{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,14]],"date-time":"2025-05-14T11:32:38Z","timestamp":1747222358116,"version":"3.40.5"},"reference-count":0,"publisher":"Sociedad Espanola de Quimioterapia","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Esp Quimioter"],"published-print":{"date-parts":[[2024,9,11]]},"abstract":"<jats:p>Introduction. Our aim was to analyse the relation between serial values of the indocyanine green plasma disappearance rate (ICG-PDR) with hospital mortality in the first 48 hours of ICU admission in patients with septic shock. Methods. A prospective observational study was carried out over 12 months of patients admitted to the ICU with septic shock. Each patient underwent noninvasive determination of ICG-PDR at 24 and 48 hours with the LiMON\u00ae module. Follow-up was performed until hospital discharge or exitus. Results. 63 patients. Age 61.1\u00b112.3 years. 60.3% men. SOFA score on admission 8.7\u00b13.3, APACHE II score was 27.9\u00b110.7 points. A total of 44.4% of patients died. The ICG-PDR values in the first 24 hours of ICU admission were lower in nonsurvivors: 10.5 (5.7-13.0)%\/min vs. 15.9 (11.4-28.0)%\/min, p &lt;0.001. Furthermore, in nonsurvivors, there was no improvement in ICG-PDR between 24 h and 48 h, while in survivors, there was an increase of 25%: 15.9 (11.4-28.0)%\/min and 20.9 (18.0-27.0)%\/min, p=0.020. The silhouette measure of ICG-PDR cohesion and separation for the clusters analysed (nonsurvivors and survivors) was satisfactory (0.6). ICG-PDR&lt;11.7%\/min was related to in-hospital mortality, ICG-PDR&gt; 18%\/min to survival, and the interval between 11.7% and 18%\/min covered a range of uncertainty. In the two-stage cluster, ICG-PDR, SOFA and APACHE II present satisfactory predictive scores 24 hours after patient admission. Conclusions. ICG-PDR in our setting is a useful clinical prognostic tool and could optimise the decision tree in patients with septic shock.<\/jats:p>","DOI":"10.37201\/req\/029.2024","type":"journal-article","created":{"date-parts":[[2024,6,27]],"date-time":"2024-06-27T11:50:08Z","timestamp":1719489008000},"page":"401-408","source":"Crossref","is-referenced-by-count":0,"title":["Use of noninvasive measurement of the indocyanine green plasma disappearance rate in patients with septic shock"],"prefix":"10.37201","volume":"37","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8256-1781","authenticated-orcid":false,"given":"Isabel","family":"Guti\u00e9rrez-Morales","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8612-5557","authenticated-orcid":false,"given":"Ana","family":"Loza-V\u00e1zquez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Antonio","family":"S\u00e1nchez-Rom\u00e1n","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3702-2540","authenticated-orcid":false,"given":"Antonio","family":"Grilo-Reina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1045-3607","authenticated-orcid":false,"given":"Mar\u00eda Asunci\u00f3n","family":"Navarro-Puerto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"23328","published-online":{"date-parts":[[2024,6,28]]},"container-title":["Revista Espa\u00f1ola de Quimioterapia"],"original-title":[],"deposited":{"date-parts":[[2024,9,11]],"date-time":"2024-09-11T10:57:29Z","timestamp":1726052249000},"score":1,"resource":{"primary":{"URL":"https:\/\/seq.es\/abstract\/rev-esp-quimioter-2024-june-28-2\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,6,28]]},"references-count":0,"journal-issue":{"issue":"5","published-online":{"date-parts":[[2024,9,11]]},"published-print":{"date-parts":[[2024,9,11]]}},"URL":"https:\/\/doi.org\/10.37201\/req\/029.2024","relation":{},"ISSN":["0214-3429","1988-9518"],"issn-type":[{"type":"print","value":"0214-3429"},{"type":"electronic","value":"1988-9518"}],"subject":[],"published":{"date-parts":[[2024,6,28]]}}}