{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T21:35:27Z","timestamp":1774647327356,"version":"3.50.1"},"reference-count":31,"publisher":"Baishideng Publishing Group Inc.","issue":"35","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2020,9,21]]},"DOI":"10.3748\/wjg.v26.i35.5314","type":"journal-article","created":{"date-parts":[[2020,9,15]],"date-time":"2020-09-15T05:25:47Z","timestamp":1600147547000},"page":"5314-5327","source":"Crossref","is-referenced-by-count":5,"title":["Investigation of immune escape-associated mutations of hepatitis B virus in patients harboring hepatitis B virus drug-resistance mutations"],"prefix":"10.3748","volume":"26","author":[{"given":"Bi-Xia","family":"Huang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhen-Ping","family":"Fan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lan-Lan","family":"Si","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rong-Juan","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jun","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dan","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fu-Sheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dong-Ping","family":"Xu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xin-Guang","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","reference":[{"key":"ref1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(18)30056-6"},{"key":"ref2","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2018.3795"},{"key":"ref3","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21698"},{"key":"ref4","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22841"},{"key":"ref5","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12069"},{"key":"ref6","doi-asserted-by":"publisher","DOI":"10.1016\/j.bjid.2015.12.006"},{"key":"ref7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.02.006"},{"key":"ref8","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2016.04.015"},{"key":"ref9","doi-asserted-by":"crossref","unstructured":"Carrou\u00e9e-Durantel S, Durantel D, Werle-Lapostolle B, Pichoud C, Naesens L, Neyts J, Tr\u00e9po C, Zoulim F. Suboptimal response to adefovir dipivoxil therapy for chronic hepatitis B in nucleoside-naive patients is not due to pre-existing drug-resistant mutants. Antivir Ther 2008; 13: 381-388","DOI":"10.1177\/135965350801300317"},{"key":"ref10","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.07.011"},{"key":"ref11","doi-asserted-by":"publisher","DOI":"10.1038\/emi.2017.2"},{"key":"ref12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2017.03.027"},{"key":"ref13","doi-asserted-by":"publisher","DOI":"10.1186\/s12879-018-3161-2"},{"key":"ref14","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2018.04.003"},{"key":"ref15","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2019.104579"},{"key":"ref16","unstructured":"Ganji A, Esmaeilzadeh A, Ghafarzadegan K, Helalat H, Rafatpanah H, Mokhtarifar A. Correlation between HBsAg quantitative assay results and HBV DNA levels in chronic HBV. Hepat Mon 2011; 11: 342-345"},{"key":"ref17","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i14.1507"},{"key":"ref18","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2013.11.015"},{"key":"ref19","doi-asserted-by":"publisher","DOI":"10.3851\/IMP3156"},{"key":"ref20","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0155654"},{"key":"ref21","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.24936"},{"key":"ref22","doi-asserted-by":"crossref","unstructured":"Chinese Society of Hepatology, Chinese Medical Association. Chinese Society of Infectious Diseases, Chinese Medical Association. Guideline on prevention and treatment of chronic hepatitis B in China (2005). Chin Med J (Engl) 2007; 120: 2159-2173","DOI":"10.1097\/00029330-200712020-00002"},{"key":"ref23","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcv.2010.05.010"},{"key":"ref24","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2019.1584018"},{"key":"ref25","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2019.02.012"},{"key":"ref26","doi-asserted-by":"publisher","DOI":"10.3851\/IMP3305"},{"key":"ref27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.04.041"},{"key":"ref28","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-017-9817-y"},{"key":"ref29","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27650"},{"key":"ref30","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v24.i31.3488"},{"key":"ref31","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01796-09"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i35\/5314.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,11,18]],"date-time":"2022-11-18T08:27:56Z","timestamp":1668760076000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i35\/5314.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,9,21]]},"references-count":31,"journal-issue":{"issue":"35","published-print":{"date-parts":[[2020,9,21]]}},"URL":"https:\/\/doi.org\/10.3748\/wjg.v26.i35.5314","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2020,9,21]]}}}