{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,24]],"date-time":"2025-07-24T11:42:22Z","timestamp":1753357342496},"reference-count":12,"publisher":"Baishideng Publishing Group Inc.","issue":"48","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2008]]},"DOI":"10.3748\/wjg.14.7397","type":"journal-article","created":{"date-parts":[[2008,12,26]],"date-time":"2008-12-26T01:22:03Z","timestamp":1230254523000},"page":"7397","source":"Crossref","is-referenced-by-count":4,"title":["Peutz-Jeghers syndrome with small intestinal malignancy and cervical carcinoma"],"prefix":"10.3748","volume":"14","author":[{"given":"Lian-Jie","family":"Li","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhi-Qing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bao-Ping","family":"Wu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Giardiello FM, Trimbath JD. Peutz-Jeghers syndrome and management recommendations. Clin Gastroenterol Hepatol 2006;4:408-415.","DOI":"10.1016\/j.cgh.2005.11.005"},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Giardiello FM, Brensinger JD, Tersmette AC, Goodman SN, Petersen GM, Booker SV, Cruz-Correa M, Offerhaus JA. Very high risk of cancer in familial Peutz-Jeghers syndrome. Gastroenterology 2000;119:1447-1453.","DOI":"10.1053\/gast.2000.20228"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Young RH, Welch WR, Dickersin GR, Scully RE. Ovarian sex cord tumor with annular tubules: review of 74 cases including 27 with Peutz-Jeghers syndrome and four with adenoma malignum of the cervix. Cancer 1982;50:1384-1402.","DOI":"10.1002\/1097-0142(19821001)50:7<1384::AID-CNCR2820500726>3.0.CO;2-5"},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Chen KT. Female genital tract tumors in Peutz-Jeghers syndrome. Hum Pathol 1986;17:858-861.","DOI":"10.1016\/S0046-8177(86)80208-8"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Baas AF, Smit L, Clevers H. LKB1 tumor suppressor protein: PARtaker in cell polarity. Trends Cell Biol 2004;14:312-319.","DOI":"10.1016\/j.tcb.2004.04.001"},{"key":"ref6","unstructured":"Miyaki M, Iijima T, Hosono K, Ishii R, Yasuno M, Mori T, Toi M, Hishima T, Shitara N, Tamura K. Somatic mutations of LKB1 and beta-catenin genes in gastrointestinal polyps from patients with Peutz-Jeghers syndrome. Cancer Res 2000;60:6311-6313."},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Wang ZJ, Ellis I, Zauber P, Iwama T, Marchese C, Talbot I, Xue WH, Yan ZY, Tomlinson I. Allelic imbalance at the LKB1 (STK11) locus in tumours from patients with Peutz-Jeghers' syndrome provides evidence for a hamartoma-(adenoma)-carcinoma sequence. J Pathol 1999;188:9-13.","DOI":"10.1002\/(SICI)1096-9896(199905)188:1<9::AID-PATH326>3.0.CO;2-E"},{"key":"ref8","unstructured":"Gruber SB, Entius MM, Petersen GM, Laken SJ, Longo PA, Boyer R, Levin AM, Mujumdar UJ, Trent JM, Kinzler KW. Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome. Cancer Res 1998;58:5267-5270."},{"key":"ref9","unstructured":"Miyoshi H, Nakau M, Ishikawa TO, Seldin MF, Oshima M, Taketo MM. Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice. Cancer Res 2002;62:2261-2266."},{"key":"ref10","doi-asserted-by":"crossref","unstructured":"Jansen M, de Leng WW, Baas AF, Myoshi H, Mathus-Vliegen L, Taketo MM, Clevers H, Giardiello FM, Offerhaus GJ. Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis. Gut 2006;55:1-5.","DOI":"10.1136\/gut.2005.069062"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Clevers H. Stem cells, asymmetric division and cancer. Nat Genet 2005;37:1027-1028.","DOI":"10.1038\/ng1005-1027"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Katajisto P, Vaahtomeri K, Ekman N, Ventel&auml; E, Ristim&auml;ki A, Bardeesy N, Feil R, DePinho RA, M&auml;kel&auml; TP. LKB1 signaling in mesenchymal cells required for suppression of gastrointestinal polyposis. Nat Genet 2008;40:455-459.","DOI":"10.1038\/ng.98"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v14\/i48\/7397.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,16]],"date-time":"2019-05-16T18:02:41Z","timestamp":1558029761000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v14\/i48\/7397.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008]]},"references-count":12,"journal-issue":{"issue":"48","published-print":{"date-parts":[[2008]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.14.7397","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2008]]}}}