{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T16:15:08Z","timestamp":1791303308355,"version":"4.1.0"},"reference-count":42,"publisher":"SAGE Publications","issue":"6","license":[{"start":{"date-parts":[[2019,11,1]],"date-time":"2019-11-01T00:00:00Z","timestamp":1572566400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/journals.sagepub.com\/page\/policies\/text-and-data-mining-license"}],"content-domain":{"domain":["journals.sagepub.com"],"crossmark-restriction":true},"short-container-title":["Perit Dial Int"],"published-print":{"date-parts":[[2019,11]]},"abstract":"<jats:sec>\n                    <jats:title>Background<\/jats:title>\n                    <jats:p>The optimal treatment for managing anemia in peritoneal dialysis (PD) patients and best clinical practices are not completely understood. We sought to characterize international variations in anemia measures and management among PD patients.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>The Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) enrolled adult PD patients from 6 countries from 2014 to 2017. Hemoglobin (Hb), ferritin levels, and transferrin saturation (TSAT), as well as erythropoiesis stimulating agents (ESAs) and iron use were compared cross-sectionally at study enrollment in Australia and New Zealand (A\/NZ), Canada, Japan, the United Kingdom (UK), and the United States (US).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Among 3,603 PD patients from 193 facilities, mean Hb ranged from 11.0 \u2013 11.3 g\/dL across countries. The majority of patients (range 53% \u2013 59%) had Hb 10 \u2013 11.9 g\/dL, with 4% \u2013 12% patients \u2265 13 g\/dL and 16% \u2013 23% &lt; 10 g\/dL. Use of ESAs was higher in Japan (94% of patients) than elsewhere (66% \u2013 79% of patients). In the US, 63% of patients had a ferritin level &gt; 500 ng\/mL, compared with 5% \u2013 38% in other countries. In the US and Japan, 87% \u2013 89% of PD patients had TSAT \u2265 20%, compared with 73% \u2013 76% in other countries. Intravenous (IV) iron use within 4 months of enrollment was higher in the US (55% of patients) than elsewhere (6% \u2013 17% patients).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>In this largest international observational study of anemia and anemia management in patients receiving PD, comparable Hb levels across countries were observed but with notable differences in ESA and iron use. Peritoneal dialysis patients in the US have higher ferritin levels and higher IV iron use than other countries.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3747\/pdi.2018.00249","type":"journal-article","created":{"date-parts":[[2019,10,3]],"date-time":"2019-10-03T21:34:11Z","timestamp":1570138451000},"page":"539-546","update-policy":"https:\/\/doi.org\/10.1177\/sage-journals-update-policy","source":"Crossref","is-referenced-by-count":35,"title":["International Anemia Prevalence and Management in Peritoneal Dialysis Patients"],"prefix":"10.1177","volume":"39","author":[{"given":"Rachel L.","family":"Perlman","sequence":"first","affiliation":[{"name":"University of Michigan Health Center, Ann Arbor, MI, USA"},{"name":"Arbor Research Collaborative for Health, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junhui","family":"Zhao","sequence":"additional","affiliation":[{"name":"Arbor Research Collaborative for Health, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas S.","family":"Fuller","sequence":"additional","affiliation":[{"name":"Arbor Research Collaborative for Health, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Bieber","sequence":"additional","affiliation":[{"name":"Arbor Research Collaborative for Health, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun","family":"Li","sequence":"additional","affiliation":[{"name":"University of Michigan, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald L.","family":"Pisoni","sequence":"additional","affiliation":[{"name":"Arbor Research Collaborative for Health, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bruce M.","family":"Robinson","sequence":"additional","affiliation":[{"name":"Arbor Research Collaborative for Health, Ann Arbor, MI, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David W.","family":"Johnson","sequence":"additional","affiliation":[{"name":"University of Queensland at Princess Alexandra Hospital, Brisbane, QLD, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hideki","family":"Kawanishi","sequence":"additional","affiliation":[{"name":"Tsuchiya General Hospital, Hiroshima, Japan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Simon J.","family":"Davies","sequence":"additional","affiliation":[{"name":"Keele University, Keele, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Martin J.","family":"Schreiber","sequence":"additional","affiliation":[{"name":"DaVita HealthCare Partners Inc., Denver, CO, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Perl","sequence":"additional","affiliation":[{"name":"St. Michael's Hospital, University of Toronto, Toronto, ON, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"179","published-online":{"date-parts":[[2019,11,1]]},"reference":[{"key":"bibr1-pdi.2018.00249","doi-asserted-by":"publisher","DOI":"10.1016\/S0272-6386(88)80150-1"},{"issue":"4","key":"bibr2-pdi.2018.00249","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1038\/kisup.2012.37","volume":"2","author":"Kidney Disease: Improving Global Outcomes (KDIGO) Anemia Work Group","year":"2012","journal-title":"Kidney Int Suppl"},{"key":"bibr3-pdi.2018.00249","doi-asserted-by":"crossref","unstructured":"YamamotoH., NishiS., TomoT., MasakaneI., SaitoK., NangakuM. 2015 Japanese Society for Dialysis Therapy. 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