{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T19:02:22Z","timestamp":1761418942552},"reference-count":127,"publisher":"Baishideng Publishing Group Inc.","issue":"30","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2014]]},"DOI":"10.3748\/wjg.v20.i30.10405","type":"journal-article","created":{"date-parts":[[2014,8,18]],"date-time":"2014-08-18T05:46:20Z","timestamp":1408340780000},"page":"10405","source":"Crossref","is-referenced-by-count":17,"title":["Pancreatic cancer-improved care achievable"],"prefix":"10.3748","volume":"20","author":[{"given":"Trond A","family":"Buanes","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.3322\/caac.20138"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdt301"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01510.x"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.epi-07-0341"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i15.2368"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp020"},{"key":"ref7","doi-asserted-by":"crossref","unstructured":"Everhart J, Wright D. Diabetes mellitus as a risk factor for pancreatic cancer. A meta-analysis. JAMA 1995;273:1605-1609.","DOI":"10.1001\/jama.1995.03520440059037"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i30.4861"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.08.044"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i26.4234"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mds140"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01597.x"},{"key":"ref13","doi-asserted-by":"crossref","unstructured":"Lowenfels AB, Maisonneuve P, DiMagno EP, Elitsur Y, Gates LK, Perrault J, Whitcomb DC. Hereditary pancreatitis and the risk of pancreatic cancer. International Hereditary Pancreatitis Study Group. J Natl Cancer Inst 1997;89:442-446.","DOI":"10.1093\/jnci\/89.6.442"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Howes N, Lerch MM, Greenhalf W, Stocken DD, Ellis I, Simon P, Truninger K, Ammann R, Cavallini G, Charnley RM. Clinical and genetic characteristics of hereditary pancreatitis in Europe. Clin Gastroenterol Hepatol 2004;2:252-261.","DOI":"10.1016\/S1542-3565(04)00013-8"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/ng1096-141"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1038\/nm1087"},{"key":"ref17","unstructured":"Hruban RH, Maitra A, Goggins M. Update on pancreatic intraepithelial neoplasia. Int J Clin Exp Pathol 2008;1:306-316."},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-006-1166-5"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0901557"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.pathmechdis.3.121806.154305"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.25449"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1126\/science.1164368"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1038\/nature09515"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1159\/000210262"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31825ffbfb"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1038\/nature09460"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.ccr-08-1966"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2011.12.029"},{"key":"ref29","doi-asserted-by":"crossref","unstructured":"Tatsuta M, Iishi H, Ichii M, Noguchi S, Yamamoto R, Yamamura H, Okuda S. Values of carcinoembryonic antigen, elastase 1, and carbohydrate antigen determinant in aspirated pancreatic cystic fluid in the diagnosis of cysts of the pancreas. Cancer 1986;57:1836-1839.","DOI":"10.1002\/1097-0142(19860501)57:9<1836::AID-CNCR2820570922>3.0.CO;2-D"},{"key":"ref30","doi-asserted-by":"crossref","unstructured":"van der Waaij LA, van Dullemen HM, Porte RJ. Cyst fluid analysis in the differential diagnosis of pancreatic cystic lesions: a pooled analysis. Gastrointest Endosc 2005;62:383-389.","DOI":"10.1016\/S0016-5107(05)01581-6"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2012.04.004"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.25070"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000216763.27673.97"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2011.12.016"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.11.004"},{"key":"ref36","doi-asserted-by":"crossref","unstructured":"Tempero MA, Arnoletti JP, Behrman SW, Ben-Josef E, Benson AB, Casper ES, Cohen SJ, Czito B, Ellenhorn JD, Hawkins WG. Pancreatic Adenocarcinoma, version 2.2012: featured updates to the NCCN Guidelines. J Natl Compr Canc Netw 2012;10:703-713.","DOI":"10.6004\/jnccn.2012.0073"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-009-0408-6"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.8992"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.6407"},{"key":"ref40","unstructured":"Torreggiani WC, Lyburn I, Harris AA, Zwirewich CV. Seeding of pancreatic cancer along the path of a surgical drain: case report and literature review. Can Assoc Radiol J 2000;51:241-243."},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000046"},{"key":"ref42","unstructured":"Argani P, Rosty C, Reiter RE, Wilentz RE, Murugesan SR, Leach SD, Ryu B, Skinner HG, Goggins M, Jaffee EM. Discovery of new markers of cancer through serial analysis of gene expression: prostate stem cell antigen is overexpressed in pancreatic adenocarcinoma. Cancer Res 2001;61:4320-4324."},{"key":"ref43","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.0050123"},{"key":"ref44","doi-asserted-by":"crossref","unstructured":"Foss CA, Fox JJ, Feldmann G, Maitra A, Iacobuzio-Donohue C, Kern SE, Hruban R, Pomper MG. Radiolabeled anti-claudin 4 and anti-prostate stem cell antigen: initial imaging in experimental models of pancreatic cancer. Mol Imaging 2007;6:131-139.","DOI":"10.2310\/7290.2007.00010"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1186\/1756-9966-32-71"},{"key":"ref46","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2000.01699.x"},{"key":"ref47","doi-asserted-by":"publisher","DOI":"10.1016\/s1470-2045(08)70001-9"},{"key":"ref48","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-0985-4"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22852"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3180691579"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.22916"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2004.04.030"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01202.x"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31821fd334"},{"key":"ref55","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e3181ad657b"},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31823ac299"},{"key":"ref57","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-011-1263-8"},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdt239"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-9929-7"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1200\/jop.2010.000040"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1200\/jop.2010.000041"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1007\/s11864-013-0244-6"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2007.12.020"},{"key":"ref64","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-010-1285-8"},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2007.15.8634"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pmed.1000267"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e31811eaa2c"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000259391.84304.2b"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-9839-8"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1007\/s00423-009-0494-8"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.5397"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2013.781218"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2009.10.019"},{"key":"ref74","doi-asserted-by":"crossref","unstructured":"Tempero MA, Arnoletti JP, Behrman S, Ben-Josef E, Benson AB, Berlin JD, Cameron JL, Casper ES, Cohen SJ, Duff M. Pancreatic adenocarcinoma. J Natl Compr Canc Netw 2010;8:972-1017.","DOI":"10.6004\/jnccn.2010.0073"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-984952"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2010.1275"},{"key":"ref77","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2011.38.2960"},{"key":"ref78","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-2882-0"},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-013-2886-9"},{"key":"ref80","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.09.067"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.11.027"},{"key":"ref82","doi-asserted-by":"crossref","unstructured":"Lillemoe KD, Cameron JL, Yeo CJ, Sohn TA, Nakeeb A, Sauter PK, Hruban RH, Abrams RA, Pitt HA. Pancreaticoduodenectomy. Does it have a role in the palliation of pancreatic cancer? Ann Surg 1996;223:718-725; discussion 725-728.","DOI":"10.1097\/00000658-199606000-00010"},{"key":"ref83","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318263da2f"},{"key":"ref84","doi-asserted-by":"publisher","DOI":"10.1016\/j.pan.2013.01.003"},{"key":"ref85","doi-asserted-by":"crossref","unstructured":"Burris HA, Moore MJ, Andersen J, Green MR, Rothenberg ML, Modiano MR, Cripps MC, Portenoy RK, Storniolo AM, Tarassoff P. Improvements in survival and clinical benefit with gemcitabine as first-line therapy for patients with advanced pancreas cancer: a randomized trial. J Clin Oncol 1997;15:2403-2413.","DOI":"10.1200\/JCO.1997.15.6.2403"},{"key":"ref86","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1011923"},{"key":"ref87","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23392"},{"key":"ref88","doi-asserted-by":"crossref","unstructured":"Neoptolemos JP, Dunn JA, Stocken DD, Almond J, Link K, Beger H, Bassi C, Falconi M, Pederzoli P, Dervenis C. Adjuvant chemoradiotherapy and chemotherapy in resectable pancreatic cancer: a randomised controlled trial. Lancet 2001;358:1576-1585.","DOI":"10.1016\/S0140-6736(01)06651-X"},{"key":"ref89","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa032295"},{"key":"ref90","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602513"},{"key":"ref91","doi-asserted-by":"crossref","unstructured":"Ghaneh P, Slavin J, Sutton R, Hartley M, Neoptolemos JP. Adjuvant therapy in pancreatic cancer. World J Gastroenterol 2001;7:482-489.","DOI":"10.3748\/wjg.v7.i4.482"},{"key":"ref92","doi-asserted-by":"publisher","DOI":"10.1001\/jama.297.3.267"},{"key":"ref93","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2007.13.9014"},{"key":"ref94","doi-asserted-by":"publisher","DOI":"10.1200\/jco.2008.16.9326"},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1038\/nature10673"},{"key":"ref96","doi-asserted-by":"crossref","unstructured":"Gjertsen MK, Bjorheim J, Saeterdal I, Myklebust J, Gaudernack G. Cytotoxic CD4+ and CD8+ T lymphocytes, generated by mutant p21-ras (12Val) peptide vaccination of a patient, recognize 12Val-dependent nested epitopes present within the vaccine peptide and kill autologous tumour cells carrying this mutation. Int J Cancer 1997;72:784-790.","DOI":"10.1002\/(SICI)1097-0215(19970904)72:5<784::AID-IJC14>3.0.CO;2-9"},{"key":"ref97","doi-asserted-by":"publisher","DOI":"10.1016\/j.currproblcancer.2013.10.004"},{"key":"ref98","unstructured":"Vasef MA, Ross JS, Cohen MB. Telomerase activity in human solid tumors. Diagnostic utility and clinical applications. Am J Clin Pathol 1999;112:S68-S75."},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6603437"},{"key":"ref100","doi-asserted-by":"crossref","unstructured":"Buanes T, Maurel J, Liauw W, Hebbar M, Nemunaitis J. A randomized Phase III study of gemcitabine (G) versus GV1001 in sequential combination with G in patients with unresectable and metastatic pancreatic cancer (PC). J Clin Oncol 2009;27:4601.","DOI":"10.1200\/jco.2009.27.15_suppl.4601"},{"key":"ref101","doi-asserted-by":"crossref","unstructured":"Middleton G, Valle J, Wadsley J, Propper D, Coxon F, Ross P. A phase III randomized trial of chemoimmunotherapy comprising gemcitabine and capecitabine with or without telomerase vaccine GV1001 in patients with locally advanced or metastatic pancreatic cancer. J Clin Oncol 2013;31:abstr LBA4004.","DOI":"10.1200\/jco.2013.31.18_suppl.lba4004"},{"key":"ref102","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0142(19960801)78:3+&lt;605::AID-CNCR5&gt;3.3.CO;2-B"},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.3109\/00365521.2012.711854"},{"key":"ref104","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djp107"},{"key":"ref105","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-006-0067-0"},{"key":"ref106","doi-asserted-by":"publisher","DOI":"10.2165\/0003495-200868180-00004"},{"key":"ref107","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2008.03.020"},{"key":"ref108","doi-asserted-by":"publisher","DOI":"10.1089\/jpm.2008.9992"},{"key":"ref109","doi-asserted-by":"crossref","unstructured":"Fitzsimmons D, Johnson CD, George S, Payne S, Sandberg AA, Bassi C, Beger HG, Birk D, B&uuml;chler MW, Dervenis C. Development of a disease specific quality of life (QoL) questionnaire module to supplement the EORTC core cancer QoL questionnaire, the QLQ-C30 in patients with pancreatic cancer. EORTC Study Group on Quality of Life. Eur J Cancer 1999;35:939-941.","DOI":"10.1016\/S0959-8049(99)00047-7"},{"key":"ref110","doi-asserted-by":"publisher","DOI":"10.1007\/s00520-012-1713-3"},{"key":"ref111","doi-asserted-by":"publisher","DOI":"10.1002\/art.10515"},{"key":"ref112","doi-asserted-by":"publisher","DOI":"10.1136\/ard.2010.142901"},{"key":"ref113","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa012337"},{"key":"ref114","doi-asserted-by":"publisher","DOI":"10.1097\/01.sla.0000252402.33814.dd"},{"key":"ref115","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa0903048"},{"key":"ref116","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMsa1010705"},{"key":"ref117","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7413"},{"key":"ref118","doi-asserted-by":"publisher","DOI":"10.4045\/tidsskr.11.1242"},{"key":"ref119","doi-asserted-by":"publisher","DOI":"10.4291\/wjgp.v4.i4.74"},{"key":"ref120","doi-asserted-by":"publisher","DOI":"10.4103\/2319-4170.119690"},{"key":"ref121","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.7020"},{"key":"ref122","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i38.5329"},{"key":"ref123","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2012.08.006"},{"key":"ref124","doi-asserted-by":"publisher","DOI":"10.1016\/j.suronc.2013.08.003"},{"key":"ref125","doi-asserted-by":"publisher","DOI":"10.1038\/nrclinonc.2013.66"},{"key":"ref126","doi-asserted-by":"publisher","DOI":"10.1016\/s1470-2045(13)70172-4"},{"key":"ref127","doi-asserted-by":"publisher","DOI":"10.1016\/j.canep.2012.09.001"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v20\/i30\/10405.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,14]],"date-time":"2022-04-14T22:49:10Z","timestamp":1649976550000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v20\/i30\/10405.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":127,"journal-issue":{"issue":"30","published-print":{"date-parts":[[2014]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v20.i30.10405","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2014]]}}}