{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T18:43:54Z","timestamp":1789929834417,"version":"4.0.1"},"reference-count":16,"publisher":"SAGE Publications","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perit Dial Int"],"published-print":{"date-parts":[[2019,1]]},"abstract":"<jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>Cognitive impairment is common among patients on peritoneal dialysis (PD). We hypothesize that cognitive impairment has a negative impact on the outcome of patients on PD, especially with regard to peritonitis.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This was a single-center 2-year prospective cohort study involving 206 patients at 1 PD unit. Cognitive impairment was defined by the latest Hong Kong Montreal Cognitive Assessment Score (HK-MoCA) multiple cut-offs as determined by age and years of education. Eighty percent of patients had come back for interval HK-MoCA. The HK-MoCA was performed at baseline and after 1 year on PD. Potential risk factors for cognitive impairment and peritonitis were studied separately for the first and second year.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>For cognitive impairment at baseline, multivariate analyses showed that age (odds ratio [OR] 1.003, 95% confidence interval [CI] 1.003 \u2013 1.065, p = 0.03), female sex (OR 3.57, 95% CI 1.60 \u2013 7.97, p = 0.002), peripheral vascular disease (PVD) (OR 3.46, 95% CI 1.33 \u2013 9.01, p = 0.01), and hemoglobin level (OR 0.60, 95% CI 0.43 \u2013 0.84, p = 0.003) were statistically significant factors. For cognitive impairment at 1 year, multivariate analyses showed that age (OR 1.07, 95% CI 1.02 \u2013 1.012, p = 0.007), female sex (OR 5.87, 95% CI 1.86 \u2013 18.5, p = 0.003), and PVD (OR 3.68, 95% CI 1.07 \u2013 12.84, p = 0.04) were statistically significant independent factors for cognitive impairment at 1 year. For self-care PD patients in the second year, patients with cognitive impairment had a higher rate of peritonitis and proportionately more patients suffered from both peritonitis and exit-site infection than non-cognitively impaired patients in the second year (0.50 vs 0.27 episodes per year, p = 0.048; 25% vs 7.2%, p = 0.049). Logistic regression showed that only HK-MoCA-defined cognitive impairment and HK-MoCA scores at 1 year were factors predicting peritonitis (risk ratio [RR] 3.2 [95% CI 1.03 \u2013 9.95], p = 0.04 and RR 0.92 [95% CI 0.86 \u2013 0.995], p = 0.04 respectively).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In summary, increasing age, female sex, anemia, and presence of PVD are risk factors for cognitive impairment in PD patients. Self-care PD with cognitive impairment at 1 year has a higher risk for PD-related peritonitis in the second year. Interval HK-MoCA assessment is recommended to detect cognitive impairment in our local PD patients.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3747\/pdi.2018.00048","type":"journal-article","created":{"date-parts":[[2018,8,7]],"date-time":"2018-08-07T12:27:16Z","timestamp":1533644836000},"page":"51-58","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":15,"title":["Self-Care Peritoneal Dialysis Patients with Cognitive Impairment Have a Higher Risk of Peritonitis in the Second Year"],"prefix":"10.1177","volume":"39","author":[{"given":"Yat-fung","family":"Shea","sequence":"first","affiliation":[{"name":"Division of Geriatrics, Department of Medicine, LKS Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mi-suen Connie","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Occupational Therapy, Queen Mary Hospital, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ming-yee Maggie","family":"Mok","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, LKS Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Man-fai","family":"Lam","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, LKS Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leung-wing","family":"Chu","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Department of Medicine, LKS Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Felix Hon-wai","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Geriatrics, Department of Medicine, LKS Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tak Mao","family":"Chan","sequence":"additional","affiliation":[{"name":"Division of Nephrology, Department of Medicine, LKS Faculty of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,1,1]]},"reference":[{"key":"bibr1-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1159\/000439193"},{"key":"bibr2-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2014.02.025"},{"key":"bibr3-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2014.00247"},{"key":"bibr4-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2015.06.025"},{"key":"bibr5-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1007\/s10157-015-1127-x"},{"key":"bibr6-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1161\/STROKEAHA.115.011226"},{"key":"bibr7-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1016\/0895-4356(94)90129-5"},{"key":"bibr8-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.3747\/pdi.2016.00078"},{"key":"bibr9-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1001\/archneurol.2009.266"},{"key":"bibr10-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2015.131"},{"key":"bibr11-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1111\/psyg.12053"},{"key":"bibr12-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1159\/000452603"},{"key":"bibr13-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0183965"},{"key":"bibr14-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1016\/j.hkjn.2013.03.005"},{"key":"bibr15-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(03)00661-9"},{"key":"bibr16-pdi.2018.00048","doi-asserted-by":"publisher","DOI":"10.1111\/nep.12970"}],"container-title":["Peritoneal Dialysis International: Journal of the International Society for Peritoneal Dialysis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3747\/pdi.2018.00048","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/full-xml\/10.3747\/pdi.2018.00048","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/journals.sagepub.com\/doi\/pdf\/10.3747\/pdi.2018.00048","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T05:25:12Z","timestamp":1777613112000},"score":1,"resource":{"primary":{"URL":"https:\/\/journals.sagepub.com\/doi\/10.3747\/pdi.2018.00048"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":16,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.3747\/pdi.2018.00048"],"URL":"https:\/\/doi.org\/10.3747\/pdi.2018.00048","relation":{},"ISSN":["0896-8608","1718-4304"],"issn-type":[{"value":"0896-8608","type":"print"},{"value":"1718-4304","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]}}}