{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T12:43:37Z","timestamp":1784033017234,"version":"3.55.0"},"reference-count":61,"publisher":"Baishideng Publishing Group Inc.","issue":"17","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2006]]},"DOI":"10.3748\/wjg.v12.i17.2681","type":"journal-article","created":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T07:10:32Z","timestamp":1458112232000},"page":"2681","source":"Crossref","is-referenced-by-count":21,"title":["Central serotonergic and noradrenergic receptors in functional dyspepsia"],"prefix":"10.3748","volume":"12","author":[{"given":"S","family":"O\u2019Mahony","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.45.2008.ii37"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1136\/pmj.79.927.25"},{"key":"ref3","doi-asserted-by":"crossref","unstructured":"Soo S, Moayyedi P, Deeks J, Delaney B, Lewis M, Forman D. Psychological interventions for non-ulcer dyspepsia. Cochrane Database Syst Rev 2005;CD002301.","DOI":"10.1002\/14651858.CD002301.pub4"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.4065\/71.6.614"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.suppl_1.i63"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.08724.x"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(99)70179-4"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Baker DE. Rationale for using serotonergic agents to treat irritable bowel syndrome. Am J Health Syst Pharm 2005;62:700-711; quiz 712-3.","DOI":"10.1093\/ajhp\/62.7.700"},{"key":"ref9","unstructured":"Gershon MD. Serotonin and its implication for the management of irritable bowel syndrome. Rev Gastroenterol Disord 2003;3 Suppl 2:S25-S34."},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1097\/00004836-200207001-00005"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.4065\/75.9.907"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Talley NJ, Weaver AL, Zinsmeister AR. Impact of functional dyspepsia on quality of life. Dig Dis Sci 1995;40:584-589.","DOI":"10.1007\/BF02064375"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2004.04.006"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Alpers DH. Why should psychotherapy be a useful approach to management of patients with nonulcer dyspepsia. Gastroenterology 2000;119:869-871.","DOI":"10.1053\/gast.2000.17840"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.3109\/00365529509093244"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1001\/archinte.158.21.2357"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1007\/BF01296514"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1136\/gut.43.2.256"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-108-6-865"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(97)70056-8"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Mayer EA, Gebhart GF. Basic and clinical aspects of visceral hyperalgesia. Gastroenterology 1994;107:271-293.","DOI":"10.1016\/0016-5085(94)90086-8"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Al-Chaer ED, Lawand NB, Westlund KN, Willis WD. Visceral nociceptive input into the ventral posterolateral nucleus of the thalamus: a new function for the dorsal column pathway. J Neurophysiol 1996;76:2661-2674.","DOI":"10.1152\/jn.1996.76.4.2661"},{"key":"ref23","doi-asserted-by":"crossref","unstructured":"Al-Chaer ED, Feng Y, Willis WD. A role for the dorsal column in nociceptive visceral input into the thalamus of primates. J Neurophysiol 1998;79:3143-3150.","DOI":"10.1152\/jn.1998.79.6.3143"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1136\/gut.48.1.125"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Kim DY, Camilleri M. Serotonin: a mediator of the brain-gut connection. Am J Gastroenterol 2000;95:2698-2709.","DOI":"10.1111\/j.1572-0241.2000.03177.x"},{"key":"ref26","unstructured":"Nolte J. The Human Brain. 4<sup>th<\/sup> ed. Arizona. Mosby 1999;272-275."},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.ne.07.030184.001521"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/0166-4328(96)00072-1"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(93)90427-J"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(86)90470-X"},{"key":"ref31","doi-asserted-by":"crossref","unstructured":"Feuerstein HL, Herrting G. Serotonin (5-HT) enhances hippocampal noradrenaline (NA) release: evidence for facilitatory 5-HT receptors within the CNS. Naunyn- Schmeideberg&rsquo;s Arch Pharmacology 1986;333:191-197.","DOI":"10.1007\/BF00512929"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(84)90152-5"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.1992.tb00257.x"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Bharucha AE, Novak V, Camilleri M, Zinsmeister AR, Hanson RB, Low PA. Alpha 2-adrenergic modulation of colonic tone during hyperventilation. Am J Physiol 1997;273:G1135-G1140.","DOI":"10.1152\/ajpgi.1997.273.5.G1135"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1254\/jjp.62.329"},{"key":"ref36","doi-asserted-by":"crossref","unstructured":"Jiang Q, Sheldon RJ, Porreca F. Sites of clonidine action to inhibit gut propulsion in mice: demonstration of a central component. Gastroenterology 1988;95:1265-1271.","DOI":"10.1016\/0016-5085(88)90360-5"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.suppl_1.i77"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1136\/gut.44.1.55"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1007\/BF01307517"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1136\/gut.47.6.861"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.suppl_1.i25"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(95)90439-5"},{"key":"ref43","doi-asserted-by":"crossref","unstructured":"Delvaux MM. Stress and visceral perception. Can J Gastroenterol 1999;13 Suppl A:32A-36A.","DOI":"10.1155\/1999\/235916"},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/S0304-3959(98)00212-7"},{"key":"ref45","doi-asserted-by":"crossref","unstructured":"Greydanus MP, Vassallo M, Camilleri M, Nelson DK, Hanson RB, Thomforde GM. Neurohormonal factors in functional dyspepsia: insights on pathophysiological mechanisms. Gastroenterology 1991;100:1311-1318.","DOI":"10.1016\/0016-5085(91)70018-S"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1136\/gut.35.3.327"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(94)90536-3"},{"key":"ref48","doi-asserted-by":"crossref","unstructured":"Tougas G. The autonomic nervous system in functional bowel disorders. Gut 2000;47 Suppl 4:iv78-iv80; discussion iv87.","DOI":"10.1136\/gut.47.suppl_4.iv78"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1016\/0306-4522(96)00292-8"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1001\/archpsyc.1997.01830150070011"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1007\/s11938-005-0026-8"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1016\/S0889-8553(05)70363-0"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(94)90026-4"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2000.16493"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.3109\/00365529009095527"},{"key":"ref56","unstructured":"Neuhauser H, Laakmann G, Knossalla A. Neuroendocrine effects of buspirone. 16<sup>th<\/sup> CINP congress. Psychopharmacology 1988;96 Suppl 1:393."},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-005-0018-9"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1016\/0022-3999(90)90032-Y"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1210\/jcem-44-5-1010"},{"key":"ref60","unstructured":"Salvatore R. The standards of human growth hormone assays. In Evaluation of Growth Hormone Secretion (Edited by Laron and Butenandt). Bascl: Karger 1983;."},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1192\/bjp.156.5.680"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","deposited":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T05:43:22Z","timestamp":1655271802000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v12\/i17\/2681.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":61,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2006]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v12.i17.2681","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2006]]}}}