{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,5]],"date-time":"2025-10-05T19:52:11Z","timestamp":1759693931114},"reference-count":10,"publisher":"Baishideng Publishing Group Inc.","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2006]]},"DOI":"10.3748\/wjg.v12.i5.809","type":"journal-article","created":{"date-parts":[[2016,3,16]],"date-time":"2016-03-16T04:35:06Z","timestamp":1458102906000},"page":"809","source":"Crossref","is-referenced-by-count":8,"title":["First report of a<i>de novo<\/i>germline mutation in the<i>MLH1<\/i>gene"],"prefix":"10.3748","volume":"12","author":[{"given":"Rein P","family":"Stulp","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","unstructured":"Vasen HF, Mecklin JP, Khan PM, Lynch HT. The International Collaborative Group on HNPCC. Anticancer Res 1994;14:1661-1664."},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(99)70510-X"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(85)90390-0"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djh034"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1086\/337944"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Wu Y, Nystr&ouml;m-Lahti M, Osinga J, Looman MW, Peltom&auml;ki P, Aaltonen LA, de la Chapelle A, Hofstra RM, Buys CH. MSH2 and MLH1 mutations in sporadic replication error-positive colorectal carcinoma as assessed by two-dimensional DNA electrophoresis. Genes Chromosomes Cancer 1997;18:269-278.","DOI":"10.1002\/(SICI)1098-2264(199704)18:4<269::AID-GCC4>3.0.CO;2-Z"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1086\/302612"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1002\/humu.10212"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Peltom&auml;ki P, Vasen H. Mutations associated with HNPCC predisposition -- Update of ICG-HNPCC\/INSiGHT mutation database. Dis Markers 2004;20:269-276.","DOI":"10.1155\/2004\/305058"},{"key":"ref10","unstructured":"Kraus C, Kastl S, G&uuml;nther K, Klessinger S, Hohenberger W, Ballhausen WG. A proven de novo germline mutation in HNPCC. J Med Genet 1999;36:919-921."}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v12\/i5\/809.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,5]],"date-time":"2019-09-05T11:51:34Z","timestamp":1567684294000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v12\/i5\/809.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2006]]},"references-count":10,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2006]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v12.i5.809","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2006]]}}}