{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T16:32:55Z","timestamp":1792513975436,"version":"4.5.0"},"reference-count":258,"publisher":"Baishideng Publishing Group Inc.","issue":"40","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2020,10,28]]},"DOI":"10.3748\/wjg.v26.i40.6111","type":"journal-article","created":{"date-parts":[[2020,10,28]],"date-time":"2020-10-28T07:23:57Z","timestamp":1603869837000},"page":"6111-6140","source":"Crossref","is-referenced-by-count":107,"title":["Cirrhotic portal hypertension: From pathophysiology to novel therapeutics"],"prefix":"10.3748","volume":"26","author":[{"given":"Lakmie S","family":"Gunarathne","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Harinda","family":"Rajapaksha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Shackel","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter W","family":"Angus","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chandana B","family":"Herath","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(19)30349-8"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1016\/s1089-3261(05)70186-0"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.08.013"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-8278(00)80422-5"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.09.009"},{"key":"B6","unstructured":"Abraldes JG, Bosch J. Clinical Features and Natural History of Variceal Hemorrhage. In: Sanyal AJ, Shah VH. Portal Hypertension Clinical Gastroenterology. Totwa, NJ: Humana Press Inc., 2005: 3-15"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.05.024"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra0707185"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-122-7-199504010-00008"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.107789"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840080532"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.03.007"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510280339"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22273"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(85)90214-8"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-194510000-00001"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.qjmed.a066937"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1136\/gut.4.2.95"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1172\/JCI24282"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.2174\/092986706779026138"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.4291\/wjgp.v4.i1.1"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.06.036"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2019.01169"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00045.2009"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00163.2012"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.03.013"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v2.i6.208"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1097\/01.mcg.0000155552.14396.3d"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.01.003"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.31432"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-011110-130246"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1016\/S1665-2681(19)31740-5"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(00)70368-4"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.36561"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.03.008"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1007\/s00005-014-0310-1"},{"key":"B37","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8566602"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27343"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2011.02579.x"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-804274-8.00034-5"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(00)70379-9"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(98)70487-1"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(99)70408-7"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1038\/nm1289"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(03)00909-0"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21228"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21673"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510290436"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00336.2005"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2003.50304"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1136\/gut.44.5.749"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510240432"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1042\/CS20120030"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-8278(96)80124-3"},{"key":"B55","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510280604"},{"key":"B56","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840170116"},{"key":"B57","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.12119"},{"key":"B58","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2005.01092.x"},{"key":"B59","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(93)90655-v"},{"key":"B60","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(96)70026-4"},{"key":"B61","doi-asserted-by":"publisher","DOI":"10.1016\/0270-9139(95)90119-1"},{"key":"B62","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.063735"},{"key":"B63","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510230118"},{"key":"B64","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00145.2002"},{"key":"B65","doi-asserted-by":"publisher","DOI":"10.1159\/000462974"},{"key":"B66","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840020208"},{"key":"B67","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8613060"},{"key":"B68","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840180322"},{"key":"B69","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00538.2007"},{"key":"B70","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20817"},{"key":"B71","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.94.12.3341"},{"key":"B72","doi-asserted-by":"publisher","DOI":"10.1159\/000025562"},{"key":"B73","doi-asserted-by":"publisher","DOI":"10.1097\/00005344-199611000-00014"},{"key":"B74","doi-asserted-by":"publisher","DOI":"10.1016\/s0006-2952(97)00039-7"},{"key":"B75","doi-asserted-by":"publisher","DOI":"10.1016\/s1098-8823(03)00077-7"},{"key":"B76","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20993"},{"key":"B77","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v19.i13.2065"},{"key":"B78","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(61)91879-7"},{"key":"B79","doi-asserted-by":"publisher","DOI":"10.1016\/0024-3205(89)90019-2"},{"key":"B80","doi-asserted-by":"publisher","DOI":"10.1042\/CS20080647"},{"key":"B81","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21502"},{"key":"B82","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.029"},{"key":"B83","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2362.2003.01131.x"},{"key":"B84","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2018.08.008"},{"key":"B85","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2008.12.011"},{"key":"B86","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22758"},{"key":"B87","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2009.06.024"},{"key":"B88","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0016978"},{"key":"B89","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.088013"},{"key":"B90","unstructured":"Kumar A, Sharma P, Sarin SK. Hepatic venous pressure gradient measurement: time to learn! Indian J Gastroenterol 2008; 27: 74-80"},{"key":"B91","unstructured":"Garcia-Tsao G. The Use of Nonselective Beta Blockers for Treatment of Portal Hypertension. Gastroenterol Hepatol 13: 617-619"},{"key":"B92","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2000.19322"},{"key":"B93","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20062"},{"key":"B94","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.1998.275.3.G410"},{"key":"B95","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2015.02.001"},{"key":"B96","doi-asserted-by":"publisher","DOI":"10.3233\/DMA-2011-0835"},{"key":"B97","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/6183714"},{"key":"B98","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2014.12.029"},{"key":"B99","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2016.10.024"},{"key":"B100","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01481.x"},{"key":"B101","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2036.2004.02109.x"},{"key":"B102","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2012.02830.x"},{"key":"B103","doi-asserted-by":"publisher","DOI":"10.1093\/gastro\/gox007"},{"key":"B104","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(81)90144-X"},{"key":"B105","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840220145"},{"key":"B106","doi-asserted-by":"publisher","DOI":"10.1159\/000374100"},{"key":"B107","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9270(02)06016-1"},{"key":"B108","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198112033052302"},{"key":"B109","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM198710013171403"},{"key":"B110","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199105303242202"},{"key":"B111","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840070306"},{"key":"B112","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840080103"},{"key":"B113","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-117-1-59"},{"key":"B114","doi-asserted-by":"publisher","DOI":"10.1172\/JCI115062"},{"key":"B115","unstructured":"Ohnishi K, Nakayama T, Saito M, Hatano H, Tsukamoto T, Terabayashi H, Sugita S, Wada K, Nomura F, Koen H. Effects of propranolol on portal hemodynamics in patients with chronic liver disease. Am J Gastroenterol 1985; 80: 132-135"},{"key":"B116","doi-asserted-by":"publisher","DOI":"10.1016\/S0168-8278(87)80012-0"},{"key":"B117","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa044456"},{"key":"B118","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.05.022"},{"key":"B119","doi-asserted-by":"publisher","DOI":"10.1002\/hep.28906"},{"key":"B120","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-309262"},{"key":"B121","doi-asserted-by":"publisher","DOI":"10.1097\/00042737-199911000-00006"},{"key":"B122","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1007133"},{"key":"B123","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21907"},{"key":"B124","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(01)81028-3"},{"key":"B125","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2013.09.016"},{"key":"B126","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.191"},{"key":"B127","doi-asserted-by":"publisher","DOI":"10.1016\/s1665-2681(19)32023-x"},{"key":"B128","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23775"},{"key":"B129","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2014.03.005"},{"key":"B130","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgast-2016-000104"},{"key":"B131","doi-asserted-by":"publisher","DOI":"10.1002\/9780470760154.CH12"},{"key":"B132","doi-asserted-by":"publisher","DOI":"10.1111\/liv.12360"},{"key":"B133","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1997.v112.pm9178694"},{"key":"B134","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(90)91168-6"},{"key":"B135","doi-asserted-by":"publisher","DOI":"10.1111\/apt.12634"},{"key":"B136","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510300124"},{"key":"B137","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23689"},{"key":"B138","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-304182"},{"key":"B139","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.36947"},{"key":"B140","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.291.6495.561"},{"key":"B141","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD011510.pub2"},{"key":"B142","unstructured":"Trust KsCHN. Beta-blockers for Oesophageal Varices (BOPPP). [accessed 2018 Dec 17]. In: ClinicalTrials.gov [Internet]. Bethesda (MD): U.S. National Library of Medicine. Available from: http:\/\/clinicaltrials.gov\/show\/NCT03776955 ClinicalTrials.gov Identifier: NCT03776955"},{"key":"B143","doi-asserted-by":"publisher","DOI":"10.1136\/bmjgast-2019-000290"},{"key":"B144","doi-asserted-by":"publisher","DOI":"10.1136\/gut.25.1.73"},{"key":"B145","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840020503"},{"key":"B146","doi-asserted-by":"publisher","DOI":"10.1136\/gut.26.4.421"},{"key":"B147","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840020602"},{"key":"B148","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD002147"},{"key":"B149","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840150609"},{"key":"B150","doi-asserted-by":"publisher","DOI":"10.1517\/14656560903207019"},{"key":"B151","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-014-9594-9"},{"key":"B152","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2018.03.024"},{"key":"B153","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i11.1166"},{"key":"B154","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.20892"},{"key":"B155","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2002.36945"},{"key":"B156","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-114-10-869"},{"key":"B157","doi-asserted-by":"publisher","DOI":"10.1002\/hep.1840200310"},{"key":"B158","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(98)70372-5"},{"key":"B159","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.04.025"},{"key":"B160","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.01.020"},{"key":"B161","doi-asserted-by":"publisher","DOI":"10.1038\/srep14573"},{"key":"B162","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2017.04.039"},{"key":"B163","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.01.043"},{"key":"B164","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2016.01.004"},{"key":"B165","doi-asserted-by":"publisher","DOI":"10.1016\/S2468-1253(19)30320-6"},{"key":"B166","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2009.661"},{"key":"B167","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21080"},{"key":"B168","doi-asserted-by":"publisher","DOI":"10.1002\/hep.27679"},{"key":"B169","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.112.040469"},{"key":"B170","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2010.03.021"},{"key":"B171","doi-asserted-by":"publisher","DOI":"10.1016\/0016-5085(92)91807-G"},{"key":"B172","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-116-6-515"},{"key":"B173","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v23.i19.3396"},{"key":"B174","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.109.145839"},{"key":"B175","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2008.05461.x"},{"key":"B176","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2014.00113"},{"key":"B177","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00037.2003"},{"key":"B178","doi-asserted-by":"publisher","DOI":"10.1172\/JCI117251"},{"key":"B179","doi-asserted-by":"publisher","DOI":"10.1161\/hy09t1.094234"},{"key":"B180","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfi265"},{"key":"B181","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.87.5.e1"},{"key":"B182","doi-asserted-by":"publisher","DOI":"10.1016\/s1050-1738(02)00233-5"},{"key":"B183","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2004.03.001"},{"key":"B184","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M200581200"},{"key":"B185","doi-asserted-by":"publisher","DOI":"10.1021\/bi035268s"},{"key":"B186","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000094733.61689.D4"},{"key":"B187","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20040634"},{"key":"B188","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.19.6.692"},{"key":"B189","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.11.4095"},{"key":"B190","doi-asserted-by":"crossref","unstructured":"Chappell MC, Brosnihan KB, Diz DI, Ferrario CM. Identification of angiotensin-(1-7) in rat brain. Evidence for differential processing of angiotensin peptides. J Biol Chem 1989; 264: 16518-16523","DOI":"10.1016\/S0021-9258(19)84737-3"},{"key":"B191","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.18.5_suppl.iii126"},{"key":"B192","doi-asserted-by":"crossref","unstructured":"Mahon JM, Carr RD, Nicol AK, Henderson IW. Angiotensin(1-7) is an antagonist at the type 1 angiotensin II receptor. J Hypertens 1994; 12: 1377-1381","DOI":"10.1097\/00004872-199412000-00010"},{"key":"B193","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.1995.269.1.H313"},{"key":"B194","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.31.1.356"},{"key":"B195","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1434"},{"key":"B196","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000013847.07035.b9"},{"key":"B197","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01170.2005"},{"key":"B198","doi-asserted-by":"publisher","DOI":"10.1016\/j.regpep.2012.01.001"},{"key":"B199","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2017.6848"},{"key":"B200","doi-asserted-by":"publisher","DOI":"10.1111\/j.1476-5381.1994.tb14014.x"},{"key":"B201","unstructured":"Santos RA, Baracho NC. Angiotensin-(1-7) is a potent antidiuretic peptide in rats. Braz J Med Biol Res 1992; 25: 651-654"},{"key":"B202","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ki.5001509"},{"key":"B203","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.90437.2008"},{"key":"B204","doi-asserted-by":"publisher","DOI":"10.1159\/000108758"},{"key":"B205","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.29.1.394"},{"key":"B206","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.27.3.523"},{"key":"B207","doi-asserted-by":"publisher","DOI":"10.1016\/s0196-9781(99)00123-0"},{"key":"B208","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.37.1.72"},{"key":"B209","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000251865.35728.2f"},{"key":"B210","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.110.204453"},{"key":"B211","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.26.6.1154"},{"key":"B212","doi-asserted-by":"publisher","DOI":"10.1016\/s0196-9781(02)00080-3"},{"key":"B213","doi-asserted-by":"publisher","DOI":"10.1139\/y06-053"},{"key":"B214","doi-asserted-by":"publisher","DOI":"10.1016\/0361-9230(94)90104-X"},{"key":"B215","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.29.1.388"},{"key":"B216","doi-asserted-by":"publisher","DOI":"10.1161\/01.hyp.0000037979.53963.8f"},{"key":"B217","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1432869100"},{"key":"B218","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0b013e3282f0143c"},{"key":"B219","doi-asserted-by":"publisher","DOI":"10.1016\/j.jash.2008.05.003"},{"key":"B220","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.107.102764"},{"key":"B221","doi-asserted-by":"publisher","DOI":"10.1161\/01.HYP.0000215289.51180.5c"},{"key":"B222","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.108.114280"},{"key":"B223","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2006.10.007"},{"key":"B224","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.113.301077"},{"key":"B225","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-008-9884-4"},{"key":"B226","doi-asserted-by":"publisher","DOI":"10.1161\/HYPERTENSIONAHA.116.07572"},{"key":"B227","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.144584"},{"key":"B228","doi-asserted-by":"publisher","DOI":"10.1111\/j.1872-034X.2009.00581.x"},{"key":"B229","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-8278(01)00146-5"},{"key":"B230","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2004.062398"},{"key":"B231","doi-asserted-by":"publisher","DOI":"10.1002\/hep.20665"},{"key":"B232","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.25480"},{"key":"B233","doi-asserted-by":"publisher","DOI":"10.1159\/000069792"},{"key":"B234","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.17.5.899"},{"key":"B235","doi-asserted-by":"publisher","DOI":"10.1172\/JCI18212"},{"key":"B236","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-8278(02)00104-6"},{"key":"B237","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v6.i6.824"},{"key":"B238","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2015.92"},{"key":"B239","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.1991.tb01816.x"},{"key":"B240","doi-asserted-by":"publisher","DOI":"10.1097\/01.Ccm.0000178173.27923.Eb"},{"key":"B241","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2005.088633"},{"key":"B242","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.15.2512"},{"key":"B243","doi-asserted-by":"publisher","DOI":"10.1053\/jhep.2001.28794"},{"key":"B244","doi-asserted-by":"publisher","DOI":"10.1016\/j.gtc.2010.08.015"},{"key":"B245","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.1992.262.6.G996"},{"key":"B246","doi-asserted-by":"publisher","DOI":"10.1016\/s0008-6363(98)00008-x"},{"key":"B247","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2009.02181.x"},{"key":"B248","doi-asserted-by":"publisher","DOI":"10.1002\/1098-1128(200101)21:1<1::aid-med1>3.0.co;2-6"},{"key":"B249","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9343(84)90887-8"},{"key":"B250","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-003-1222-8"},{"key":"B251","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.1995.tb01090.x"},{"key":"B252","unstructured":"Svoboda P, Ochmann J, Kantorov\u00e1 I. Effect of enalapril treatment and sclerotherapy of esophageal varices on hepatic hemodynamics in portal hypertension. Hepatogastroenterology 1992; 39: 549-552"},{"key":"B253","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2007.03.014"},{"key":"B254","doi-asserted-by":"publisher","DOI":"10.1111\/j.1572-0241.2007.01759.x"},{"key":"B255","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.26295"},{"key":"B256","doi-asserted-by":"publisher","DOI":"10.1111\/j.1478-3231.2012.02774.x"},{"key":"B257","doi-asserted-by":"publisher","DOI":"10.1177\/1470320316628717"},{"key":"B258","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.01145.2002"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i40\/6111.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2021,4,11]],"date-time":"2021-04-11T00:15:16Z","timestamp":1618100116000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i40\/6111.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,10,28]]},"references-count":258,"journal-issue":{"issue":"40"},"URL":"https:\/\/doi.org\/10.3748\/wjg.v26.i40.6111","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2020,10,28]]}}}