{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T08:57:53Z","timestamp":1779008273517,"version":"3.51.4"},"reference-count":0,"publisher":"Sociedad Espanola de Quimioterapia","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Esp Quimioter"],"published-print":{"date-parts":[[2021,2,1]]},"abstract":"<jats:p>Objectives. We assessed the prevalence of potentially inappropriate prescriptions (PIP) among older (\u2265 65 years) people living with HIV (PLWHIV). Additionally, the secondary objective was to analyse the relationship between pharmacotherapeutic complexity and compliance with STOPP-Beers criteria associated with Top-10 drugs classes to avoid (TOP-10-A) of European AIDS Clinical Society (EACS) guidelines. Methods. This was a cross-sectional observational single-centre study. PLWHIV aged 65 years-old or over on ART attending at hospital pharmacy outpatient service from December-2019 to March-2020 were included. Patients were classified by age group: 65-69, 70-75 and more than 75 years. Moreover, was analysed the relationship between pharmacotherapeutic complexity and compliance with STOPP-Beers Criteria associated with Top-10-A drugs. Results. A total of 19 individuals were included. Overall polypharmacy was observed in 16 PLWHIV (84.2%). A PIP included Top-10-A was identified in 9 (47.4%) PLWHIV. Benzodiazepines were the most prevalent group of prescribed drugs in 6 patients (30.0%). Complex patients were observed in 57.9% (MRCI index value greater than 11.25). Similarly, the sum of criteria STOPP-Beers was higher in older patients. Student\u2019s t test showed the existence of a statistically significant relationship between pharmacotherapeutic complexity and sum of STOPP-Beers Criteria (p &lt;0.05) in elderly PLWHIV. Conclusions. Prescription of PIPs is highly prevalent in older PLWHIV. Consistent with data, presence of PIPs were associated a presence of higher pharmacotherapeutic complexity and sum of STOPP-Beers Criteria. The basis for a new revised care plan for PLWHIV focussed on optimising overall patient care pharmacotherapeutic complexity and its possible consequences.<\/jats:p>","DOI":"10.37201\/req\/087.2020","type":"journal-article","created":{"date-parts":[[2020,12,30]],"date-time":"2020-12-30T03:31:33Z","timestamp":1609299093000},"page":"28-32","source":"Crossref","is-referenced-by-count":4,"title":["Prevalence of prescription of the Top-10 drug classes to avoid in elderly people living with HIV in a real practice cohort"],"prefix":"10.37201","volume":"34","author":[{"given":"Enrique","family":"Contreras Mac\u00edas","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reyes","family":"Serrano Gim\u00e9nez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ram\u00f3n","family":"Morillo Verdugo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"name":"Servicio de Farmacia Hospitalaria, Hospital Universitario Virgen de Valme. Sevilla. Spain","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"23328","published-online":{"date-parts":[[2020,12,30]]},"container-title":["Revista Espa\u00f1ola de Quimioterapia"],"original-title":[],"deposited":{"date-parts":[[2021,2,9]],"date-time":"2021-02-09T01:20:41Z","timestamp":1612833641000},"score":1,"resource":{"primary":{"URL":"https:\/\/seq.es\/abstract\/rev-esp-quimioter-2020-december-30-2\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,30]]},"references-count":0,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,2,1]]}},"URL":"https:\/\/doi.org\/10.37201\/req\/087.2020","relation":{},"ISSN":["0214-3429","1988-9518"],"issn-type":[{"value":"0214-3429","type":"print"},{"value":"1988-9518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,12,30]]}}}