{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,9]],"date-time":"2026-07-09T14:31:21Z","timestamp":1783607481349,"version":"3.55.0"},"reference-count":0,"publisher":"Sociedad Espanola de Quimioterapia","issue":"Suppl1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Esp Quimioter"],"abstract":"<jats:p>Aspergillus spp. is the fungus most frequently producing ventilator-associated pneumonia (VAP), constituting 8% of them. This risk is significantly increased in onco-hematological patients: solid organ transplant recipients, chronic obstructive pulmonary disease (COPD), corticotherapy, cirrhosis, solid cancer, or viral pneumonias. The European Organization for Research and Treatment of Cancer Mycoses (EORT\/MSG criteria) developed for onco-hematological patients with angioinvasive forms of aspergillosis have important limitations for broncho-pulmonary forms, such as aspergillosis cases in the ICU. In recent years, new diagnostic criteria were developed to have a greater role in broncho-alveolar lavage, especially GM and lateral flow assay (LFA). Voriconazole and isavuconazole are the first treatment option. However, drug-drug interaction, level requirements, toxicity, and QT-interval modification are limitations that may favor isavuconazole or liposomal amphotercin B in the ICU.<\/jats:p>","DOI":"10.37201\/req\/s01.21.2022","type":"journal-article","created":{"date-parts":[[2022,4,30]],"date-time":"2022-04-30T07:26:27Z","timestamp":1651303587000},"page":"97-103","source":"Crossref","is-referenced-by-count":8,"title":["Diagnostic and therapeutic approach to fungal pneumonia in the critically ill patient"],"prefix":"10.37201","volume":"35","author":[{"given":"Jes\u00fas","family":"Fort\u00fan","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"23328","published-online":{"date-parts":[[2022,4,22]]},"container-title":["Revista Espa\u00f1ola de Quimioterapia"],"original-title":[],"deposited":{"date-parts":[[2022,5,4]],"date-time":"2022-05-04T07:47:14Z","timestamp":1651650434000},"score":1,"resource":{"primary":{"URL":"https:\/\/seq.es\/abstract\/rev-esp-quimioter-2022-april-21\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,4,22]]},"references-count":0,"journal-issue":{"issue":"Suppl1","published-online":{"date-parts":[[2022,4,22]]},"published-print":{"date-parts":[[2022,4,22]]}},"URL":"https:\/\/doi.org\/10.37201\/req\/s01.21.2022","relation":{},"ISSN":["0214-3429","1988-9518"],"issn-type":[{"value":"0214-3429","type":"print"},{"value":"1988-9518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,4,22]]}}}