{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T11:32:37Z","timestamp":1747222357863,"version":"3.40.5"},"reference-count":0,"publisher":"Sociedad Espanola de Quimioterapia","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Esp Quimioter"],"published-print":{"date-parts":[[2024,7,1]]},"abstract":"<jats:p>Skin and soft tissue infections (SSTIs), and particularly diabetic-related foot infections (DFI), present diagnostic and therapeutic complexities, often leading to severe complications. This study aims to evaluate the in vitro efficacy of cefditoren and amoxicillin\/clavulanic acid against typical DFI pathogens. Clinical samples from 40 patients with mild SSTIs were analyzed, revealing a predominance of Staphylococcus spp. and Streptococcus spp. species. Cefditoren exhibited activity against 90% of isolates, with superior potency over amoxicillin\/clavulanic acid. These findings underscore the utility of cefditoren in empirical treatment of DFI, although a larger sample size would be desirable for further validation.<\/jats:p>","DOI":"10.37201\/req\/028.2024","type":"journal-article","created":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T15:23:24Z","timestamp":1719933804000},"page":"356-359","source":"Crossref","is-referenced-by-count":0,"title":["Exploring therapeutic options for mild diabetic-related foot infections: a comparative in vitro study of cefditoren versus amoxicillin\/clavulanic acid"],"prefix":"10.37201","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-0859-008X","authenticated-orcid":false,"given":"Luis","family":"Alou","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8037-4007","authenticated-orcid":false,"given":"Elena","family":"G\u00f3mez-Rubio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0830-4095","authenticated-orcid":false,"given":"Mar\u00eda-Jos\u00e9","family":"Gim\u00e9nez Mestre","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4674-3822","authenticated-orcid":false,"given":"Francisco-Javier","family":"Alvaro-Afonso","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8375-055X","authenticated-orcid":false,"given":"Pilar","family":"Coronel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0212-2194","authenticated-orcid":false,"given":"David","family":"Sevillano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"23328","published-online":{"date-parts":[[2024,6,13]]},"container-title":["Revista Espa\u00f1ola de Quimioterapia"],"original-title":[],"deposited":{"date-parts":[[2024,7,2]],"date-time":"2024-07-02T15:56:46Z","timestamp":1719935806000},"score":1,"resource":{"primary":{"URL":"https:\/\/seq.es\/abstract\/rev-esp-quimioter-2024-june-13-2\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,13]]},"references-count":0,"journal-issue":{"issue":"4","published-online":{"date-parts":[[2024,7,1]]},"published-print":{"date-parts":[[2024,7,1]]}},"URL":"https:\/\/doi.org\/10.37201\/req\/028.2024","relation":{},"ISSN":["0214-3429","1988-9518"],"issn-type":[{"type":"print","value":"0214-3429"},{"type":"electronic","value":"1988-9518"}],"subject":[],"published":{"date-parts":[[2024,6,13]]}}}