{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,28]],"date-time":"2026-04-28T10:19:35Z","timestamp":1777371575479,"version":"3.51.4"},"reference-count":86,"publisher":"SAGE Publications","issue":"3","license":[{"start":{"date-parts":[[1995,11,1]],"date-time":"1995-11-01T00:00:00Z","timestamp":815184000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Acupuncture &amp; Electro-Therapeutics Research: International Journal of Integrated Medicine"],"published-print":{"date-parts":[[1995,11]]},"abstract":"<jats:p>\n                    The authors found that antibiotics used to treat various infections often were ineffective in the presence of abnormal localized deposits of heavy metals like Hg and Pb, which were often observed to co-exist with Chlamydia trachomatis, Herpes Simplex Types I &amp; II, Cytomegalovirus(CMV), and other micro-organisms. Our earlier research revealed that despite rigorous treatment with antibiotics together with various drug uptake enhancement techniques, subjects who had been treated for Chlamydia trachomatis infections, seemingly successfully with disappearance of their symptoms, were often experiencing recurrences within several months after completion of their treatment despite taking precautions against reinfection. Careful examination of the entire body of these symptom-free patients with the Bi-Digital O-Ring Test revealed that the Chlamydia trachomatis had retreated to 3-5 hiding places with localized increase in uric acid levels: 1) sublingual caruncle, 2) a small round area in the right and\/or left axillae, 3) the genitals (Corona Glandis area of the Glans Penis at the Fossa Navicularis of the urethra in the male, and near the orifice of the urethra in the female), 4) Insulin-like Growth Factor positive horizontal lines, particularly above and below the knees, 5) the maxillary, ethmoid and frontal sinuses and the horizontal lines at the base of the nostrils (particularly small areas where Insulin-like Growth Factors exist). We found that all these areas contain Insulin-like Growth Factors I &amp; II which are reduced in the presence of infection. Even when drug uptake of antibiotics was selectively increased in these 3-5 areas by various drug uptake enhancement methods developed by the 1st author, still the infection persisted. In the spring of 1995, use of Chinese parsley for successful elimination of Hg deposits existing in various organs of the first author as the result of the decay of radioactive Thallium 201 injected for cardiac SPECT, was accidentally discovered after eating Vietnamese soup, which happened to contain Chinese parsley, also called cilantro. We also found Chinese parsley accelerates the excretion of Hg, Pb, and Al from the body through the urine. Our subjects were given a course of antibiotics (Doxycycline for Chlamydia trachomatis infection) or anti-viral agents (EPA with DHA for Herpes Family Viruses) together with Chinese parsley. Since these vegetable\/herbs were eaten, the amount of effective substance absorbed varied and some people did not like the taste of these relatively large amounts of either cooked or raw parsley or its juice, but together with effective antibiotics delivered by drug uptake enhancement methods to the infected areas, the substances worked synergisitically, rapidly reducing the generalized symptoms and infection. The micro-organisms retreated to the 3 \u223c 5 areas listed above where, with continued treatment, they were significantly reduced, but not completely eliminated. Because of these problems, a pharmaceutical company was asked to produce a Chinese parsley tablet containing a controlled amount in a highly absorbable form. When 11 subjects were treated with Doxycycline for Chlamydia trachomatis infection, or anti-viral agents (EPA with DHA) for Herpes Family Viruses, drug uptake enhancement methods to selectively increase delivery of the drugs to the affected areas, and Chinese parsley tablets to remove the heavy metal deposits, the last traces of the infections and clinical symptoms disappeared completely. Therefore we hypothesized that the infectious micro-organisms mentioned above, somehow utilize the Hg or Pb to protect themselves from what would otherwise be effective antibiotics, and\/or that heavy metal deposits in some way make antibiotics ineffective. Since the micro-organisms retreat to areas in which Insulin-like Growth Factors I &amp; II normally exist, they may be utilizing them for their own growth and multiplication. These phenomena may be related to die development of drug resistance by the micro- organisms. Based on our Bi-Digital O-Ring Test study, we considered at least 12 different diseases which involve localized deposits of various metals with co-existing variety of infections. Among them was cancer, and as the first author's previous study in the late 1980s indicated, various cancer and pre-cancer cell nuclei contained Hg along with 4 other parameters. Namely, in pre-cancer and cancer tissues the following 5 parameters coexist: 1) marked presence of Oncogene C-fos Ab\n                    <jats:sub>2<\/jats:sub>\n                    , 2) marked presence of Integrin \u03b1\n                    <jats:sub>5<\/jats:sub>\n                    \u03b2\n                    <jats:sub>1<\/jats:sub>\n                    , 3) presence of significant Hg deposits, 4) presence of virus, 5) absence of Acetylcholine. Since with the use of the anti viral agent and Chinese parsley the above parameters returned to almost normal on the first author's upper arm where the pre-cancerous cells had been found, we are currently giving a number of volunteers, referred by physicians, (with various types of cancer with metastasis confirmed by histological examination) a combination of 2 dietary supplements: EPA with DHA as an anti-viral agent, and Chinese parsley tablets to remove the localized Hg deposits from the cell nuclei. Various drug uptake enhancement methods are included in this treatment. This preliminary study has shown potential beneficial effects in reducing of cancerous and metastatic tumors, and their associated pain.\n                  <\/jats:p>","DOI":"10.3727\/036012995816357014","type":"journal-article","created":{"date-parts":[[2015,11,3]],"date-time":"2015-11-03T00:29:30Z","timestamp":1446510570000},"page":"195-229","source":"Crossref","is-referenced-by-count":29,"title":["Role of Mercury(Hg) in Resistant Infections &amp; Effective Treatment of Chlamydia Trachomatis and Herpes Family Viral Infections (and Potential Treatment for Cancer) by Removing Localized Hg Deposits with Chinese Parsley and Delivering Effective Antibiotics Using Various Drug Uptake Enhancement Methods"],"prefix":"10.1177","volume":"20","author":[{"given":"Yoshiaki","family":"Omura","sequence":"first","affiliation":[{"name":"Medical Research, Heart Disease Research Foundation, New York; President, International College of Acupuncture &amp; Electro-Therapeutics, New York;"},{"name":"Dept. of Electrical Engineering, Manhattan College, Bronx, N.Y.; Prof., Dept. of Non-Orthodox Medicine, Ukrainian National Medical University, Kiev;"},{"name":"Dept. of Physiology, Showa University School of Medicine, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sandra L.","family":"Beckman","sequence":"additional","affiliation":[{"name":"The Soifer Center for Learning &amp;Child Development, White Plains, New York, U.S.A. Adjunct Assistant Prof., Dept. of Speech, Brooklyn College, Brooklyn, New York."}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"179","published-online":{"date-parts":[[1995,11]]},"reference":[{"issue":"1","key":"e_1_3_2_2_2","first-page":"21","article-title":"Application of Intensified (+) Qi Gong Energy","volume":"20","author":"Omura Y.","year":"1995","unstructured":"OmuraY. & BeckmanS. \u201cApplication of Intensified (+) Qi Gong Energy, (-) Electrical Field, (S) Magnetic Field, Electrical Pulses (1-2 Pulses\/sec.), Strong Shiatsu Massage or Acupuncture on the Accurate Organ Representation Areas of the Hands to Improve Circulation and Enhance Drug Uptake in Pathological Organs; Clinical Applications with Special Emphasis on the \u2018Chlamydia - (Lyme) - Uric Acid Syndrome\u2019 and \u2018Chlamydia - (Cytomegalovirus) - Uric Acid Syndrome',\u201d Acupuncture & Electro-Therapeutics Research, the International Journal. 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The International Journal., Vol. 19: pp. 39\u201363, 1994.","journal-title":"The International Journal."},{"key":"e_1_3_2_5_2","article-title":"Practice of \u201cBi-Digital O-Ring Test\u201d (in Japanese)","author":"Omura Y.","year":"1995","unstructured":"OmuraY. Practice of \u201cBi-Digital O-Ring Test\u201d (in Japanese), Ido-No-Nippon-Sha, Tokyo & Yokosuka, Japan, 4th Ed., 2nd printing 1995.","journal-title":"Ido-No-Nippon-Sha"},{"key":"e_1_3_2_6_2","doi-asserted-by":"publisher","DOI":"10.3727\/036012994816357286"},{"key":"e_1_3_2_7_2","first-page":"14","article-title":"Imaging & Evaluation of the 4 Components (Fossa","author":"Omura Y.","year":"1994","unstructured":"OmuraY. 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