{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T03:51:37Z","timestamp":1782532297096,"version":"3.54.5"},"reference-count":70,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2011,2,1]],"date-time":"2011-02-01T00:00:00Z","timestamp":1296518400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Acupuncture &amp; Electro-Therapeutics Research: International Journal of Integrated Medicine"],"published-print":{"date-parts":[[2011,2]]},"abstract":"<jats:p>\n                    There are many causes of frequent urination. Whenever water or fluids are consumed, the patient has to urinate within 10 or 20 min. Often urinary bladder examinations &amp; blood tests show no significant abnormalities, &amp; treatment by anti-bacterial or anti-viral agents does not improve the symptoms significantly. In intractable frequent urination with difficulty holding urine, as well as other intractable medical problems such as frequent coughing, white pus in gingiva, infection of the apex of a root canalled tooth, slow-healing wounds, &amp; ALS, the authors often found coexisting mixed infections of\n                    <jats:italic toggle=\"yes\">Candida albicans<\/jats:italic>\n                    (C.A.),\n                    <jats:italic toggle=\"yes\">Helicobacter pylori<\/jats:italic>\n                    (H.P.), &amp;\n                    <jats:italic toggle=\"yes\">Cytomegalovirus<\/jats:italic>\n                    (CMV) with or without additional bacterial (Chlamydia trachomatis, etc.) or viral infections &amp; increased Asbestos, with or without Hg deposits. We often found various degrees of mixed infections with C.A., H.P., &amp; CMV in the external sphincters of the urethra &amp; in the Trigone of the urinary bladder which consists of 1) a horizontal, band-like area between the 2 ureter openings &amp; 2) the funnel shaped part of the Trigone at the lower half of the urinary bladder. In the coexistence of significant amounts of C.A., H.P. &amp; CMV, the infection cannot be reduced by otherwise effective medicines for H.P. &amp; CMV. However, one optimal dose of Diflucan, or Caprylic acid taken orally or externally applied, rapidly reduced the symptoms significantly. We found the best treatment is to give a combination of an optimal dose of Caprylic acid orally in the form of \u201cCaprilyCare\u201d or \u201cCaprylic Acid,\u201d with a capsule of Omega-3 Fish Oil as an anti-viral agent, Amoxicillin, Substance Z &amp; a Cilantro tablet. We found that an optimal dose of Caprylic acid increases normal cell telomere (NCT) to a desirable 750 ng BDORT units while Diflucan increases NCT by only 25 ng BDORT units, &amp; with Omega-3 fish oil, leads to a mutual cancellation of both drugs. Thus, Caprylic acid is superior to &amp; less expensive than Diflucan, &amp; has potential application for anti-cancer, anti-aging, anti-Alzheimer's disease, anti- Autism, anti-infection, &amp; general circulatory improvement.\n                  <\/jats:p>","DOI":"10.3727\/036012911803860886","type":"journal-article","created":{"date-parts":[[2014,1,24]],"date-time":"2014-01-24T19:31:11Z","timestamp":1390591871000},"page":"19-64","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Caprylic Acid in the Effective Treatment of Intractable Medical Problems of Frequent Urination, Incontinence, Chronic Upper Respiratory Infection, Root Canalled Tooth Infection, ALS, etc., Caused by Asbestos &amp; Mixed Infections of\n                    <i>Candida albicans, Helicobacter pylori &amp; Cytomegalovirus<\/i>\n                    With or Without Other Microorganisms &amp; Mercury"],"prefix":"10.1177","volume":"36","author":[{"given":"Yoshiaki","family":"Omura","sequence":"first","affiliation":[{"name":"Director of Medical Research, Heart Disease Research Foundation"},{"name":"Adjunct Prof. Dept. of Family &amp; Community Medicine, New York Medical College"},{"name":"President &amp; Prof., International College of Acupuncture &amp; Electro-Therapeutics"},{"name":"Former Visiting Research Prof., Dept. of Electrical Engineering, Manhattan College"},{"name":"Former \u201cMaitre de Recherche of INSERM\u201d, National Institute of Health &amp; Medical Research of the French Government"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"O'Young","sequence":"additional","affiliation":[{"name":"Clinical Associate Prof, Rusk Institute of Rehabilitation Medicine, New York University School of Medicine"},{"name":"Visiting Prof., Peking University First Hospital, Beijing, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marilyn","family":"Jones","sequence":"additional","affiliation":[{"name":"Visiting Associate Prof, of Holistic Dentistry, International College of Acupuncture &amp; Electro-Therapeutics"},{"name":"Director, Holistic Dental Center of Houston"},{"name":"Former Assistant Professor of Chemistry, University of Houston, Texas"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew","family":"Pallos","sequence":"additional","affiliation":[{"name":"Visiting Associate Prof, of Holistic Dentistry, International College of Acupuncture &amp; Electro-Therapeutics"},{"name":"Director, Orange County Holistic Dental Clinic, Laguna Niguel, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harsha","family":"Duvvi","sequence":"additional","affiliation":[{"name":"Assistant Prof., Dept. of Family &amp; Community Medicine and Attending Physician of Neurology, New York Medical College"},{"name":"Visiting Associate Prof, of Integrative Medicine, International College of Acupuncture &amp; Electro- Therapeutics"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yasuhiro","family":"Shimotsuura","sequence":"additional","affiliation":[{"name":"Vice President, Japan Bi-Digital O-Ring Test Association (Kurume City, Fukuoka-ken, Japan)"},{"name":"Visiting Prof, of Integrative Medicine, International College of Acupuncture &amp; Electro-Therapeutics"},{"name":"Director, Shimotsuura Medical Clinic, Kurume City, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,2]]},"reference":[{"key":"e_1_3_2_2_2","unstructured":"\u201cCommon causes of Frequent urination.\u201d com. <http:\/\/www.wrongdiagnosis.com\/symptoms\/frequent_urination\/common.htm> February 24 2011."},{"key":"e_1_3_2_3_2","doi-asserted-by":"crossref","unstructured":"WetleT ScherrP BranchLG ResnickNM HarrisT EvansD TaylorJO. \u201cDifficulty with holding urine among older persons in a geographically defined community: Prevalence and correlates.\u201d Journal of the American Geriatrics Society. 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Editorial: \u201cEffects of an electrical field and its polarity on an abnormal part of the body or organ representation point associated with a diseased internal organ and its influence on the \u201dBi-Digital O-Ring Test\u201c (simple non-invasive dysfunction localization method) & drug compatibility test \u2013 Part 1.\u201d Acupuncture & Electro-Therapeutics Research. The International Journal. 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The International Journal., Vol. 10: pp. 255\u2013277,1985.","journal-title":"The International Journal.,"},{"issue":"2","key":"e_1_3_2_31_2","first-page":"65","article-title":"'\u201cBi-Digital O-Ring Test Molecular Identification and Localization Method\u2019 and its application in imaging of internal organs and malignant tumors as well as identification and localization of neurotransmitters and micro-organisms \u2014 Part 1.\u201d Acupuncture & Electro-Therapeutics Research","volume":"11","author":"Omura Y.","year":"1986","unstructured":"OmuraY. '\u201cBi-Digital O-Ring Test Molecular Identification and Localization Method\u2019 and its application in imaging of internal organs and malignant tumors as well as identification and localization of neurotransmitters and micro-organisms \u2014 Part 1.\u201d Acupuncture & Electro-Therapeutics Research. The International Journal., Vol. 11: No. 2, pp. 65\u2013100, 1986.","journal-title":"The International Journal.,"},{"key":"e_1_3_2_32_2","article-title":"Practice of \u201cBi-Digital O-Ring Test\u201d (191 printed pages in Japanese)","author":"Omura Y.","year":"1991","unstructured":"OmuraY. Practice of \u201cBi-Digital O-Ring Test\u201d (191 printed pages in Japanese), Ido-No-Nippon-Sha, Tokyo & Yokosuka, Japan, (First printed in 1986 & updated in 1991,1993,1994,1997,2000, & 2005).","journal-title":"Ido-No-Nippon-Sha"},{"key":"e_1_3_2_33_2","first-page":"139","article-title":"Interrelationship between the heart and central nervous system: localization of neuro-transmitters and imaging of their associated nuclei, including the raphe nuclei & the locus coeruleus, as well as the imaging of the heart and its representation areas in slices of the human central nervous system using the \u201dBi\u00adDigital O-Ring Test\u201c imaging method.\u201d Acupuncture & Electro-Therapeutics Research","volume":"12","author":"Omura Y.","year":"1987","unstructured":"OmuraY. \u201cInterrelationship between the heart and central nervous system: localization of neuro-transmitters and imaging of their associated nuclei, including the raphe nuclei & the locus coeruleus, as well as the imaging of the heart and its representation areas in slices of the human central nervous system using the \u201dBi\u00adDigital O-Ring Test\u201c imaging method.\u201d Acupuncture & Electro-Therapeutics Research, The International Journal., Vol. 12: pp. 139\u2013170,1987.","journal-title":"The International Journal.,"},{"key":"e_1_3_2_34_2","first-page":"53","article-title":"Meridian-like networks of internal organs, corresponding to traditional Chinese 12 main meridians and their acupuncture points as detected by the \u201dBi\u00adDigital O-Ring Test Imaging Method:\u201c Search for the corresponding internal organ of western medicine for each meridian \u2013 Part 1.\u201d Acupuncture & Electro\u00adTherapeutics Research","volume":"12","author":"Omura Y.","year":"1987","unstructured":"OmuraY. \u201cMeridian-like networks of internal organs, corresponding to traditional Chinese 12 main meridians and their acupuncture points as detected by the \u201dBi\u00adDigital O-Ring Test Imaging Method:\u201c Search for the corresponding internal organ of western medicine for each meridian \u2013 Part 1.\u201d Acupuncture & Electro\u00adTherapeutics Research. The International Journal., Vol. 12: pp. 53\u201370, 1987","journal-title":"The International Journal.,"},{"key":"e_1_3_2_35_2","first-page":"153","article-title":"Imaging of the stomach and localization of the stomach meridian & its acupuncture points in a human cadaver by the use of the indirect \u201dBi-Digital O-Ring Test Imaging Technique.\u201d Acupuncture & Electro-Theraneutics Research. The International Journal","author":"Omura Y.","year":"1988","unstructured":"OmuraY. TakeshigeC. ShimotsuuraY. SuzukiM. \u201cImaging of the stomach and localization of the stomach meridian & its acupuncture points in a human cadaver by the use of the indirect \u201dBi-Digital O-Ring Test Imaging Technique.\u201d Acupuncture & Electro-Theraneutics Research. The International Journal., 13: pp. 153\u2013164, 1988.","journal-title":"13: pp."},{"key":"e_1_3_2_36_2","first-page":"50","article-title":"Medical and Dental Problems Associated with Amalgam and the Hazards of Strong Ultraviolet Radiation used to Solidify Other Synthetic Materials as Replacements for Amalgam, and Imaging of the 4 Components of TMJ & Invisible, Hidden Pathological Findings in X-Ray Images, CT Scans, & MRI Films, and Ultrasonic Images","author":"Omura Y.","year":"1996","unstructured":"OmuraY. \u201cMedical and Dental Problems Associated with Amalgam and the Hazards of Strong Ultraviolet Radiation used to Solidify Other Synthetic Materials as Replacements for Amalgam, and Imaging of the 4 Components of TMJ & Invisible, Hidden Pathological Findings in X-Ray Images, CT Scans, & MRI Films, and Ultrasonic Images, Detected by the Bi-Digital O-Ring Test for Diagnosis and Treatment of Difficult Dental & Medical Problems.\u201d 6th Congress of the Japan Bi-Digital O-Ring Test Medical Society, 50\u201351, Tokyo University, Tokyo, Japan, 1996Aug8-10.","journal-title":"Detected by the Bi-Digital O-Ring Test for Diagnosis and Treatment of Difficult Dental & Medical Problems.\u201d 6th Congress of the Japan Bi-Digital O-Ring Test Medical Society"},{"key":"e_1_3_2_37_2","article-title":"Future Medicine O-Ring Test (341 printed pages in Japanese)","author":"Omura Y.","year":"2008","unstructured":"OmuraY. 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Kawade-Shobo-Shinsha, Tokyo, Japan, April 2009. ISBN: 978\u20134-309-27079-1","journal-title":"Tokyo"},{"key":"e_1_3_2_40_2","doi-asserted-by":"crossref","unstructured":"OmuraY. \u201cEarly Non-Invasive Cancer Screening by Detecting Levels of Integrin a5bl Oncogene C-fos Ab-2 Hg Acetylcholine Viral Infection NO D-Glucose p53 (Ab-5) & Rb (Ab-8) and a New Safe and Effective Cancer Therapy Using a Mixture of EPA & DHA as an Anti-Viral Agent & Cilantro to Remove Intracellular Mercury and \u201dSelective Drug Uptake Enhancement Method\u201c Based on the Bi-Digital O-Ring Test Evaluation.\u201d 8th Congress of the Japan Bi-Digital O-Ring Test Medical Society. 58\u201359 Showa University Tokyo Japan 1998Jul19-20.","DOI":"10.1177\/036012931998023003019"},{"key":"e_1_3_2_41_2","doi-asserted-by":"publisher","DOI":"10.3727\/036012998816356472"},{"key":"e_1_3_2_42_2","first-page":"65","article-title":"Individualized Clinical Application of Selective Drug Uptake Enhancement Method to Intractable Medical Problem Including Pain & Cancer as the Most Effective Treatment.\u201d Abstract of 10th Annual Symposium on the Bi-Digital O- Ring Test, organized by Japan Bi-Digital 0- Ring Test Medical Society","author":"Omura Y.","year":"1999","unstructured":"OmuraY. \u201cIndividualized Clinical Application of Selective Drug Uptake Enhancement Method to Intractable Medical Problem Including Pain & Cancer as the Most Effective Treatment.\u201d Abstract of 10th Annual Symposium on the Bi-Digital O- Ring Test, organized by Japan Bi-Digital 0- Ring Test Medical Society, pgs. 65\u201366, held at Tokyo University during July 23-25,1999.","journal-title":"pgs."},{"key":"e_1_3_2_43_2","first-page":"12","article-title":"Non-Invasive Diagnosis & Effective Treatment of Chronic Intractable Lower Back Pain Using the Bi-Digital O-Ring Test Resonance Phenomenon & The Selective Drug Uptake Enhancement Method.\u201d abstract published in Program and Abstract of the International Symposium: Satellite of the 9th Congress of the Pain Clinic, held in Tokyo","author":"Omura Y.","year":"2000","unstructured":"OmuraY. \u201cNon-Invasive Diagnosis & Effective Treatment of Chronic Intractable Lower Back Pain Using the Bi-Digital O-Ring Test Resonance Phenomenon & The Selective Drug Uptake Enhancement Method.\u201d abstract published in Program and Abstract of the International Symposium: Satellite of the 9th Congress of the Pain Clinic, held in Tokyo, Japan, July 12\u201313,2000, pgs. 66; the paper was subsequently published in the hardcover book Management of Pain: A World Perspective, H. 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Yuge, as part of the 9th International Symposium on Pain, organized by the International Association for the Study of Pain, by Monduzzi Editore, Bologna Italy, 2000, pgs. 65\u201374.","journal-title":"Japan"},{"key":"e_1_3_2_44_2","unstructured":"OmuraY. \u201cApplication of the Bi-Digital O-Ring Test for Diagnosis and Effective Treatment of Intractable Pain Infection & Cancer Using Selective Drug-Uptake Enhancement Methods and the Relationship Between These Intractable Problems and Harmful Environmental Electro-Magnetic Fields & Localized Deposits of Heavy Metal in the Body.\u201d 6th Congress of the Japan Bi-Digital O-Ring Test Medical Society 58\u201361 Tokyo University Tokyo Japan 1996Aug8-10."},{"key":"e_1_3_2_45_2","first-page":"1","article-title":"Effective Treatment of Intractable Medical Problems Using Accurate Organ Representation Areas of the Hand or the Cardiovascular Representations Area of the Medulla Oblongata Beneath the Occipital Area of the Skull with Drug Uptake Enhancement Methods Including Acupuncture, (+) Qi Gong, Shiatsu Massage, South Pole Magnetic Field, (-) Electrical Field and Others.\u201d Abstracts of the ICMART Symposium and 2nd Bulgarian Acupuncture Congress, l, held at the Hotel Vitosha, Sophia","author":"Omura Y.","year":"1995","unstructured":"OmuraY. \u201cEffective Treatment of Intractable Medical Problems Using Accurate Organ Representation Areas of the Hand or the Cardiovascular Representations Area of the Medulla Oblongata Beneath the Occipital Area of the Skull with Drug Uptake Enhancement Methods Including Acupuncture, (+) Qi Gong, Shiatsu Massage, South Pole Magnetic Field, (-) Electrical Field and Others.\u201d Abstracts of the ICMART Symposium and 2nd Bulgarian Acupuncture Congress, l, held at the Hotel Vitosha, Sophia, Bulgaria, June 1\u20135, 1995.","journal-title":"Bulgaria"},{"key":"e_1_3_2_46_2","first-page":"12","article-title":"Bi-Digital O-Ring Test: Application of Bi-Digital O-Ring Test for the Diagnosis of Intractable Diseases and Effective Treatment using Selective Drug Uptake Enhancement Method.\u201d (In Japanese), Fourth Symposium of the Japanese Association for Alternative, Complimentary and Traditional Medicine (JACT)","volume":"2","author":"Omura Y.","year":"2000","unstructured":"OmuraY. \u201cBi-Digital O-Ring Test: Application of Bi-Digital O-Ring Test for the Diagnosis of Intractable Diseases and Effective Treatment using Selective Drug Uptake Enhancement Method.\u201d (In Japanese), Fourth Symposium of the Japanese Association for Alternative, Complimentary and Traditional Medicine (JACT), held June 12\u201315,2000, at auditorium of Tokyo Woman's Medical College, published in the collection of the lecture texts of the \u201cFourth Symposium. 2000, of the Japanese Association for Alternative. 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