{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T14:21:24Z","timestamp":1779200484593,"version":"3.51.4"},"reference-count":40,"publisher":"Baishideng Publishing Group Inc.","issue":"14","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2020,4,14]]},"DOI":"10.3748\/wjg.v26.i14.1601","type":"journal-article","created":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T08:08:28Z","timestamp":1586851708000},"page":"1601-1612","source":"Crossref","is-referenced-by-count":17,"title":["Silymarin, boswellic acid and curcumin enriched dietetic formulation reduces the growth of inherited intestinal polyps in an animal model"],"prefix":"10.3748","volume":"26","author":[{"given":"Bruna","family":"Girardi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria","family":"Pricci","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Floriana","family":"Giorgio","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariano","family":"Piazzolla","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrea","family":"Iannone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Giuseppe","family":"Losurdo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariabeatrice","family":"Principi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michele","family":"Barone","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Enzo","family":"Ierardi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alfredo Di","family":"Leo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(13)61649-9"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.2002.02120.x"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0804588"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1111\/codi.12318"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-308075"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2007.10.018"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2017.08.015"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgp275"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgw041"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12912"},{"key":"ref11","unstructured":"Pellegrini L, Milano E, Franceschi F, Belcaro G, Gizzi G, Feragalli B, Dugall M, Luzzi R, Togni S, Eggenhoffner R, Giacomelli L. Managing ulcerative colitis in remission phase: usefulness of Casperome\u00ae, an innovative lecithin-based delivery system of Boswellia serrata extract. Eur Rev Med Pharmacol Sci 2016; 20: 2695-2700"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.27929"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.5582\/ddt.8.25"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1352.010"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1080\/10408398.2016.1252711"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2018.05.031"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.1080\/01635581003693082"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-008-9734-9"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgy104"},{"key":"ref20","unstructured":"Kidd PM. Bioavailability and activity of phytosome complexes from botanical polyphenols: the silymarin, curcumin, green tea, and grape seed extracts. Altern Med Rev 2009; 14: 226-246"},{"key":"ref21","unstructured":"National Research Council (US) Committee for the Update of the Guide for the Care and Use of Laboratory Animals. Guide for the Care and Use of Laboratory Animals. 8th edition. Washington (DC): National Academies Press (US); 2011"},{"key":"ref22","unstructured":"Associazione Italiana per le Scienze degli Animali da Laboratorio. Dati Sulla Sperimentazione. [accessed 2020 Jan 3] Available from: https:\/\/www.aisal.org\/normative-dati-risorse\/dati-sulla-sperimentazione\/"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2014.07.039"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgh346"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1126\/science.1350108"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-3603-8_27"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-4939-3603-8_27"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i33.11496"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i34.5671"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v22.i11.3202"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgs286"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.6226"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.26355\/eurrev_201904_17591"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1159\/000141762"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1172\/JCI104769"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-018-0081-y"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i27.4325"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1007\/7651_2015_197"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-09-3249"},{"key":"ref40","unstructured":"Perkins S, Verschoyle RD, Hill K, Parveen I, Threadgill MD, Sharma RA, Williams ML, Steward WP, Gescher AJ. Chemopreventive efficacy and pharmacokinetics of curcumin in the min\/+ mouse, a model of familial adenomatous polyposis. Cancer Epidemiol Biomarkers Prev 2002; 11: 535-540"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i14\/1601.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,4,14]],"date-time":"2020-04-14T08:08:38Z","timestamp":1586851718000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i14\/1601.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,4,14]]},"references-count":40,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2020,4,14]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v26.i14.1601","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2020,4,14]]}}}