{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T04:04:43Z","timestamp":1789531483360,"version":"build-2803163510"},"reference-count":0,"publisher":"Sociedad Espanola de Quimioterapia","issue":"Suppl3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Rev Esp Quimioter"],"published-print":{"date-parts":[[2022,10,24]]},"abstract":"<jats:p>In response to SARS-CoV-2 infection, the immune system physiologically upregulates to try to clear the virus from the body; failure to compensate for this inflammatory response with an anti-inflammatory response leads to dysregulation of the immune system that ultimately leads to a situation of uncontrolled hyperinflammation called cytokine storm. This cytokine storm can cause ARDS or multi-organ failure leading to patient death. This review exposes the different mechanisms of the inflammatory response in COVID-19 infection and the therapeutic options to treat this process.<\/jats:p>","DOI":"10.37201\/req\/s03.02.2022","type":"journal-article","created":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T16:10:02Z","timestamp":1666627802000},"page":"6-9","source":"Crossref","is-referenced-by-count":5,"title":["Management of hyperinflammation in COVID-19 patients"],"prefix":"10.37201","volume":"35","author":[{"given":"Borja","family":"Suberviola","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Cuenca Fito","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"23328","published-online":{"date-parts":[[2022,10,24]]},"container-title":["Revista Espa\u00f1ola de Quimioterapia"],"original-title":[],"deposited":{"date-parts":[[2022,10,24]],"date-time":"2022-10-24T16:10:36Z","timestamp":1666627836000},"score":1,"resource":{"primary":{"URL":"https:\/\/seq.es\/abstract\/rev-esp-quimioter-2022-suppl3-02\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,10,24]]},"references-count":0,"journal-issue":{"issue":"Suppl3","published-online":{"date-parts":[[2022,10,24]]},"published-print":{"date-parts":[[2022,10,24]]}},"URL":"https:\/\/doi.org\/10.37201\/req\/s03.02.2022","relation":{},"ISSN":["0214-3429","1988-9518"],"issn-type":[{"value":"0214-3429","type":"print"},{"value":"1988-9518","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,10,24]]}}}