{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T15:04:07Z","timestamp":1789830247590,"version":"4.0.1"},"reference-count":9,"publisher":"Walter de Gruyter GmbH","issue":"1","license":[{"start":{"date-parts":[[2022,1,1]],"date-time":"2022-01-01T00:00:00Z","timestamp":1640995200000},"content-version":"unspecified","delay-in-days":0,"URL":"https:\/\/creativecommons.org\/licenses\/by-nc-sa\/4.0"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2022,1,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Primary lymphomas of the prostate are globally rare, representing &lt;0.1% of all prostatic neoplasms. Their rarity and non-specific symptomatology at presentation usually prompt a clinical diagnosis of benign prostatic hyperplasia or chronic prostatitis, leading to significant delay in diagnosis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Case Description<\/jats:title>\n                    <jats:p>A 32-year-old man presented to our clinic with complaints of difficult urination and perineal pain. An enlarged, hard and nodular prostate was palpable on digital rectal examination. Needle biopsy of the prostate was performed, which revealed diffuse large B-cell non-Hodgkin\u2019s lymphoma by immunohistochemical studies. Computed tomography (CT) scan showed a large pelvic mass arising from prostate encasing ureters with bilateral hydronephroureter. No abnormal finding was seen on abdominal CT scan and bone marrow biopsy. Therefore, the disease was classified into the clinical stage IAXE according to the Ann Arbor\u2019s criteria. The patient achieved complete response to six cycles of rituximab plus cyclophosphamide, doxorubicin, vincristine and prednisone chemotherapy with the central nervous system prophylaxis. He remained disease free, until 36 months after the end of chemotherapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Practical Implications<\/jats:title>\n                    <jats:p>According to the literature, the treatment and prognosis of primary lymphoma of the prostate are the same as that of other nodal lymphomas. The rituximab-based regimen should be considered in the management of prostatic diffuse large B-cell lymphoma.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.37029\/jcas.v8i1.439","type":"journal-article","created":{"date-parts":[[2022,1,12]],"date-time":"2022-01-12T05:12:24Z","timestamp":1641964344000},"page":"1-5","source":"Crossref","is-referenced-by-count":3,"title":["Primary Prostatic Diffuse Large B-Cell Lymphoma: A Case Report and Literature Review"],"prefix":"10.2478","volume":"8","author":[{"given":"Samia","family":"Yasmeen","sequence":"first","affiliation":[{"name":"Department of Medical Oncology , Prince Faisal Cancer Center , Buraidah , Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waqas","family":"Ahmad","sequence":"additional","affiliation":[{"name":"Department of Radiology , Chelsea and Westminster NHS Trust , London , United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omer","family":"Waqas","sequence":"additional","affiliation":[{"name":"Department of Pathology , Ittefaq Hospital (Trust) , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdul","family":"Hameed","sequence":"additional","affiliation":[{"name":"Department of Hematology\/Oncology , Ittefaq Hospital (Trust) , Lahore , Pakistan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"374","published-online":{"date-parts":[[2022,1,8]]},"reference":[{"key":"2026091914253088906_j_jcas.v8i1.439_ref_001","unstructured":"Lahyani M, Jabbour Y, Bakloul F, Karmouni T, Elkhader K, Koutani A, et al. Primary malignant lymphoma of the prostate: Report of a case achieving complete response chemotherapy. Elixir Urol 2015;86:35106-7."},{"key":"2026091914253088906_j_jcas.v8i1.439_ref_002","unstructured":"Petrakis G, Koletsa T, Karavasilis V, Rallis G, Bobos M, Karkavelas G, et al. Primary prostatic lymphoma with components of both diffuse large B-cell lymphoma (DLBCL) and MALT lymphoma. Hippokratia 2012;16):86."},{"key":"2026091914253088906_j_jcas.v8i1.439_ref_003","doi-asserted-by":"crossref","unstructured":"Warrick JI, Owens SR, Tomlins SA. Diffuse large B-cell lymphoma of the prostate. Arch Pathol Lab Med 2014;138:1286-9.","DOI":"10.5858\/arpa.2014-0276-CC"},{"key":"2026091914253088906_j_jcas.v8i1.439_ref_004","doi-asserted-by":"crossref","unstructured":"Hu S, Wang Y, Yang L, Yi L, Nian Y. Primary non-Hodgkin\u2019s lymphoma of the prostate with intractable hematuria: A case report and review of the literature. Oncol Lett 2015;9:1187-90.","DOI":"10.3892\/ol.2014.2829"},{"key":"2026091914253088906_j_jcas.v8i1.439_ref_005","doi-asserted-by":"crossref","unstructured":"Pan B, Han JK, Wang SC, Xu A. Positron emission tomography\/computerized tomography in the evaluation of primary non-Hodgkin\u2019s lymphoma of prostate. World J Gastroenterol 2013;19: 6699-702.","DOI":"10.3748\/wjg.v19.i39.6699"},{"key":"2026091914253088906_j_jcas.v8i1.439_ref_006","doi-asserted-by":"crossref","unstructured":"Taleb A, Ismaili N, Belbaraka R, Bensouda A, Elghissassi I, Elmesbahi O, et al. Primary lymphoma of the prostate treated with rituximab-based chemotherapy: A case report and review of the literature. Cases J 2009;2:8875.","DOI":"10.4076\/1757-1626-2-8875"},{"key":"2026091914253088906_j_jcas.v8i1.439_ref_007","doi-asserted-by":"crossref","unstructured":"Kakkar A, Rajeshwari M, Bhethanabhotla S, Kaur K, Jain D, Gogia A, et al. Primary diffuse large B-cell lymphoma of the prostate: A report of two cases with diagnostic considerations. J Cancer Res Ther 2015;11:977-9.","DOI":"10.4103\/0973-1482.176122"},{"key":"2026091914253088906_j_jcas.v8i1.439_ref_008","doi-asserted-by":"crossref","unstructured":"Bostwick DG, Iczkowski KA, Amin MB, Discigil G, Osborne B. Malignant lymphoma involving the prostate. Cancer 1998;83:732-8.","DOI":"10.1002\/(SICI)1097-0142(19980815)83:4<732::AID-CNCR15>3.0.CO;2-T"},{"key":"2026091914253088906_j_jcas.v8i1.439_ref_009","doi-asserted-by":"crossref","unstructured":"Antunes AA, Dall\u2019Oglio M, Srougi M. Primary lymphoma of the prostate: A rare cause of urinary obstruction. Int Braz J Urol 2004;30:410-2.","DOI":"10.1590\/S1677-55382004000500011"}],"container-title":["Journal of Cancer and Allied Specialties"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sfu.ca\/jcas\/index.php\/jcas\/article\/download\/439\/453","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/reference-global.com\/pdf\/10.37029\/jcas.v8i1.439","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,9,19]],"date-time":"2026-09-19T14:25:40Z","timestamp":1789827940000},"score":1,"resource":{"primary":{"URL":"https:\/\/reference-global.com\/article\/10.37029\/jcas.v8i1.439"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,1]]},"references-count":9,"journal-issue":{"issue":"1","published-online":{"date-parts":[[2022,1,8]]},"published-print":{"date-parts":[[2022,1,1]]}},"alternative-id":["10.37029\/jcas.v8i1.439"],"URL":"https:\/\/doi.org\/10.37029\/jcas.v8i1.439","relation":{},"ISSN":["2411-989X"],"issn-type":[{"value":"2411-989X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,1]]}}}