{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T04:32:21Z","timestamp":1788582741049,"version":"build-2803163510"},"reference-count":41,"publisher":"Baishideng Publishing Group Inc.","issue":"20","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2020,5,28]]},"DOI":"10.3748\/wjg.v26.i20.2584","type":"journal-article","created":{"date-parts":[[2020,5,28]],"date-time":"2020-05-28T09:44:16Z","timestamp":1590659056000},"page":"2584-2598","source":"Crossref","is-referenced-by-count":17,"title":["Conservation and variability of hepatitis B core at different chronic hepatitis stages"],"prefix":"10.3748","volume":"26","author":[{"given":"Mar\u00e7al","family":"Yll","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria Francesca","family":"Cortese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mercedes","family":"Guerrero-Murillo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerard","family":"Orriols","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Gregori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosario","family":"Casillas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carolina","family":"Gonz\u00e1lez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sara","family":"Sopena","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Godoy","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marta","family":"Vila","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Tabernero","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Josep","family":"Quer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariadna","family":"Rando","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rosa","family":"Lopez-Martinez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rafael","family":"Esteban","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mar","family":"Riveiro-Barciela","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria","family":"Buti","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Francisco","family":"Rodr\u00edguez-Fr\u00edas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"ref1","unstructured":"World Health Organization. Global Hepatitis Report, 2017. World Heal Organ [Internet] 2017; 62. Available from: URL: http:\/\/www.who.int\/hepatitis"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2018.35"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.3390\/v9060156"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v21.i15.4644"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.01.002"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0057525"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2015.06.019"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.03131-14"},{"key":"ref9","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i19.2095"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.3851\/IMP1619"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1016\/0022-2836(92)90101-o"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2017.11.015"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2015.06.020"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00272-18"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-33051-4"},{"key":"ref16","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.03.021"},{"key":"ref17","unstructured":"Team RC. A language and environment for statistical computing. R Found. Stat. Comput. Vienna, Austria. 2016; Available from: URL: https:\/\/www.r-project.org\/"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2013.03.007"},{"key":"ref19","unstructured":"Cuadras C. A distance approach to discriminant analysis and its properties. In: Mathematics preprint series. Barcelona: 1991"},{"key":"ref20","doi-asserted-by":"crossref","unstructured":"Cuadras C. Distance analysis in discrimination and classification using both continuous and categorical variables. In: Statistical AData analysis and Interference. Amsterdam, 1989: 459-473","DOI":"10.1016\/B978-0-444-88029-1.50047-2"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1007\/bf01731581"},{"key":"ref22","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-309809"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1080\/13543784.2017.1333105"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1080\/14712598.2018.1472231"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.bpg.2017.05.002"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02120-17"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1001162"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1111\/apt.15108"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmi.2017.03.003"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.7150\/thno.25958"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2014.1908"},{"key":"ref32","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00466-15"},{"key":"ref33","doi-asserted-by":"publisher","DOI":"10.3390\/mi10020129"},{"key":"ref34","doi-asserted-by":"publisher","DOI":"10.1038\/srep42794"},{"key":"ref35","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00394-16"},{"key":"ref36","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007085"},{"key":"ref37","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2018.9620"},{"key":"ref38","doi-asserted-by":"publisher","DOI":"10.1002\/cam4.2169"},{"key":"ref39","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-18-1127"},{"key":"ref40","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2018.00355"},{"key":"ref41","doi-asserted-by":"publisher","DOI":"10.1099\/jgv.0.000790"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i20\/2584.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,5,28]],"date-time":"2020-05-28T09:44:20Z","timestamp":1590659060000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i20\/2584.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,28]]},"references-count":41,"journal-issue":{"issue":"20","published-print":{"date-parts":[[2020,5,28]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v26.i20.2584","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2020,5,28]]}}}