{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,12]],"date-time":"2026-10-12T18:56:59Z","timestamp":1791831419173,"version":"4.3.4"},"reference-count":19,"publisher":"SAGE Publications","issue":"2","license":[{"start":{"date-parts":[[2019,3,1]],"date-time":"2019-03-01T00:00:00Z","timestamp":1551398400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perit Dial Int"],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The incidence of elderly patients receiving peritoneal dialysis (PD) has increased. This study aimed to examine the clinical presentation and outcomes of peritonitis in elderly PD patients compared with younger PD patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>This single-center, retrospective, observational cohort study included all adult PD patients who developed peritonitis between January 2011 and December 2014. Elderly was defined as \u2265 65 years old at PD initiation. The primary outcome was medical cure, defined as a peritonitis episode cured by antibiotics without being complicated by catheter removal, transfer to hemodialysis (HD), relapsing peritonitis, or death. The secondary outcomes were clinical manifestations (fever, cloudy dialysate) and complications (catheter removal, transfer to HD, relapse, hospitalization, and mortality). Peritonitis outcomes were compared using multivariable logistic regression.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Overall, 377 peritonitis episodes occurred in 247 patients. Of these, 126 episodes occurred in 79 elderly patients and 251 episodes occurred in 168 younger patients. Baseline demographic data were comparable between the 2 groups, except that elderly patients were significantly more likely to have diabetes mellitus (66% vs 46%), diabetic nephropathy (55% vs 39%), and a lower serum albumin than younger patients. Medical cure was comparable between the 2 groups (71% vs 72%, respectively, p = 0.67, adjusted odds ratio [AOR] 0.89, 95% confidence interval [CI]: 0.52 \u2013 1.53). Compared with younger patients, elderly patients experiencing peritonitis had lower odds of fever (OR 0.53, 95% CI: 0.30 \u2013 0.94), cloudy dialysate (OR 0.45, 95% CI: 0.23 \u2013 0.88), and catheter removal (AOR 0.50, 95% CI: 0.26 \u2013 0.98), but similar odds of transfer to HD (AOR 0.70, 95% CI: 0.32 \u2013 1.51), relapse (AOR 1.57, 95% CI: 0.46 \u2013 5.40), hospitalization (AOR 1.55, 95% CI: 0.52 \u2013 4.56), and all-cause mortality (AOR 1.88, 95% CI: 0.83 \u2013 4.26).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>Compared with younger patients, elderly PD patients with peritonitis achieved similar medical cure rates, a lower catheter removal rate, and comparable rates of HD transfer, relapse, hospitalization, and death. Elderly PD patients experiencing peritonitis were less likely to present with fever or cloudy dialysate.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3747\/pdi.2018.00056","type":"journal-article","created":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T22:15:17Z","timestamp":1537913717000},"page":"163-168","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":21,"title":["Comparison of Clinical Presentation and Outcomes of Peritonitis in the Elderly and Younger Peritoneal Dialysis Patients"],"prefix":"10.1177","volume":"39","author":[{"given":"Htay","family":"Htay","sequence":"first","affiliation":[{"name":"Department of Renal Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jun Jie Benjamin","family":"Seng","sequence":"additional","affiliation":[{"name":"Department of Medicine, Duke-NUS Medical School, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei Hui Amanda","family":"Yong","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suh Chien","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sin Yan","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Choong Meng","family":"Chan","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mui Hian","family":"Sim","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Johnson","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Princess Alexandra Hospital, Australia"},{"name":"Australasian Kidney Trials Network, School of Medicine, University of Queensland, Brisbane, Australia"},{"name":"Australia and New Zealand Dialysis and Transplant (ANZDATA) Registry"},{"name":"Translational Research Institute, Brisbane, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marjorie Wai Yin","family":"Foo","sequence":"additional","affiliation":[{"name":"Department of Renal Medicine, Singapore General Hospital, Singapore"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,3,1]]},"reference":[{"key":"bibr1-pdi.2018.00056","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2011060607"},{"key":"bibr2-pdi.2018.00056","doi-asserted-by":"publisher","DOI":"10.1038\/nrneph.2016.181"},{"key":"bibr3-pdi.2018.00056","unstructured":"Ageing | United Nations. 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Special section: aging and infectious diseases. Fever in the Elderly. [Online.] Available from: https:\/\/pdfs.semantic-scholar.org\/8796\/d2faccaa8ab703d5ce0f3e3fa7d68a715c2d.pdf. 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