{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:25:03Z","timestamp":1777371903561,"version":"3.51.4"},"reference-count":7,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[2003,8,1]],"date-time":"2003-08-01T00:00:00Z","timestamp":1059696000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acupuncture &amp; Electro-Therapeutics Research: International Journal of Integrated Medicine"],"published-print":{"date-parts":[[2003,8]]},"abstract":"<jats:p>\n                    The Bi-Digital O-Ring Test has been very useful in the identification of bacterial and viral infections, as well as other etiological agents, in difficult clinical cases. Case report of a patient with multiple hepatic abscesses (pylephlebitis induced hepatic abscess is the most difficult abscess to treat), in which the etiological agent was suggested through Bi-Digital O-Ring Test with excellent clinical evolution after modification of previously ineffective multi anti-microbial treatment is presented. 45 years old, female with a history of pain at right hypochondria for 15 days, with jaundice, oscillating fever and shivering. Computerized tomography showed liver with multiples nodules in the parenchyma with additional appendicitis. An appendectomy was performed with drainage of intra abdominal abscesses Treatment with metronidazol, ceftazidim and amicacine was performed with no improvement while the general condition of the patient was deteriorating progressively in the following 3 weeks. Bi-Digital O-Ring Test was then performed to determine the etiological agent and the drug compatibility test among effective antimicrobial agents. Based on the Bi-Digital O-Ring Test, the main etiological agent was found to be\n                    <jats:italic toggle=\"yes\">Enterobacter<\/jats:italic>\n                    aerogenes. Amongst the three antibiotics that were being used, only metronidazol was effective and the other 2 was cancelled its effect. Based on Bi-Digital O-Ring Test findings two new antibiotics (cefadroxil and imipenen), were added to metronidazol and additional cilantro tablets by Hayashibara, Japan was given, and Selective Drug Uptake Enhancement Method performed, with excellent clinical, laboratory testing and tomography improvement within 10 days. Bi-Digital O-Ring Test suggested the etiological agent, and effective and mutually compatible antibiotics for treating the abscesses which resulted in a good clinical evolution, characterized by relief of fever and reduction of the hepatic abscesses in a short period and followed complete disappearance of hepatic abscess.\n                  <\/jats:p>","DOI":"10.3727\/036012903815901570","type":"journal-article","created":{"date-parts":[[2015,8,28]],"date-time":"2015-08-28T22:04:55Z","timestamp":1440799495000},"page":"201-206","source":"Crossref","is-referenced-by-count":1,"title":["The Importance of Bi-Digital O-Ring Test in the Treatment of Multiple Hepatic Abscesses: A Case History"],"prefix":"10.1177","volume":"28","author":[{"given":"S.","family":"Iwasa","sequence":"first","affiliation":[{"name":"Orthopedic Surgeon, Director of Brazilian Medical Acupuncture Association"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. B.","family":"Neves","sequence":"additional","affiliation":[{"name":"Gastroenterologist, Medical Assistant of the Department of Internal Medicine, Medical School, Federal University of Sao Paulo-UNIFESP"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A. C.","family":"Lopes","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Medical School, Federal University of S\u00e3o Paulo-UNIFESP"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[2003,8]]},"reference":[{"key":"e_1_3_1_2_2","article-title":"-\u00a0A Pr\u00e1tica do Teste do Anel Bi-DigitaL\u00a01 ed.; Editora AMBA","author":"Omura Y.","year":"2000","unstructured":"OmuraY. -\u00a0A Pr\u00e1tica do Teste do Anel Bi-DigitaL\u00a01 ed.; Editora AMBA, S\u00e3o Paulo (Translated from Japanese Book to Portuguese by Takashi Jojima and Sumie Iwasa), 2000","journal-title":"S\u00e3o Paulo (Translated from Japanese Book to Portuguese by Takashi Jojima and Sumie Iwasa)"},{"key":"e_1_3_1_3_2","article-title":"-\u00a0Practice of Bi-Digital O-Ring Test.\u00a0Ido-No-Nippon-Sha","author":"Omura Y.","year":"1992","unstructured":"OmuraY. -\u00a0Practice of Bi-Digital O-Ring Test.\u00a0Ido-No-Nippon-Sha, Tokyo, 4th\u00a0Ed, 1992","journal-title":"Tokyo, 4th\u00a0Ed"},{"key":"e_1_3_1_4_2","doi-asserted-by":"crossref","unstructured":"OmuraY. - Role of Mercury in Resistant Infections &\u00a0Effective Treatment of Chlamydia Trachomatis and Herpes Family Viral Infections (and Potential Treatment of Cancer) and Delivering Effective Antibiotics Using Various Drug Uptake Enhancement Methods.\u00a0Acupuncture &\u00a0Electro-Therapeutics Research. Int. J.\u00a0 Vol.20. Pp 195\u2013229 1995.","DOI":"10.3727\/036012995816357014"},{"key":"e_1_3_1_5_2","doi-asserted-by":"crossref","unstructured":"OmuraY. - Transmission of Molecular Information through Electro-Magnetic Waves with Different Frequencies and its Applicatios Non-Invasive Diagnosis of Patients as well as Detection from Patient\u2019s X-ray Film of Visible and Not Visible Medical Information: Part I.\u00a0Acupuncture &\u00a0Electro-Therapeutics Research. Int. J.\u00a0 Vol. 19 pp 3963 1994.","DOI":"10.3727\/036012994816357394"},{"key":"e_1_3_1_6_2","doi-asserted-by":"publisher","DOI":"10.3727\/036012994816357286"},{"key":"e_1_3_1_7_2","first-page":"355","article-title":"Diehl, AM - Bacterial infections of the Liver and Biliary System In Surawicz, C &\u00a0Owen, RL,\u00a0Gastrointestinal and Hepatic Infections, led; Philadelphia, W.B","author":"Canto MIF","year":"1995","unstructured":"CantoMIF& Diehl, AM - Bacterial infections of the Liver and Biliary System In Surawicz, C &\u00a0Owen, RL,\u00a0Gastrointestinal and Hepatic Infections, led; Philadelphia, W.B. Saunders Company, 1995. p 355\u2013389","journal-title":"Saunders Company"},{"key":"e_1_3_1_8_2","first-page":"g249","article-title":"Manual de Diagn\u00f3stico das Doencas Hep\u00e1ticas\u00a0- no paciente adulto e pedi\u00e1trico","author":"Fonseca JC.","unstructured":"FonsecaJC., Manual de Diagn\u00f3stico das Doencas Hep\u00e1ticas\u00a0- no paciente adulto e pedi\u00e1trico. Editores Parise, E.R.& Porta G. p\u00e1 g249\u201356, Sao Paulol999.","journal-title":"Editores Parise, E.R.& Porta G. p\u00e1"}],"container-title":["Acupuncture &amp; Electro-Therapeutics Research: International Journal of Integrated Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3727\/036012903815901570","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3727\/036012903815901570","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3727\/036012903815901570","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T08:51:55Z","timestamp":1777366315000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3727\/036012903815901570"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,8]]},"references-count":7,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2003,8]]}},"alternative-id":["10.3727\/036012903815901570"],"URL":"https:\/\/doi.org\/10.3727\/036012903815901570","relation":{},"ISSN":["0360-1293","2167-9010"],"issn-type":[{"value":"0360-1293","type":"print"},{"value":"2167-9010","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,8]]}}}