{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T22:37:50Z","timestamp":1790807870392,"version":"4.1.0"},"reference-count":150,"publisher":"Baishideng Publishing Group Inc.","issue":"26","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2015]]},"DOI":"10.3748\/wjg.v21.i26.7970","type":"journal-article","created":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T02:14:01Z","timestamp":1498097641000},"page":"7970","source":"Crossref","is-referenced-by-count":83,"title":["Management of ampullary neoplasms: A tailored approach between endoscopy and surgery"],"prefix":"10.3748","volume":"21","author":[{"given":"Francesca","family":"Panzeri","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"ref1","unstructured":"Surveillance, Epidemiology and End Results (SEER), SEER stat database: Incidence-SEER regs limited use. Available from: <ext-link ext-link-type=\"uri\" xlink:href=\"http:\/\/www.seer.cancer.gov\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\">http:\/\/www.seer.cancer.gov<\/ext-link>."},{"key":"ref2","unstructured":"Albores-Saavedra J, Henson DE, Klimstra DS. Tumors of the Gallbladder, Extrahepatic Bile Ducts, and Ampulla of Vater - Atlas of Tumor Pathology. Washington, D.C : Armed Forces Institute of Pathology; 1998;."},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19880401)61"},{"key":"ref4","unstructured":"Cattell RB, Pyrtek LJ. Premalignant lesions of the ampulla of Vater. Surg Gynecol Obstet 1950;90:21-30, illust."},{"key":"ref5","unstructured":"Chen WX, Xie QG, Zhang WF, Zhang X, Hu TT, Xu P, Gu ZY. Multiple imaging techniques in the diagnosis of ampullary carcinoma. Hepatobiliary Pancreat Dis Int 2008;7:649-653."},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-007-1275-9"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.057059"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(93)70051-6"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21374"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2000.02094.x"},{"key":"ref11","unstructured":"Bakkevold KE, Arnesj&oslash; B, Kambestad B. Carcinoma of the pancreas and papilla of Vater--assessment of resectability and factors influencing resectability in stage I carcinomas. A prospective multicentre trial in 472 patients. Eur J Surg Oncol 1992;18:494-507."},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198202000-00005"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800741025"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(85)80018-6"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-004-7709-5"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2011.05.012"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000196191.42296.e0"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4787"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-008-0099-4"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejso.2011.06.008"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(19890701)64"},{"key":"ref22","unstructured":"Petrou A, Bramis K, Williams T, Papalambros A, Mantonakis E, Felekouras E. Acute recurrent pancreatitis: a possible clinical manifestation of ampullary cancer. JOP 2011;12:593-597."},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-007-1278-6"},{"key":"ref24","unstructured":"Chen YF, Mai CR, Tie ZJ, Feng ZT, Zhang J, Lu XH, Lu GJ, Xue YH, Pan GZ. The diagnostic significance of carbohydrate antigen CA 19-9 in serum and pancreatic juice in pancreatic carcinoma. Chin Med J (Engl) 1989;102:333-337."},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-8-170"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1977.01370040103016"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(76)90087-8"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199807000-00013"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-198910000-00015"},{"key":"ref30","unstructured":"Cubilla AL, Fitzgerald PJ. Surgical pathology aspects of cancer of the ampulla-head-of-pancreas region. Monogr Pathol 1980;21:67-81."},{"key":"ref31","unstructured":"Tasaka K. Carcinoma in the region of the duodenal papilla. A histopathologic study (author&rsquo;s transl). Fukuoka Igaku Zasshi 1977;68:20-44."},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(97)90048-9"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.1994.tb02077.x"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1002\/jso.22090"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900108"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1007\/s00534-004-0894-7"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-007-0444-1"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1097\/01.pas.0000149708.12335.6a"},{"key":"ref39","unstructured":"Albores-Saavedra J, Henson DE, Klimstra DS. Malignant epithelial tumors of the ampulla. Tumors of the gallbladder, extrahepatic bile ducts, and ampulla of Vater. Washington, D.C : Armed Forces Institute of Pathology; 2000;259-316."},{"key":"ref40","unstructured":"Albores-Saavedra J, Menck HR, Scoazec JC, Sohendra N, Wittekind C, Sriram PVJ, Sripa B. Carcinoma of the gallbladder and extrahepatic bile ducts. Pathology and genetics of tumours of the digestive system Lyon: IARC Press; 2000;206-213."},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.17.5.921"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200407000-00005"},{"key":"ref43","unstructured":"Albores-Saavedra J, Hruban RH, Klimstra DS, Zamboni G. Invasive adenocarcinoma of the ampullary region. WHO Classification of Tumours of the Digestive System Lyon (France): IARC Press; 2010;87-91."},{"key":"ref44","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijscr.2014.04.009"},{"key":"ref45","doi-asserted-by":"publisher","DOI":"10.1097\/01.MP.0000036450.61830.8E"},{"key":"ref46","unstructured":"Kloppel G, Arnold R, Capella D, klimstra J, Albores-Saavedra J, Solcia E, Rindi G, Komminoth P. Neuroendocrine neoplasms of the ampullary region. WHO Classification of Tumours of the Digestive System Lyon (France): IARC Press; 2010;92-94."},{"key":"ref47","unstructured":"Edge SB, Byrd DR, Compton CC, Fritz AG, Greene FL, Trotti A. AJCC Cancer Staging Manual. 7th ed New York: Springer; 2010;."},{"key":"ref48","doi-asserted-by":"crossref","unstructured":"Shirai Y, Tsukada K, Ohtani T, Koyama S, Muto T, Watanabe H, Hatakeyama K. Carcinoma of the ampulla of Vater: histopathologic analysis of tumor spread in Whipple pancreatoduodenectomy specimens. World J Surg 1995;19:102-106; discussion 106-107.","DOI":"10.1007\/BF00316989"},{"key":"ref49","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197505000-00005"},{"key":"ref50","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.134.5.526"},{"key":"ref51","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199705000-00015"},{"key":"ref52","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1991.01410270099016"},{"key":"ref53","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2007.02.049"},{"key":"ref54","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.2009.80"},{"key":"ref55","unstructured":"Key C, Meisner A. Cancers of the Liver and Biliary Tract. SEER Survival Monograph: Cancer Survival Among Adults: U.S. SEER Program, 1988-2001, Patient and Tumor Characteristics Ries LAG: National Cancer Institute, SEER Program; 2007;."},{"key":"ref56","doi-asserted-by":"publisher","DOI":"10.1002\/ssu.10018"},{"key":"ref57","unstructured":"Willett CG, Warshaw AL, Convery K, Compton CC. Patterns of failure after pancreaticoduodenectomy for ampullary carcinoma. Surg Gynecol Obstet 1993;176:33-38."},{"key":"ref58","doi-asserted-by":"publisher","DOI":"10.1007\/BF00198112"},{"key":"ref59","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-006-0213-3"},{"key":"ref60","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2482-2-1"},{"key":"ref61","doi-asserted-by":"publisher","DOI":"10.1002\/jcu.1041"},{"key":"ref62","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-199112000-00010"},{"key":"ref63","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1999.01042.x"},{"key":"ref64","unstructured":"R&ouml;sch T, Braig C, Gain T, Feuerbach S, Siewert JR, Schusdziarra V, Classen M. Staging of pancreatic and ampullary carcinoma by endoscopic ultrasonography. Comparison with conventional sonography, computed tomography, and angiography. Gastroenterology 1992;102:188-199."},{"key":"ref65","doi-asserted-by":"publisher","DOI":"10.1148\/rg.274065047"},{"key":"ref66","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2003.03.555"},{"key":"ref67","doi-asserted-by":"publisher","DOI":"10.1007\/s00261-010-9644-2"},{"key":"ref68","doi-asserted-by":"publisher","DOI":"10.1007\/BF01798360"},{"key":"ref69","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2004.30347.x"},{"key":"ref70","doi-asserted-by":"publisher","DOI":"10.1016\/S0046-8177(85)80129-5"},{"key":"ref71","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1018180"},{"key":"ref72","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(90)71170-4"},{"key":"ref73","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(97)00096-2"},{"key":"ref74","doi-asserted-by":"publisher","DOI":"10.1159\/000286607"},{"key":"ref75","doi-asserted-by":"publisher","DOI":"10.4253\/wjge.v3.i12.241"},{"key":"ref76","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-197803000-00018"},{"key":"ref77","unstructured":"Psathakis D, Utschakowski A, M&uuml;ller G, Broll R, Bruch HP. Clinical significance of duodenal diverticula. J Am Coll Surg 1994;178:257-260."},{"key":"ref78","unstructured":"Osnes M, L&oslash;otveit T, Larsen S, Aune S. Duodenal diverticula and their relationship to age, sex, and biliary calculi. Scand J Gastroenterol 1981;16:103-107."},{"key":"ref79","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(99)70340-8"},{"key":"ref80","doi-asserted-by":"publisher","DOI":"10.1055\/s-2000-86"},{"key":"ref81","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(05)74455-X"},{"key":"ref82","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v16.i44.5592"},{"key":"ref83","doi-asserted-by":"crossref","unstructured":"Mukai H, Yasuda K, Nakajima M. Tumors of the papilla and distal common bile duct. Diagnosis and staging by endoscopic ultrasonography. Gastrointest Endosc Clin N Am 1995;5:763-772.","DOI":"10.1016\/S1052-5157(18)30397-0"},{"key":"ref84","unstructured":"Heinzow HS, Lenz P, Lallier S, Lenze F, Domagk D, Domschke W, Meister T. Ampulla of Vater tumors: impact of intraductal ultrasound and transpapillary endoscopic biopsies on diagnostic accuracy and therapy. Acta Gastroenterol Belg 2011;74:509-515."},{"key":"ref85","doi-asserted-by":"publisher","DOI":"10.1259\/bjr.72.857.10505006"},{"key":"ref86","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD006053.pub4"},{"key":"ref87","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199806000-00005"},{"key":"ref88","doi-asserted-by":"crossref","unstructured":"Roberts RH, Krige JE, Bornman PC, Terblanche J. Pancreaticoduodenectomy of ampullary carcinoma. Am Surg 1999;65:1043-1048.","DOI":"10.1177\/000313489906501110"},{"key":"ref89","doi-asserted-by":"publisher","DOI":"10.1002\/jso.21390"},{"key":"ref90","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(03)00331-4"},{"key":"ref91","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.140.6.529"},{"key":"ref92","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.138.9.941"},{"key":"ref93","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.139.7.718"},{"key":"ref94","doi-asserted-by":"publisher","DOI":"10.1016\/j.surg.2006.07.009"},{"key":"ref95","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2003.07.512"},{"key":"ref96","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-006-9136-3"},{"key":"ref97","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197803)41"},{"key":"ref98","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(03)02366-6"},{"key":"ref99","doi-asserted-by":"publisher","DOI":"10.1055\/s-2005-861287"},{"key":"ref100","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2009.04.015"},{"key":"ref101","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.04.053"},{"key":"ref102","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(04)02029-2"},{"key":"ref103","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-009-0538-8"},{"key":"ref104","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2005.04.020"},{"key":"ref105","doi-asserted-by":"publisher","DOI":"10.1097\/MEG.0000000000000146"},{"key":"ref106","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-014-2543-z"},{"key":"ref107","unstructured":"Bohra AK, McKie L, Diamond T. Transduodenal excision of ampullary tumours. Ulster Med J 2002;71:121-127."},{"key":"ref108","doi-asserted-by":"publisher","DOI":"10.1067\/msy.2000.108218"},{"key":"ref109","unstructured":"Kawabata Y, Ishikawa N, Moriyama I, Tajima Y. What is an adequate surgical management for pTis and pT1 early ampullary carcinoma? Hepatogastroenterology 2014;61:12-17."},{"key":"ref110","doi-asserted-by":"publisher","DOI":"10.1016\/j.anchir.2004.06.001"},{"key":"ref111","doi-asserted-by":"publisher","DOI":"10.1097\/SLA.0b013e318269d010"},{"key":"ref112","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1996.01430160024003"},{"key":"ref113","doi-asserted-by":"publisher","DOI":"10.1016\/S0748-7983(96)90286-3"},{"key":"ref114","doi-asserted-by":"publisher","DOI":"10.1111\/hpb.12297"},{"key":"ref115","doi-asserted-by":"publisher","DOI":"10.1245\/ASO.2005.03.009"},{"key":"ref116","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.2908"},{"key":"ref117","doi-asserted-by":"publisher","DOI":"10.1136\/gut.36.6.853"},{"key":"ref118","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1018181"},{"key":"ref119","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-004-1449-z"},{"key":"ref120","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.04.018"},{"key":"ref121","doi-asserted-by":"publisher","DOI":"10.1186\/1748-717X-6-126"},{"key":"ref122","doi-asserted-by":"publisher","DOI":"10.1016\/j.radonc.2009.05.006"},{"key":"ref123","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199912000-00006"},{"key":"ref124","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2012.7352"},{"key":"ref125","unstructured":"National Comprehensive Cancer Network (NCCN). NCCN Clinical practice guidelines in oncology. Available from: <ext-link ext-link-type=\"uri\" xlink:href=\"http:\/\/www.nccn.org\/professionals\/physician_gls\/f_guidelines.asp\" xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\">http:\/\/www.nccn.org\/professionals\/physician_gls\/f_guidelines.asp<\/ext-link>."},{"key":"ref126","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdp125"},{"key":"ref127","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-009-1080-7"},{"key":"ref128","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-69912010000600008"},{"key":"ref129","doi-asserted-by":"crossref","unstructured":"Choi SB, Kim WB, Song TJ, Suh SO, Kim YC, Choi SY. Surgical outcomes and prognostic factors for ampulla of Vater cancer. Scand J Surg 2011;100:92-98.","DOI":"10.1177\/145749691110000205"},{"key":"ref130","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-011-1175-7"},{"key":"ref131","doi-asserted-by":"publisher","DOI":"10.1111\/j.1349-7006.2000.tb00949.x"},{"key":"ref132","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-013-1995-8"},{"key":"ref133","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.10492"},{"key":"ref134","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181f0b05a"},{"key":"ref135","doi-asserted-by":"publisher","DOI":"10.3346\/jkms.2012.27.5.495"},{"key":"ref136","doi-asserted-by":"publisher","DOI":"10.1016\/S0039-6060(05)80197-7"},{"key":"ref137","doi-asserted-by":"publisher","DOI":"10.1016\/j.jamcollsurg.2008.01.028"},{"key":"ref138","doi-asserted-by":"publisher","DOI":"10.1007\/s00268-004-7498-x"},{"key":"ref139","doi-asserted-by":"publisher","DOI":"10.1007\/s11605-007-0136-9"},{"key":"ref140","doi-asserted-by":"publisher","DOI":"10.5754\/hge10742"},{"key":"ref141","unstructured":"Kawaguchi T, Ochiai T, Ikoma H, Inoue K, Morimura R, Murayama Y, Komatsu S, Shiozaki A, Kuriu Y, Nakanishi M. Prognostic impact of histological blood vessel invasion in patients with ampullary adenocarcinoma. Hepatogastroenterology 2010;57:1347-1350."},{"key":"ref142","doi-asserted-by":"publisher","DOI":"10.1155\/1998\/60259"},{"key":"ref143","doi-asserted-by":"publisher","DOI":"10.4067\/S0034-98872011000800006"},{"key":"ref144","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800821235"},{"key":"ref145","doi-asserted-by":"publisher","DOI":"10.5754\/hge10788"},{"key":"ref146","doi-asserted-by":"publisher","DOI":"10.1007\/s11805-009-0085-z"},{"key":"ref147","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2008.11.045"},{"key":"ref148","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(99)70341-X"},{"key":"ref149","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9610(97)00132-3"},{"key":"ref150","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5107(96)70056-1"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v21\/i26\/7970.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,24]],"date-time":"2023-08-24T03:40:53Z","timestamp":1692848453000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v21\/i26\/7970.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":150,"journal-issue":{"issue":"26","published-print":{"date-parts":[[2015]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v21.i26.7970","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2015]]}}}