{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T18:37:34Z","timestamp":1775327854220,"version":"3.50.1"},"reference-count":31,"publisher":"Baishideng Publishing Group Inc.","issue":"42","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2005]]},"DOI":"10.3748\/wjg.v11.i42.6716","type":"journal-article","created":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T13:25:03Z","timestamp":1445001903000},"page":"6716","source":"Crossref","is-referenced-by-count":28,"title":["Relation of overexpression of S phase kinase-associated protein 2 with reduced expression of p27 and PTEN in human gastric carcinoma"],"prefix":"10.3748","volume":"11","author":[{"given":"Xiu-Mei","family":"Ma","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1126\/science.274.5293.1672"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1006\/excr.2000.5143"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4652(200004)183:1&lt;10::AID-JCP2&gt;3.0.CO;2-I"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1038\/24179"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(00)81237-4"},{"key":"ref6","unstructured":"Tan P, Cady B, Wanner M, Worland P, Cukor B, Magi-Galluzzi C, Lavin P, Draetta G, Pagano M, Loda M. The cell cycle inhibitor p27 is an independent prognostic marker in small (T1a,b) invasive breast carcinomas. Cancer Res 1997;57:1259-1263."},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1038\/nm0297-227"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1038\/nm0297-231"},{"key":"ref9","unstructured":"Esposito V, Baldi A, De Luca A, Groger AM, Loda M, Giordano GG, Caputi M, Baldi F, Pagano M, Giordano A. Prognostic role of the cyclin-dependent kinase inhibitor p27 in non-small cell lung cancer. Cancer Res 1997;57:3381-3385."},{"key":"ref10","unstructured":"Tsihlias J, Kapusta LR, DeBoer G, Morava-Protzner I, Zbieranowski I, Bhattacharya N, Catzavelos GC, Klotz LH, Slingerland JM. Loss of cyclin-dependent kinase inhibitor p27Kip1 is a novel prognostic factor in localized human prostate adenocarcinoma. Cancer Res 1998;58:542-548."},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19990415)85:8&lt;1711::AID-CNCR10&gt;3.0.CO;2-L"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1126\/science.7624798"},{"key":"ref13","unstructured":"Eguchi H, Herschenhous N, Kuzushita N, Moss SF. Helicobacter pylori increases proteasome-mediated degradation of p27(kip1) in gastric epithelial cells. Cancer Res 2003;63:4739-4746."},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1038\/12013"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(99)80290-5"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/19.9.2069"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.041475098"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.081474898"},{"key":"ref19","unstructured":"Kudo Y, Kitajima S, Sato S, Miyauchi M, Ogawa I, Takata T. High expression of S-phase kinase-interacting protein 2, human F-box protein, correlates with poor prognosis in oral squamous cell carcinomas. Cancer Res 2001;61:7044-7047."},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010501)91:9&lt;1745::AID-CNCR1193&gt;3.0.CO;2-H"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(01)00065-3"},{"key":"ref22","unstructured":"Yang G, Ayala G, De Marzo A, Tian W, Frolov A, Wheeler TM, Thompson TC, Harper JW. Elevated Skp2 protein expression in human prostate cancer: association with loss of the cyclin-dependent kinase inhibitor p27 and PTEN and with reduced recurrence-free survival. Clin Cancer Res 2002;8:3419-3426."},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1172\/JCI0215795"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.153.7.1381"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1126\/science.287.5461.2204"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)80020-2"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)80021-4"},{"key":"ref28","unstructured":"Konturek PC, Kania J, Konturek JW, Nikiforuk A, Konturek SJ, Hahn EG. H. pylori infection, atrophic gastritis, cytokines, gastrin, COX-2, PPAR gamma and impaired apoptosis in gastric carcinogenesis. Med Sci Monit 2003;9:SR53-SR66."},{"key":"ref29","unstructured":"Gottschalk AR, Basila D, Wong M, Dean NM, Brandts CH, Stokoe D, Haas-Kogan DA. p27Kip1 is required for PTEN-induced G1 growth arrest. Cancer Res 2001;61:2105-2111."},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"Yang L, Kuang LG, Zheng HC, Li JY, Wu DY, Zhang SM, Xin Y. PTEN encoding product: a marker for tumorigenesis and progression of gastric carcinoma. World J Gastroenterol 2003;9:35-39.","DOI":"10.3748\/wjg.v9.i1.35"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3835(00)00359-1"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v11\/i42\/6716.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,31]],"date-time":"2019-08-31T16:48:32Z","timestamp":1567270112000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v11\/i42\/6716.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005]]},"references-count":31,"journal-issue":{"issue":"42","published-print":{"date-parts":[[2005]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v11.i42.6716","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2005]]}}}