{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T03:02:15Z","timestamp":1761102135604},"reference-count":54,"publisher":"Baishideng Publishing Group Inc.","issue":"11","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2005]]},"DOI":"10.3748\/wjg.v11.i11.1673","type":"journal-article","created":{"date-parts":[[2014,12,21]],"date-time":"2014-12-21T21:50:51Z","timestamp":1419198651000},"page":"1673","source":"Crossref","is-referenced-by-count":6,"title":["Clinicopathological and molecular genetic analysis of HNPCC in China"],"prefix":"10.3748","volume":"11","author":[{"given":"Ding-Cun","family":"Luo","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"crossref","unstructured":"Lynch HT, Smyrk TC, Watson P, Lanspa SJ, Lynch JF, Lynch PM, Cavalieri RJ, Boland CR. Genetics, natural history, tumor spectrum, and pathology of hereditary nonpolyposis colorectal cancer: an updated review. Gastroenterology 1993;104:1535-1549.","DOI":"10.1016\/0016-5085(93)90368-M"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.50.1.43"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/87.15.1114"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1055\/s-2002-33419"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198709000-00007"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/BF02053699"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.jjco.a023244"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1126\/science.8484120"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90330-S"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90546-3"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1038\/371075a0"},{"key":"ref12","unstructured":"Nystr&ouml;m-Lahti M, Parsons R, Sistonen P, Pylkk&auml;nen L, Aaltonen LA, Leach FS, Hamilton SR, Watson P, Bronson E, Fusaro R. Mismatch repair genes on chromosomes 2p and 3p account for a major share of hereditary nonpolyposis colorectal cancer families evaluable by linkage. Am J Hum Genet 1994;55:659-665."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1126\/science.8128251"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/368258a0"},{"key":"ref15","unstructured":"Wijnen J, Vasen H, Khan PM, Menko FH, van der Klift H, van Leeuwen C, van den Broek M, van Leeuwen-Cornelisse I, Nagengast F, Meijers-Heijboer A. Seven new mutations in hMSH2, an HNPCC gene, identified by denaturing gradient-gel electrophoresis. Am J Hum Genet 1995;56:1060-1066."},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1002\/jso.10064"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/S0165-022X(00)00148-2"},{"key":"ref18","unstructured":"Wahlberg SS, Schmeits J, Thomas G, Loda M, Garber J, Syngal S, Kolodner RD, Fox E. Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families. Cancer Res 2002;62:3485-3492."},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Cai SJ, Xu Y, Cai GX, Lian P, Guan ZQ, Mo SJ, Sun MH, Cai Q, Shi DR. Clinical characteristics and diagnosis of patients with hereditary nonpolyposis colorectal cancer. World J Gastroenterol 2003;9:284-287.","DOI":"10.3748\/wjg.v9.i2.284"},{"key":"ref20","unstructured":"Mo SJ, Cai H, Cai SJ. Hereditary non-polyposis colorectal cancer: A report of 10 Chinese families. Zhonghua Xiaohua Zazhi 1996;16:326-328."},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Bocker T, R&uuml;schoff J, Fishel R. Molecular diagnostics of cancer predisposition: hereditary non-polyposis colorectal carcinoma and mismatch repair defects. Biochim Biophys Acta 1999;1423:O1-O10.","DOI":"10.1016\/S0304-419X(99)00008-6"},{"key":"ref22","unstructured":"Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58:5248-5257."},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Gebert J, Sun M, Ridder R, Hinz U, Lehnert T, M&ouml;ller P, Schackert HK, Herfarth C, von Knebel Doeberitz M. Molecular profiling of sporadic colorectal tumors by microsatellite analysis. Int J Oncol 2000;16:169-179.","DOI":"10.3892\/ijo.16.1.169"},{"key":"ref24","unstructured":"Wei SC, Wang MH, Shieh MC, Wang CY, Wong JM. Clinical characteristics of Taiwanese hereditary non-polyposis colorectal cancer kindreds. J Formos Med Assoc 2002;101:206-209."},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1007\/BF02235180"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19990118)80:2&lt;183::AID-IJC4&gt;3.0.CO;2-W"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19960915)78:6&lt;1149::AID-CNCR1&gt;3.0.CO;2-5"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2388(200006)18:4&lt;305::AID-SSU5&gt;3.0.CO;2-A"},{"key":"ref29","unstructured":"Bernstein IT, Bisgaard ML, Myrh&oslash;j T. Registration of hereditary non-polyposis colorectal cancer. Ugeskr Laeger 1999;161:6174-6178."},{"key":"ref30","unstructured":"Ponz de Leon M, Benatti P, Percesepe A, Rossi G, Viel A, Santarosa M, Pedroni M, Roncucci L. Clinical and molecular diagnosis of hereditary non-polyposis colorectal cancer: problems and pitfalls in an extended pedigree. Ital J Gastroenterol Hepatol 1999;31:476-480."},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1007\/BF02236924"},{"key":"ref32","unstructured":"Hemminki K, Li X, Dong C. Second primary cancers after sporadic and familial colorectal cancer. Cancer Epidemiol Biomarkers Prev 2001;10:793-798."},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1007\/BF02235755"},{"key":"ref34","unstructured":"Jass JR, Smyrk TC, Stewart SM, Lane MR, Lanspa SJ, Lynch HT. Pathology of hereditary non-polyposis colorectal cancer. Anticancer Res 1994;14:1631-1634."},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19980715)83:2&lt;240::AID-CNCR6&gt;3.0.CO;2-U"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8608876"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1093\/jjco\/hyh018"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1054\/bjoc.2000.1718"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19850201)55:3&lt;499::AID-CNCR2820550304&gt;3.0.CO;2-I"},{"key":"ref40","unstructured":"Yuan Y, Ye J, Zheng S. Clinical and genetic features of International Collaborative Group-hereditary nonpolyposis colorectal cancer families and suspected hereditary nonpolyposis colorectal cancer families. Chin Med J (Engl) 2004;117:748-752."},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.3816\/CCC.2003.n.015"},{"key":"ref42","unstructured":"Watson P, Lynch HT. The tumor spectrum in HNPCC. Anticancer Res 1994;14:1635-1639."},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1136\/gut.44.6.839"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.20874"},{"key":"ref45","unstructured":"Loukola A, Eklin K, Laiho P, Salovaara R, Kristo P, J&auml;rvinen H, Mecklin JP, Launonen V, Aaltonen LA. Microsatellite marker analysis in screening for hereditary nonpolyposis colorectal cancer (HNPCC). Cancer Res 2001;61:4545-4549."},{"key":"ref46","unstructured":"Aaltonen LA, Peltom&auml;ki P, Mecklin JP, J&auml;rvinen H, Jass JR, Green JS, Lynch HT, Watson P, Tallqvist G, Juhola M. Replication errors in benign and malignant tumors from hereditary nonpolyposis colorectal cancer patients. Cancer Res 1994;54:1645-1648."},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.3109\/00365529609094737"},{"key":"ref48","unstructured":"Boland CR, Thibodeau SN, Hamilton SR, Sidransky D, Eshleman JR, Burt RW, Meltzer SJ, Rodriguez-Bigas MA, Fodde R, Ranzani GN. A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer. Cancer Res 1998;58:5248-5257."},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/10.7.735"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1002\/1096-9896(2000)9999:9999&lt;::AID-PATH644&gt;3.0.CO;2-T"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1007\/s004280000325"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-8049(99)00208-7"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v113.pm9322509"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1086\/373963"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v11\/i11\/1673.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,18]],"date-time":"2019-08-18T13:37:21Z","timestamp":1566135441000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v11\/i11\/1673.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":54,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v11.i11.1673","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2005]]}}}