{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,14]],"date-time":"2026-05-14T03:17:35Z","timestamp":1778728655493,"version":"3.51.4"},"reference-count":43,"publisher":"Baishideng Publishing Group Inc.","issue":"37","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2016]]},"DOI":"10.3748\/wjg.v22.i37.8349","type":"journal-article","created":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T14:21:14Z","timestamp":1475245274000},"page":"8349","source":"Crossref","is-referenced-by-count":9,"title":["Childhood chronic gastritis and duodenitis: Role of altered sensory neuromediators"],"prefix":"10.3748","volume":"22","author":[{"given":"Ali","family":"Islek","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aygen","family":"Yilmaz","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gulsum Ozlem","family":"Elpek","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nuray","family":"Erin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","unstructured":"Rowland M, Bourke B, Drumm B. Acid-Peptic Disease. Walker&rsquo;s Pediatric Gastrointestinal Disease Hamilton, Ontario, Canada: BC Decker Inc; 2008;153-163."},{"key":"ref2","doi-asserted-by":"crossref","unstructured":"McColl KE, el-Omar E, Gillen D. Helicobacter pylori gastritis and gastric physiology. Gastroenterol Clin North Am 2000;29:687-703, viii.","DOI":"10.1016\/S0889-8553(05)70138-2"},{"key":"ref3","unstructured":"Stead RH. Innervation of mucosal immune cells in the gastrointestinal tract. Reg Immunol 1992;4:91-99."},{"key":"ref4","doi-asserted-by":"crossref","unstructured":"Weinstock JV, Blum AM. Release of substance P by granuloma eosinophils in response to secretagogues in murine schistosomiasis mansoni. Cell Immunol 1990;125:380-385.","DOI":"10.1016\/0008-8749(90)90092-6"},{"key":"ref5","doi-asserted-by":"crossref","unstructured":"Killingsworth CR, Shore SA, Alessandrini F, Dey RD, Paulauskis JD. Rat alveolar macrophages express preprotachykinin gene-I mRNA-encoding tachykinins. Am J Physiol 1997;273:L1073-L1081.","DOI":"10.1152\/ajplung.1997.273.5.L1073"},{"key":"ref6","doi-asserted-by":"crossref","unstructured":"Joos GF, Germonpr&eacute; PR, Pauwels RA. Role of tachykinins in asthma. Allergy 2000;55:321-337.","DOI":"10.1034\/j.1398-9995.2000.00112.x"},{"key":"ref7","unstructured":"Bost KL, Breeding SA, Pascual DW. Modulation of the mRNAs encoding substance P and its receptor in rat macrophages by LPS. Reg Immunol 1992;4:105-112."},{"key":"ref8","doi-asserted-by":"crossref","unstructured":"Erin N, Ercan F, Yegen BC, Arbak S, Okar I, Oktay S. Role of capsaicin-sensitive nerves in gastric and hepatic injury induced by cold-restraint stress. Dig Dis Sci 2000;45:1889-1899.","DOI":"10.1023\/A:1005597220334"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1016\/S0014-827X(03)00060-0"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-006-9085-5"},{"key":"ref11","doi-asserted-by":"crossref","unstructured":"Takeuchi K, Ueshima K, Ohuchi T, Okabe S. The role of capsaicin-sensitive sensory neurons in healing of HCl-induced gastric mucosal lesions in rats. Gastroenterology 1994;106:1524-1532.","DOI":"10.1016\/0016-5085(94)90406-5"},{"key":"ref12","doi-asserted-by":"crossref","unstructured":"Bunnett NW, Wu V, Sternini C, Klinger J, Shimomaya E, Payan D, Kobayashi R, Walsh JH. Distribution and abundance of neutral endopeptidase (EC 3.4.24.11) in the alimentary tract of the rat. Am J Physiol 1993;264:G497-G508.","DOI":"10.1152\/ajpgi.1993.264.3.G497"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.humpath.2004.12.008"},{"key":"ref14","doi-asserted-by":"crossref","unstructured":"Erin N, Clawson GA. Parameters affecting substance P measurement in heart, lung, and skin. Biotechniques 2004;37:232, 234, 236 passim.","DOI":"10.2144\/04372ST04"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.regpep.2008.10.006"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.neulet.2005.09.022"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2012.03.018"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.regpep.2008.10.007"},{"key":"ref19","doi-asserted-by":"crossref","unstructured":"Holzer P, Livingston EH, Saria A, Guth PH. Sensory neurons mediate protective vasodilatation in rat gastric mucosa. Am J Physiol 1991;260:G363-G370.","DOI":"10.1152\/ajpgi.1991.260.3.G363"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Pernow B. Substance P--a putative mediator of antidromic vasodilation. Gen Pharmacol 1983;14:13-16.","DOI":"10.1016\/0306-3623(83)90055-1"},{"key":"ref21","doi-asserted-by":"crossref","unstructured":"Reinshagen M, Patel A, Sottili M, French S, Sternini C, Eysselein VE. Action of sensory neurons in an experimental at colitis model of injury and repair. Am J Physiol 1996;270:G79-G86.","DOI":"10.1152\/ajpgi.1996.270.1.G79"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1556\/ABiol.54.2003.3-4.6"},{"key":"ref23","unstructured":"Ottaway CA, Stanisz AM. Neural-immune interactions in the intestine: Implications for inflammatory bowel disease. Inflammatory bowel disease Baltimore: Williams and Wilkins; 1995;281-300."},{"key":"ref24","doi-asserted-by":"crossref","unstructured":"K&auml;hler CM, Sitte BA, Reinisch N, Wiedermann CJ. Stimulation of the chemotactic migration of human fibroblasts by substance P. Eur J Pharmacol 1993;249:281-286.","DOI":"10.1016\/0014-2999(93)90523-K"},{"key":"ref25","doi-asserted-by":"crossref","unstructured":"Ansel JC, Brown JR, Payan DG, Brown MA. Substance P selectively activates TNF-alpha gene expression in murine mast cells. J Immunol 1993;150:4478-4485.","DOI":"10.4049\/jimmunol.150.10.4478"},{"key":"ref26","doi-asserted-by":"crossref","unstructured":"Cocchiara R, Bongiovanni A, Albeggiani G, Azzolina A, Geraci D. Substance P selectively activates TNF-alpha mRNA in rat uterine immune cells: a neuroimmune link. Neuroreport 1997;8:2961-2964.","DOI":"10.1097\/00001756-199709080-00031"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1124\/pr.56.2.7"},{"key":"ref28","doi-asserted-by":"crossref","unstructured":"Harmar AJ, Arimura A, Gozes I, Journot L, Laburthe M, Pisegna JR, Rawlings SR, Robberecht P, Said SI, Sreedharan SP. International Union of Pharmacology. XVIII. Nomenclature of receptors for vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide. Pharmacol Rev 1998;50:265-270.","DOI":"10.1016\/S0031-6997(24)01360-7"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0143661"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.1089\/jmf.2015.3570"},{"key":"ref31","unstructured":"Domschke S, Bloom SR, Adrian TE, Lux G, Bryant MG, Domschke W. Gastroduodenal mucosal hormone content in duodenal ulcer disease. Hepatogastroenterology 1985;32:198-201."},{"key":"ref32","doi-asserted-by":"crossref","unstructured":"Yao B, Hogan DL, Bukhave K, Koss MA, Isenberg JI. Bicarbonate transport by rabbit duodenum in vitro: effect of vasoactive intestinal polypeptide, prostaglandin E2, and cyclic adenosine monophosphate. Gastroenterology 1993;104:732-740.","DOI":"10.1016\/0016-5085(93)91008-6"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-006-9180-7"},{"key":"ref34","doi-asserted-by":"crossref","unstructured":"Clementi G, Amico-Roxas M, Caruso A, Cutuli VM, Maugeri S, Prato A. Protective effects of calcitonin gene-related peptide in different experimental models of gastric ulcers. Eur J Pharmacol 1993;238:101-104.","DOI":"10.1016\/0014-2999(93)90511-F"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-012-2362-6"},{"key":"ref36","doi-asserted-by":"crossref","unstructured":"Evangelista S. Capsaicin receptor as target of calcitonin gene-related peptide in the gut. Prog Drug Res 2014;68:259-276.","DOI":"10.1007\/978-3-0348-0828-6_10"},{"key":"ref37","doi-asserted-by":"crossref","unstructured":"Trejdosiewicz LK, Malizia G, Oakes J, Losowsky MS, Janossy G. Expression of the common acute lymphoblastic leukaemia antigen (CALLA gp100) in the brush border of normal jejunum and jejunum of patients with coeliac disease. J Clin Pathol 1985;38:1002-1006.","DOI":"10.1136\/jcp.38.9.1002"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1111\/j.1083-4389.2004.00253.x"},{"key":"ref39","doi-asserted-by":"crossref","unstructured":"Danielsen EM, Vyas JP, Kenny AJ. A neutral endopeptidase in the microvillar membrane of pig intestine. Partial purification and properties. Biochem J 1980;191:645-648.","DOI":"10.1042\/bj1910645"},{"key":"ref40","doi-asserted-by":"crossref","unstructured":"Groisman GM, Amar M, Livne E. CD10: a valuable tool for the light microscopic diagnosis of microvillous inclusion disease (familial microvillous atrophy). Am J Surg Pathol 2002;26:902-907.","DOI":"10.1097\/00000478-200207000-00008"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e3181e11e4b"},{"key":"ref42","doi-asserted-by":"publisher","DOI":"10.1038\/modpathol.2011.122"},{"key":"ref43","doi-asserted-by":"crossref","unstructured":"Endoh Y, Tamura G, Motoyama T, Ajioka Y, Watanabe H. Well-differentiated adenocarcinoma mimicking complete-type intestinal metaplasia in the stomach. Hum Pathol 1999;30:826-832.","DOI":"10.1016\/S0046-8177(99)90144-2"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v22\/i37\/8349.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,10]],"date-time":"2025-06-10T22:09:55Z","timestamp":1749593395000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.wjgnet.com\/1007-9327\/full\/v22\/i37\/8349.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016]]},"references-count":43,"journal-issue":{"issue":"37","published-print":{"date-parts":[[2016]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v22.i37.8349","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2016]]}}}