{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,19]],"date-time":"2026-02-19T02:31:47Z","timestamp":1771468307164,"version":"3.50.1"},"reference-count":156,"publisher":"Baishideng Publishing Group Inc.","issue":"45","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2006]]},"DOI":"10.3748\/wjg.v12.i45.7250","type":"journal-article","created":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T07:53:29Z","timestamp":1458114809000},"page":"7250","source":"Crossref","is-referenced-by-count":17,"title":["Concept on the pathogenesis and treatment of primary biliary cirrhosis"],"prefix":"10.3748","volume":"12","author":[{"given":"Vasiliy Ivanovich","family":"Reshetnyak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","unstructured":"Loginov \u0410\u0421. Classification and nomenclature of chronic liver diseases. Rossiyskiy Gastroenterologicheskiy Zhurnal 1995;2:3-8."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"Charatcharoenwitthaya P, Lindor KD. Current concepts in the pathogenesis of primary biliary cirrhosis. Ann Hepatol 2005;4:161-175.","DOI":"10.1016\/S1665-2681(19)32061-7"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-916324"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1136\/gut.50.6.743"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.41157.x"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20491"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Inoue T, Shiraki K, Fuke H, Yamanaka Y, Miyashita K, Ito K, Suzuki M, Sugimoto K, Murata K, Nakano T. Primary biliary cirrhosis after aortoiliac reconstruction surgery using a Y-graft. World J Gastroenterol 2005;11:6219-6220.","DOI":"10.3748\/wjg.v11.i39.6219"},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Amano K, Leung PS, Rieger R, Quan C, Wang X, Marik J, Suen YF, Kurth MJ, Nantz MH, Ansari AA. Chemical xenobiotics and mitochondrial autoantigens in primary biliary cirrhosis: identification of antibodies against a common environmental, cosmetic, and food additive, 2-octynoic acid. J Immunol 2005;174:5874-5883.","DOI":"10.4049\/jimmunol.174.9.5874"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(03)00101-6"},{"key":"ref10","unstructured":"Golovnova EV, Il'chenko LIu, Tsaregorodtseva TM, Serova TI, Gudkova RV, Shepeleva SD, Tkachev VD. [Primary biliary cirrhosis: 12-year experience in observation]. Ter Arkh 2003;75:26-30."},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2003.023937"},{"key":"ref12","unstructured":"Tanaka A, Miyakawa H, Luketic VA, Kaplan M, Storch WB, Gershwin ME. The diagnostic value of anti-mitochondrial antibodies, especially in primary biliary cirrhosis. Cell Mol Biol (Noisy-le-grand) 2002;48:295-299."},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.2188\/jea.16.30"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.2177\/jsci.28.117"},{"key":"ref15","unstructured":"Zhang FK, Jia JD, Wang BE. Clinical evaluation of serum antimitochondrial antibody-negative primary biliary cirrhosis. Hepatobiliary Pancreat Dis Int 2004;3:288-291."},{"key":"ref16","unstructured":"Miyachi K, Shibata M, Hasegawa C, Onozuka Y, Fritzler MJ. [Case of primary biliary cirrhosis patient with anti-p97\/VCP antibodies presenting a mild clinical course]. Rinsho Byori 2005;53:19-23."},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.11.005"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1080\/10446670410001722113"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1034\/j.1478-3231.2003.00857.x"},{"key":"ref20","unstructured":"Wenchich L, Krechler T, Horak J, Sedivá A, Bart\u016fnková J, Hansiková H, Martásek P, Zeman J, Svestka T. [Primary biliary cirrhosis--specific anti-mitochondrial antibodies]. Vnitr Lek 2004;50:842-845."},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20859"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Amano K, Leung PS, Xu Q, Marik J, Quan C, Kurth MJ, Nantz MH, Ansari AA, Lam KS, Zeniya M. Xenobiotic-induced loss of tolerance in rabbits to the mitochondrial autoantigen of primary biliary cirrhosis is reversible. J Immunol 2004;172:6444-6452.","DOI":"10.4049\/jimmunol.172.10.6444"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840100321"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1016\/S1568-9972(01)00020-9"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1080\/07853890310018467"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(03)00501-4"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1080\/00365520410003236"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1097\/01.bor.0000130538.76808.c2"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(89)92034-5"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(05)80225-9"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(94)80255-6"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2362.1997.1690724.x"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2004.03.002"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20788"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50446"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.40397.x"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.41121.x"},{"key":"ref38","unstructured":"MacSween RNM, Anthoni PP, Schener JJ. Pathology of the liver. Edinbourgh Pub 1979;458."},{"key":"ref39","unstructured":"Loginov AS. Aruin LI Clinical morphology of the liver Moscow: Meditsina Publishers; 1985;181."},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.1080\/17402520400004177"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1827.2003.01426.x"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0676.2003.00807.x"},{"key":"ref43","unstructured":"Golovanova EV, Il'chenko LIu, Tsaregorodtseva TM, Serova TI, Gudkova RB. [Cytokines in primary biliary cirrhosis (diagnostic and prognostic value)]. Ter Arkh 2004;76:8-11."},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20705"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(03)00096-5"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2004.09.024"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.3700285"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1746.2002.02689.x"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1016\/S0925-4439(02)00225-9"},{"key":"ref50","doi-asserted-by":"crossref","unstructured":"Wu CT, Eiserich JP, Ansari AA, Coppel RL, Balasubramanian S, Bowlus CL, Gershwin ME, Van De Water J. Myeloperoxidase-positive inflammatory cells participate in bile duct damage in primary biliary cirrhosis through nitric oxide-mediated reactions. Hepatology 2003;38:1018-1025.","DOI":"10.1002\/hep.1840380428"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1002\/path.1729"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1053\/hupa.2002.128060"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.42.947"},{"key":"ref54","doi-asserted-by":"crossref","unstructured":"Yokomori H, Oda M, Ogi M, Wakabayashi G, Kawachi S, Yoshimura K, Nagai T, Kitajima M, Nomura M, Hibi T. Expression of adhesion molecules on mature cholangiocytes in canal of Hering and bile ductules in wedge biopsy samples of primary biliary cirrhosis. World J Gastroenterol 2005;11:4382-4389.","DOI":"10.3748\/wjg.v11.i28.4382"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(02)00010-7"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1433063100"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(03)00132-6"},{"key":"ref58","unstructured":"Gentilini P, Teodori U, Gorini S, Popper H. Intrahepatic cholestasis New-York: Raven-press Pub; 1975;."},{"key":"ref59","unstructured":"Lopukhin YuM, Archakov AI, Vladimirov YuA, Kogan EM. Cholesterinosis Moscow: Meditsina Publishers; 1983;."},{"key":"ref60","unstructured":"Loginov AS. Intrahepatic cholestasis: a cardinal problem of modern hepatology. Collected articles “Topical aspects of gastroenterology”. \u041c., 1977;3-12."},{"key":"ref61","unstructured":"Zhang F, Jia J, Wang B, Qian L, Yin S, Wang Y, Cui Y, You H, Ma H, Wang H. [Clinical characteristics of primary biliary cirrhosis: a report of 45 cases]. Zhonghua Neike Zazhi 2002;41:163-167."},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1007\/BF01320264"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1172\/JCI106260"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1016\/0009-8981(73)90313-6"},{"key":"ref65","unstructured":"Metzler DE. Biochemistry. In three volumes. Translated from English Moscow: Mir Publishers; 1980;119."},{"key":"ref66","unstructured":"Angelico M, Alvaro D, Attili AF, and Cantafora A. Mechanisms of secretion of biliary phosphatidylcholines: the role of bile acids. Ital J Gastroenterol 1985;17:278-281."},{"key":"ref67","unstructured":"Romanenko VD. The effect of alkaline phosphatase on the biligenic function of the liver and the bile electrolyte excretion. Fiziologichniy Zhurnal 1971;17:790-793."},{"key":"ref68","unstructured":"Reshetnyak VI, Ozerova IN, Perova NV, Ilchenko LIu, Tkachev VD, Golovanova EV, Vinnickaya EV. Investigation of the lipid composition of liver cells and serum in patients with primary biliary cirrhosis (PBC). Rossiyskiy Gastroenterologicheskiy Zhurnal 2001;2:143-144."},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2362.2003.01238.x"},{"key":"ref70","doi-asserted-by":"crossref","unstructured":"Yokomori H, Oda M, Wakabayashi G, Kitajima M, Yoshimura K, Nomura M, Hibi T. High expressions of caveolins on the proliferating bile ductules in primary biliary cirrhosis. World J Gastroenterol 2005;11:3710-3713.","DOI":"10.3748\/wjg.v11.i24.3710"},{"key":"ref71","doi-asserted-by":"crossref","unstructured":"Jorge AD, Gutierrez LS, Jorge O, Burgos MH. Ultrastructural and cytochemical changes in the liver of primary biliary cirrhosis patients. Biocell 2002;26:253-262.","DOI":"10.32604\/biocell.2002.26.253"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1007\/BF00840644"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.25086"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.33634"},{"key":"ref75","unstructured":"Nemchausky BA, Layden TJ, Boyer JL. Effects of chronic choleretic infusions of bile acids on the membrane of the bile canaliculus. A biochemical and morphologic study. Lab Invest 1977;36:259-267."},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(87)91610-2"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(02)00439-7"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1136\/gut.51.2.265"},{"key":"ref79","doi-asserted-by":"crossref","unstructured":"Kanda T, Yokosuka O, Kojima H, Imazeki F, Nagao K, Tatsuno I, Saito Y, Saisho H. Severe hypercholesterolemia associated with primary biliary cirrhosis in a 44-year-old Japanese woman. World J Gastroenterol 2004;10:2607-2608.","DOI":"10.3748\/wjg.v10.i17.2607"},{"key":"ref80","doi-asserted-by":"crossref","unstructured":"Stiehl A. Disturbances of bile acid metabolism in cholestasis. Clin Gastroenterol 1977;6:45-67.","DOI":"10.1016\/S0300-5089(21)00385-0"},{"key":"ref81","unstructured":"Markova MN. Cholestatic hperlipemia in patients with primary biliary cirrhosis. Collected Articles. \"Gastroenter-ology-78\". Vilnius 1978;150-152."},{"key":"ref82","unstructured":"Molostova LV. Hyperlipidemia in chronic intrahepatic cholestasis. Collected Articles. \"Chronic Hepatitis \". Moscow 1988;51-59."},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(03)00096-5"},{"key":"ref84","doi-asserted-by":"publisher","DOI":"10.1172\/JCI102223"},{"key":"ref85","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(03)00097-7"},{"key":"ref86","unstructured":"Zhang F, Jia J, Cui R, Wang B, Wang H. Clinical features of forty patients with primary biliary cirrhosis. Chin Med J (Engl) 2002;115:904-908."},{"key":"ref87","unstructured":"Sherlock S, Dooley J. Diseases of the liver and biliary system. 9th ed Oxford: Blackwell Sci Pub; 1993;44-58."},{"key":"ref88","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(03)00105-3"},{"key":"ref89","unstructured":"Loginov AS. Bile acid metabolism in liver disease with intrahepatic cholestasis In: Mechanisms of resistance impairment, adaptation, and compensation. Tashkent; 1976;51-52."},{"key":"ref90","unstructured":"Molostova LV. Secretion and metabolism of bile acids in different forms of their impaired hepatoenteric circulation and in chronic liver diseases (Experimental and clinical studies). Dissertation for the academic degree of doctor of biological sciences. Moscow 1982;284p."},{"key":"ref91","doi-asserted-by":"publisher","DOI":"10.1038\/213093b0"},{"key":"ref92","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1974.tb00373.x"},{"key":"ref93","doi-asserted-by":"publisher","DOI":"10.1159\/000199278"},{"key":"ref94","doi-asserted-by":"crossref","unstructured":"Greim H, Trülzsch D, Czygan P, Rudick J, Hutterer F, Schaffner F, Popper H. Mechanism of cholestasis. 6. Bile acids in human livers with or without biliary obstruction. Gastroenterology 1972;63:846-850.","DOI":"10.1016\/S0016-5085(19)33226-3"},{"key":"ref95","doi-asserted-by":"crossref","unstructured":"Greim H, Trülzsch D, Roboz J, Dressler K, Czygan P, Hutterer F, Schaffner F, Popper H. Mechanism of cholestasis. 5. Bile acids in normal rat livers and in those after bile duct ligation. Gastroenterology 1972;63:837-845.","DOI":"10.1016\/S0016-5085(19)33225-1"},{"key":"ref96","unstructured":"Alme B, Bremmelgaard A, Sjovall J, Thomassen G. Complexity of the bile acid mixture in human urine In: Advances in bile acid research. Matern S, Hackenschmidt J, Back P, Gerok W. Stuttgart, editors. New York; 1974;145-148."},{"key":"ref97","doi-asserted-by":"crossref","unstructured":"Lino M, Binaut R, Noël LH, Patey N, Rustin P, Daniel L, Serpaggi J, Varaut A, Vanhille P, Knebelmann B. Tubulointerstitial nephritis and Fanconi syndrome in primary biliary cirrhosis. Am J Kidney Dis 2005;46:e41-e46.","DOI":"10.1053\/j.ajkd.2005.05.021"},{"key":"ref98","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(02)00046-5"},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2004.08.022"},{"key":"ref100","doi-asserted-by":"crossref","unstructured":"Loginov AS, Reshetniak VI, Astaf'eva OV, Gavrilova AIu. [The level of steroid hormones in patients with primary biliary liver cirrhosis]. Biull Eksp Biol Med 1990;109:237-239.","DOI":"10.1007\/BF00839641"},{"key":"ref101","doi-asserted-by":"publisher","DOI":"10.1172\/JCI109620"},{"key":"ref102","unstructured":"Moseley RH. Mechanisms of bile formation and cholestasis: clinical significance of recent experimental work. Am J Gastroenterol 1986;81:731-735."},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2001.04134.x"},{"key":"ref104","unstructured":"Di Bisceglie AM, Loyet M, Peters M. Long term follow up of bone mineral density in patients with primary biliary cirrhosis. Minerva Med 2004;95:529-534."},{"key":"ref105","unstructured":"Loginov AS, Salman MM, Sivash ES, Yarceva AM, Stavinskaya AA. Changes in the lung, gastrointestinal tract, and bones in patients with primary biliary cirrhosis (according to the data of X-ray studies) In: Topical aspects of gastroenterology. Moscow; 1977;40-44."},{"key":"ref106","unstructured":"Loginov AS, Stavinskaya AA, Sivash ES. Changes in the skeletal system in primary biliary cirrhosis. Vestnik Rentgenologii I Radiologii 1984;6:20-22."},{"key":"ref107","unstructured":"Stavinskaya AA. Capacities of X-ray study in primary biliary cirrhosis. Dissertation for the academic degree of candidate of medical sciences. Moscow 1985;."},{"key":"ref108","unstructured":"Gua\u00f1abens N, Parés A, Mari\u00f1oso L, Brancós MA, Piera C, Serrano S, Rivera F, Rodés J. Factors influencing the development of metabolic bone disease in primary biliary cirrhosis. Am J Gastroenterol 1990;85:1356-1362."},{"key":"ref109","doi-asserted-by":"publisher","DOI":"10.1111\/j.1400-1746.2004.03517.x"},{"key":"ref110","doi-asserted-by":"publisher","DOI":"10.1007\/s001980200092"},{"key":"ref111","unstructured":"Lakatos PL, Bajnok E, Tornai I, Folhoffer A, Horváth A, Lakatos P, Szalay F. [Decreased bone mineral density and gene polymorphism in primary biliary cirrhosis]. Orv Hetil 2004;145:331-336."},{"key":"ref112","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.01890.x"},{"key":"ref113","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200509000-00007"},{"key":"ref114","unstructured":"García-Suárez C, Crespo J, Fernández-Gil PL, Amado JA, García-Unzueta MT, Pons Romero F. [Plasma leptin levels in patients with primary biliary cirrhosis and their relationship with degree of fibrosis]. Gastroenterol Hepatol 2004;27:47-50."},{"key":"ref115","doi-asserted-by":"publisher","DOI":"10.1007\/BF01623380"},{"key":"ref116","doi-asserted-by":"publisher","DOI":"10.1378\/chest.102.5.1426"},{"key":"ref117","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(03)00410-0"},{"key":"ref118","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.10252"},{"key":"ref119","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.11.009"},{"key":"ref120","unstructured":"Tromm A, May B, Klein CG, Klein R, Fisseler-Eckhoff A, Griga T. Long-term response of primary biliary cirrhosis (stage I) to therapy with ursodeoxycholic acid. Hepatogastroenterology 2005;52:753-756."},{"key":"ref121","doi-asserted-by":"crossref","unstructured":"Dohmen K, Mizuta T, Nakamuta M, Shimohashi N, Ishibashi H, Yamamoto K. Fenofibrate for patients with asymptomatic primary biliary cirrhosis. World J Gastroenterol 2004;10:894-898.","DOI":"10.3748\/wjg.v10.i6.894"},{"key":"ref122","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(03)00192-2"},{"key":"ref123","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-200212000-00014"},{"key":"ref124","doi-asserted-by":"publisher","DOI":"10.1016\/S1590-8658(02)80112-8"},{"key":"ref125","unstructured":"Van Den Bogaert E, Francque S, Pelckmans P, Michielsen P. The use of ursodeoxycholic acid in patients with primary biliary cirrhosis: sense or nonsense. Acta Gastroenterol Belg 2003;66:283-287."},{"key":"ref126","doi-asserted-by":"publisher","DOI":"10.1046\/j.0106-9543.2002.01640.x"},{"key":"ref127","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2005.02307.x"},{"key":"ref128","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20646"},{"key":"ref129","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20568"},{"key":"ref130","doi-asserted-by":"crossref","unstructured":"Gluud C, Christensen E. Ursodeoxycholic acid for primary biliary cirrhosis. Cochrane Database Syst Rev 2002;CD000551.","DOI":"10.1002\/14651858.CD000551"},{"key":"ref131","unstructured":"Ursodeoxycholic acid: a second look. Primary biliary cirrhosis: dashed hopes. Prescrire Int 2002;11:67-69."},{"key":"ref132","unstructured":"Avezov SA, Mansurov FKh. [Efficacy of combined administration of ursodeoxycholic acid and hepthral in the treatment of primary biliary cirrhosis]. Klin Med (Mosk) 2004;82:55-58."},{"key":"ref133","doi-asserted-by":"publisher","DOI":"10.1136\/gut.50.3.436"},{"key":"ref134","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.08662.x"},{"key":"ref135","doi-asserted-by":"publisher","DOI":"10.1016\/S1542-3565(03)00134-4"},{"key":"ref136","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.30204.x"},{"key":"ref137","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-4-13"},{"key":"ref138","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2796.2002.01066.x"},{"key":"ref139","doi-asserted-by":"crossref","unstructured":"Gua\u00f1abens N, Parés A, Ros I, Alvarez L, Pons F, Caballería L, Monegal A, Martínez de Osaba MJ, Roca M, Peris P. Alendronate is more effective than etidronate for increasing bone mass in osteopenic patients with primary biliary cirrhosis. Am J Gastroenterol 2003;98:2268-2274.","DOI":"10.1016\/S0002-9270(03)00550-1"},{"key":"ref140","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2005.01026.x"},{"key":"ref141","doi-asserted-by":"crossref","unstructured":"Prince M, Christensen E, Gluud C. Glucocorticosteroids for primary biliary cirrhosis. Cochrane Database Syst Rev 2005;CD003778.","DOI":"10.1002\/14651858.CD003778.pub2"},{"key":"ref142","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07182.x"},{"key":"ref143","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2003.07173.x"},{"key":"ref144","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000177230.13770.4e"},{"key":"ref145","doi-asserted-by":"publisher","DOI":"10.1046\/j.1526-0968.2003.00085.x"},{"key":"ref146","unstructured":"Cukovi\u0107-Cavka S. [Primary biliary cirrhosis]. Acta Med Croatica 2003;57:221-225."},{"key":"ref147","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(03)00100-4"},{"key":"ref148","unstructured":"Gunson BK, Buckels JA, Elias E, McMaster P, Neuberger JM. Liver transplantation for primary biliary cirrhosis: the effect of disease stage at referral upon outcome after liver replacement. Transplant Proc 1990;22:1503-1504."},{"key":"ref149","doi-asserted-by":"publisher","DOI":"10.1136\/gut.31.9.1069"},{"key":"ref150","unstructured":"Sherlock S, Dooley J. Diseases of the liver and biliary system. 9th ed Oxford: Blackwell Sci Pub; 1993;236-248."},{"key":"ref151","unstructured":"Dietze O, Vogel W, Margreiter R. Primary biliary cirrhosis (PBC) after liver transplantation. Transplant Proc 1990;22:1501-1502."},{"key":"ref152","doi-asserted-by":"crossref","unstructured":"Polson RJ, Portmann B, Neuberger J, Calne RY, Williams R. Evidence for disease recurrence after liver transplantation for primary biliary cirrhosis. Clinical and histologic follow-up studies. Gastroenterology 1989;97:715-725.","DOI":"10.1016\/0016-5085(89)90643-4"},{"key":"ref153","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840080439"},{"key":"ref154","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(03)00093-X"},{"key":"ref155","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(03)00103-X"},{"key":"ref156","doi-asserted-by":"publisher","DOI":"10.1016\/S1089-3261(03)00098-9"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v12\/i45\/7250.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,15]],"date-time":"2022-06-15T05:52:37Z","timestamp":1655272357000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v12\/i45\/7250.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":156,"journal-issue":{"issue":"45","published-print":{"date-parts":[[2006]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v12.i45.7250","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2006]]}}}