{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T23:04:38Z","timestamp":1791414278294,"version":"4.3.3"},"reference-count":26,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2011,3,1]],"date-time":"2011-03-01T00:00:00Z","timestamp":1298937600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perit Dial Int"],"published-print":{"date-parts":[[2011,3]]},"abstract":"<jats:sec>\n                    <jats:title>Objective<\/jats:title>\n                    <jats:p>There are various causes of halitosis, one of which is chronic renal failure. The objective of this study was to investigate halitosis levels in end-stage renal disease (ESRD) patients before and after peritoneal dialysis (PD) therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>42 subjects with ESRD were included in this study. The presence of halitosis was assessed using an organoleptic measurement and compared with blood urea nitrogen (BUN) levels and salivary flow rates. Decayed, missing, and filled teeth (DMFT) index and Community Periodontal Index (CPI) were calculated. All measurements were done before and after patients had received 3 months of PD therapy.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Mean serum BUN level was found to be lower (46.05 \u00b1 13.30 vs 91.24 \u00b1 31.28 mg\/dL), salivary flow rate higher (0.34 \u00b1 0.07 vs 0.26 \u00b1 0.04 mL\/minute), and halitosis level lower (2.39 \u00b1 0.60 vs 3.90 \u00b1 0.37) at the end of 3 months of PD therapy than at the beginning of PD therapy. There was no significant difference in CPI or DMFT index before and after PD therapy (p &gt; 0.05). There was statistically significant positive correlation between the presence of halitosis and BUN levels ( r = 0.702, p = 0.001 before PD; r = 0.45, p = 0.002 after PD) and a negative correlation between the presence of halitosis and salivary flow rates ( r = -0.69, p = 0.000 before PD; r = -0.37, p = 0.01 after PD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>High BUN levels and low salivary flow rates were found to be associated with halitosis. PD may play an important role in decreasing the level of halitosis in ESRD patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3747\/pdi.2009.00089","type":"journal-article","created":{"date-parts":[[2010,3,25]],"date-time":"2010-03-25T20:36:26Z","timestamp":1269549386000},"page":"168-172","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":16,"title":["Does Peritoneal Dialysis Affect Halitosis in Patients with End-Stage Renal Disease?"],"prefix":"10.1177","volume":"31","author":[{"given":"Mustafa","family":"Keles","sequence":"first","affiliation":[{"name":"Department of Nephrology, Faculty of Medicine, Erzurum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ummuhan","family":"Tozoglu","sequence":"additional","affiliation":[{"name":"Departments of Oral Diagnosis and Radiology, Erzurum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abdullah","family":"Uyanik","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Faculty of Medicine, Erzurum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Abubekir","family":"Eltas","sequence":"additional","affiliation":[{"name":"Periodontology, Erzurum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yusuf Ziya","family":"Bayindir","sequence":"additional","affiliation":[{"name":"Operative Dentistry, Faculty of Dentistry, Atat\u00fcrk University, Erzurum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ramazan","family":"Cetinkaya","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Faculty of Medicine, Erzurum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Osman Murat","family":"Bilge","sequence":"additional","affiliation":[{"name":"Departments of Oral Diagnosis and Radiology, Erzurum, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2011,3,1]]},"reference":[{"key":"bibr1-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.14219\/jada.archive.2003.0244"},{"key":"bibr2-pdi.2009.00089","first-page":"1281","volume":"126","author":"Attia E.L.","year":"1982","journal-title":"Can Med Assoc J"},{"key":"bibr3-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2007.01116.x"},{"key":"bibr4-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0765.1992.tb01673.x"},{"key":"bibr5-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1902\/jop.1992.63.9.783"},{"key":"bibr6-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.1.79"},{"key":"bibr7-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1902\/jop.2001.72.1.74"},{"key":"bibr8-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-051x.2001.028005494.x"},{"key":"bibr9-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1002\/j.1875-595X.2002.tb00932.x"},{"key":"bibr10-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1046\/j.0303-6979.2003.00407.x"},{"key":"bibr11-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1111\/j.1601-0825.2005.01083.x"},{"key":"bibr12-pdi.2009.00089","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-051X.2005.00862.x"},{"key":"bibr13-pdi.2009.00089","first-page":"134","volume":"25","author":"Akcan A.B.","year":"2008","journal-title":"New Journal of Medicine"},{"key":"bibr14-pdi.2009.00089","first-page":"7","volume":"3","author":"Rosenberg M.","year":"1990","journal-title":"Univ Tor Dent J"},{"issue":"3","key":"bibr15-pdi.2009.00089","first-page":"46","volume":"26","author":"Weinberg M.","year":"2001","journal-title":"US Pharmacist"},{"key":"bibr16-pdi.2009.00089","unstructured":"NevilleB.W., DammD.D., AllenC.M., BouquotJ.E., eds. 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