver Transplantation, Shifa International Hospital , Islamabad , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2024,8,16]]},"reference":[{"key":"2026091715581456914_j_jcas.v10i2.599_ref_001","doi-asserted-by":"crossref","unstructured":"Babu BI, Bigam DL, Gilmour SM, Dajani KZ, Shapiro AM, Kneteman NM. Liver transplantation in locally unresectable, undifferentiated embryonal cell sarcoma. Transplant Direct 2021;7:e654.","DOI":"10.1097\/TXD.0000000000001106"},{"key":"2026091715581456914_j_jcas.v10i2.599_ref_002","doi-asserted-by":"crossref","unstructured":"Wu Z, Wei Y, Cai Z, Zhou Y. Long-term survival outcomes of undifferentiated embryonal sarcoma of the liver: A pooled analysis of 308 patients. ANZ J Surg 2020;90:1615-20.","DOI":"10.1111\/ans.15684"},{"key":"2026091715581456914_j_jcas.v10i2.599_ref_003","doi-asserted-by":"crossref","unstructured":"Pinamonti M, Vittone F, Ghiglione F, Borasi A, Silvestri S, Coverlizza S. Unexpected liver embryonal sarcoma in the adult: Diagnosis and treatment. Case Rep Surg 2018;2018:8362012.","DOI":"10.1155\/2018\/8362012"},{"key":"2026091715581456914_j_jcas.v10i2.599_ref_004","doi-asserted-by":"crossref","unstructured":"Shu B, Gong L, Huang X, Cao L, Yan Z, Yang S. Undifferentiated embryonal sarcoma of the liver in adults: Retrospective analysis of a case series and systematic review. Oncol Lett 2020;20:102.","DOI":"10.3892\/ol.2020.11963"},{"key":"2026091715581456914_j_jcas.v10i2.599_ref_005","doi-asserted-by":"crossref","unstructured":"Dhanasekaran R, Hemming A, Salazar E, Cabrera R. Rare case of adult undifferentiated (embryonal) sarcoma of the liver treated with liver transplantation: Excellent long-term survival. Case Reports Hepatol 2012;2012:519741.","DOI":"10.1155\/2012\/519741"},{"key":"2026091715581456914_j_jcas.v10i2.599_ref_006","doi-asserted-by":"crossref","unstructured":"Zhang C, Jia CJ, Xu C, Sheng QJ, Dou XG, Ding Y. Undifferentiated embryonal sarcoma of the liver: Clinical characteristics and outcomes. World J Clin Cases 2020;8:4763-72.","DOI":"10.12998\/wjcc.v8.i20.4763"},{"key":"2026091715581456914_j_jcas.v10i2.599_ref_007","doi-asserted-by":"crossref","unstructured":"Ziogas IA, Zamora IJ, Lovvorn Iii HN, Bailey CE, Alexopoulos SP. Undifferentiated embryonal sarcoma of the liver in children versus adults: A national cancer database analysis. Cancers (Basel) 2021;13:2918.","DOI":"10.3390\/cancers13122918"},{"key":"2026091715581456914_j_jcas.v10i2.599_ref_008","doi-asserted-by":"crossref","unstructured":"Plant AS, Busuttil RW, Rana A, Nelson SD, Auerbach M, Federman NC. A single-institution retrospective cases series of childhood undifferentiated embryonal liver sarcoma (UELS): Success of combined therapy and the use of orthotopic liver transplant. J Pediatr Hematol Oncol 2013;35:451-5.","DOI":"10.1097\/MPH.0b013e318271c948"},{"key":"2026091715581456914_j_jcas.v10i2.599_ref_009","doi-asserted-by":"crossref","unstructured":"Aronson DC, Meyers RL. Malignant tumors of the liver in children. Semin Pediatr Surg 2016;25:265-75.","DOI":"10.1053\/j.sempedsurg.2016.09.002"},{"key":"2026091715581456914_j_jcas.v10i2.599_ref_010","doi-asserted-by":"crossref","unstructured":"Bhatti AB, Naqvi W, Ali N, Khan NY, Zia HH, Faiz BY, et al. Textbook outcome among voluntary donors undergoing major living donor hepatectomy. Langenbecks Arch Surg 2022;407:2905-13.","DOI":"10.1007\/s00423-022-02578-6"}],"container-title":["Journal of Cancer and Allied Specialties"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sfu.ca\/jcas\/index.php\/jcas\/article\/download\/599\/519","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/reference-global.com\/pdf\/10.37029\/jcas.v10i2.599","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T15:58:23Z","timestamp":1789660703000},"score":1,"resource":{"primary":{"URL":"https:\/\/reference-global.com\/article\/10.37029\/jcas.v10i2.599"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8,1]]},"references-count":10,"journal-issue":{"issue":"2","published-online":{"date-parts":[[2024,8,16]]},"published-print":{"date-parts":[[2024,8,1]]}},"alternative-id":["10.37029\/jcas.v10i2.599"],"URL":"https:\/\/doi.org\/10.37029\/jcas.v10i2.599","relation":{},"ISSN":["2411-989X"],"issn-type":[{"value":"2411-989X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,8,1]]}}}