{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,22]],"date-time":"2026-09-22T20:20:18Z","timestamp":1790108418647,"version":"4.0.1"},"reference-count":40,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perit Dial Int"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>Peritonitis is a major complication and the main cause of peritoneal dialysis (PD) failure. The aim of the present study was to evaluate peritonitis risk factors and its prevention with a new peritoneal educational program (NPEP).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>We performed a retrospective analysis of a cohort of chronic PD patients, older than 16 years, who began PD in the period 1 January 1999 to 31 December 2015 at a Uruguayan PD center, with follow-up until 31 December 2016.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>The population included 222 cases (219 patients, 128 men), median age 59 (interquartile range [IQR] 47.0 \u2013 72.0) years, median time on PD 17.5 (IQR 6.0 \u2013 36.2) months. Ninety-five patients suffered 1 or more episodes of peritonitis, and they had been on PD for a longer period and had nasal-positive culture more frequently. A NPEP started in September 2008; patients who trained with it, as well as younger patients, had longer peritonitis-free survival. After the NPEP, global peritonitis rates decreased significantly (from 0.48 to 0.29 episodes\/patient-year, respectively), particularly gram-positive bacteria and Staphylococcus aureus \/ coagulase-negative (CoNS) (from 0.26 to 0.12 and 0.21 to 0.07 episodes\/patient-year, respectively). In the multivariate Cox analysis of peritonitis risk factors, survival to first peritonitis was significantly associated only with age (hazard ratio [HR] 1.024, 95% confidence interval [CI] 1.007 \u2013 1.397, p = 0.007) and the NPEP (HR 0.600, 95% CI 0.394 \u2013 0.913, p = 0.017).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusion<\/jats:title>\n                    <jats:p>A multidisciplinary peritoneal educational program may improve peritonitis rates, independently of other risk factors.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3747\/pdi.2017.00287","type":"journal-article","created":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T22:14:21Z","timestamp":1537913661000},"page":"119-125","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":29,"title":["Risk Factors and Prevention of Peritoneal Dialysis-Related Peritonitis"],"prefix":"10.1177","volume":"39","author":[{"given":"Liliana","family":"Gadola","sequence":"first","affiliation":[{"name":"Centro de Di\u00e1lisis Peritoneal, CASMU IAMPP, Montevideo, Uruguay"},{"name":"Centro de Nefrolog\u00eda, Universidad de la Rep\u00fablica, Montevideo, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carla","family":"Poggi","sequence":"additional","affiliation":[{"name":"Centro de Di\u00e1lisis Peritoneal, CASMU IAMPP, Montevideo, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Patricia","family":"Dominguez","sequence":"additional","affiliation":[{"name":"Centro de Di\u00e1lisis Peritoneal, CASMU IAMPP, Montevideo, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar\u00eda V.","family":"Poggio","sequence":"additional","affiliation":[{"name":"Centro de Di\u00e1lisis Peritoneal, CASMU IAMPP, Montevideo, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eliana","family":"Lungo","sequence":"additional","affiliation":[{"name":"Centro de Di\u00e1lisis Peritoneal, CASMU IAMPP, Montevideo, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Cardozo","sequence":"additional","affiliation":[{"name":"Centro de Di\u00e1lisis Peritoneal, CASMU IAMPP, Montevideo, Uruguay"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,3,1]]},"reference":[{"key":"bibr1-pdi.2017.00287","doi-asserted-by":"publisher","DOI":"10.1177\/089686080502500203"},{"key":"bibr2-pdi.2017.00287","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2010.00049"},{"key":"bibr3-pdi.2017.00287","doi-asserted-by":"publisher","DOI":"10.1177\/089686080802800502"},{"key":"bibr4-pdi.2017.00287","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2016.00078"},{"key":"bibr5-pdi.2017.00287","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2010.00185"},{"key":"bibr6-pdi.2017.00287","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.02.025"},{"key":"bibr7-pdi.2017.00287","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001915"},{"key":"bibr8-pdi.2017.00287","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(04)00941-2"},{"issue":"3","key":"bibr9-pdi.2017.00287","first-page":"166","volume":"32","author":"Gadola 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