{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T13:41:39Z","timestamp":1775050899674,"version":"3.50.1"},"reference-count":72,"publisher":"Baishideng Publishing Group Inc.","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2005]]},"DOI":"10.3748\/wjg.v11.i3.309","type":"journal-article","created":{"date-parts":[[2014,10,22]],"date-time":"2014-10-22T13:17:40Z","timestamp":1413983860000},"page":"309","source":"Crossref","is-referenced-by-count":46,"title":["5-aminosalicylic acid is an attractive candidate agent for chemoprevention of colon cancer in patients with inflammatory bowel disease"],"prefix":"10.3748","volume":"11","author":[{"given":"Yang","family":"Cheng","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0953-6205(00)00061-3"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136\/gut.27.12.1408"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1007\/BF01393356"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.1999.01012.x"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-135"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(83)90129-0"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Yardley JH, Ransohoff DF, Riddell RH, Goldman H. Cancer in inflammatory bowel disease: how serious is the problem and what should be done about it? Gastroenterology 1983;85:197-200.","DOI":"10.1016\/S0016-5085(83)80252-2"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Ransohoff DF. Colon cancer in ulcerative colitis. Gastroenterology 1988;94:1089-1091.","DOI":"10.1016\/0016-5085(88)90573-2"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199011013231802"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1136\/gut.26.2.146"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/gut.29.1.49"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)91889-I"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1136\/gut.35.7.950"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Munkholm P, Langholz E, Davidsen M, Binder V. Intestinal cancer risk and mortality in patients with Crohn's disease. Gastroenterology 1993;105:1716-1723.","DOI":"10.1016\/0016-5085(93)91068-S"},{"key":"ref15","doi-asserted-by":"crossref","unstructured":"Persson PG, Karlén P, Bernell O, Leijonmarck CE, Broström O, Ahlbom A, Hellers G. Crohn's disease and cancer: a population-based cohort study. Gastroenterology 1994;107:1675-1679.","DOI":"10.1016\/0016-5085(94)90807-9"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1159\/000016851"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1136\/gut.42.5.711"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136\/gut.34.8.1075"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1136\/gut.46.4.500"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19930801)72:3+<984::AID-CNCR2820721306>3.0.CO;2-0"},{"key":"ref21","unstructured":"Ritland SR, Leighton JA, Hirsch RE, Morrow JD, Weaver AL, Gendler SJ. Evaluation of 5-aminosalicylic acid (5-ASA) for cancer chemoprevention: lack of efficacy against nascent adenomatous polyps in the Apc(Min) mouse. Clin Cancer Res 1999;5:855-863."},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1172\/JCI119651"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(98)70330-0"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(98)70526-8"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1993.115"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.312.7046.1563"},{"key":"ref27","doi-asserted-by":"crossref","unstructured":"Bjarnason I, Hayllar J, MacPherson AJ, Russell AS. Side effects of nonsteroidal anti-inflammatory drugs on the small and large intestine in humans. Gastroenterology 1993;104:1832-1847.","DOI":"10.1016\/0016-5085(93)90667-2"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1136\/gut.31.11.1271"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1007\/BF02660618"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(98)70627-4"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Pinczowski D, Ekbom A, Baron J, Yuen J, Adami HO. Risk factors for colorectal cancer in patients with ulcerative colitis: a case-control study. Gastroenterology 1994;107:117-120.","DOI":"10.1016\/0016-5085(94)90068-X"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.2000.00698.x"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-199612000-00009"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(99)70182-4"},{"key":"ref35","unstructured":"Yang F, Villiers WJS, McClain CJ, Varilek GW. Mesalazine modulates nuclear factor-κB\/IκB-alpha in Caco-2 cells. Gastroenterology 1997;112:A1125."},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1172\/JCI992"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.1999.00652.x"},{"key":"ref38","doi-asserted-by":"crossref","unstructured":"MacGregor DJ, Kim YS, Sleisenger MH, Johnson LK. Chemoprevention of colon cancer carcinogenesis by balsalazide: inhibition of azoxymethane-induced aberrant crypt formation in the rat colon and intestinal tumor formation in the B6-Min\/+ mouse. Int J Oncol 2000;17:173-179.","DOI":"10.3892\/ijo.17.1.173"},{"key":"ref39","unstructured":"Hixson LJ, Alberts DS, Krutzsch M, Einsphar J, Brendel K, Gross PH, Paranka NS, Baier M, Emerson S, Pamukcu R. Antiproliferative effect of nonsteroidal antiinflammatory drugs against human colon cancer cells. Cancer Epidemiol Biomarkers Prev 1994;3:433-438."},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8964397"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1023\/A:1005517112039"},{"key":"ref42","unstructured":"Schmutte C, Yang AS, Beart RW, Jones PA. Base excision repair of U: G mismatches at a mutational hotspot in the p53 gene is more efficient than base excision repair of T: G mismatches in extracts of human colon tumors. Cancer Res 1995;55:3742-3746."},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1136\/gut.42.3.351"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(94)92831-2"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026670027150"},{"key":"ref46","unstructured":"Tremaine WJ, Schroeder KW. Urinary sediment abnormalities in patients on long-term oral 5-aminosalicylic acid (5-ASA) for chronic ulcerative colitis (CUC). Gastroenterology 1988;94:A465."},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.296.6634.1442"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1159\/000064461"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200102000-00019"},{"key":"ref50","unstructured":"Nakajima H, Munakata A, Yoshida Y. Adverse effects of sulfasalazine and treatment of ulcerative colitis with mesalazine. J Gastroenterol 1995;30 Suppl 8:115-117."},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1248\/bpb.25.264"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-000-0006-z"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200007000-00014"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.02.071"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2036.18.s2.3.x"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1007\/s00384-002-0476-6"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/24.3.443"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1097\/00054725-200209000-00007"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.08718.x"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07599.x"},{"key":"ref61","unstructured":"Mouzas IA, Papavassiliou E, Koutroubakis I. Chemoprevention of colorectal cancer in inflammatory bowel disease? A potential role for folate. Ital J Gastroenterol Hepatol 1998;30:421-425."},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2002.tb01252.x"},{"key":"ref63","unstructured":"Bansal P, Sonnenberg A. Risk factors of colorectal cancer in inflammatory bowel disease. Am J Gastroenterol 1996;91:44-48."},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.2165\/00063030-200115050-00005"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(02)00047-X"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1007\/s002280000163"},{"key":"ref67","unstructured":"Van Assche G, Baert F, De Reuck M, De Vos M, De Wit O, Hoang P, Louis E, Mana F, Pelckmans P, Rutgeerts P. The role of aminosalicylates in the treatment of ulcerative colitis. Acta Gastroenterol Belg 2002;65:196-199."},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200305001-00014"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(01)00014-0"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1016\/S1052-5157(03)00063-1"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.suppl_5.v10"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1136\/gut.52.5.769"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v11\/i3\/309.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,26]],"date-time":"2020-08-26T01:55:25Z","timestamp":1598406925000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v11\/i3\/309.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":72,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v11.i3.309","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2005]]}}}