{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,27]],"date-time":"2026-06-27T01:09:02Z","timestamp":1782522542547,"version":"3.54.5"},"reference-count":54,"publisher":"Baishideng Publishing Group Inc.","issue":"45","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["WJG"],"published-print":{"date-parts":[[2020,12,7]]},"DOI":"10.3748\/wjg.v26.i45.7131","type":"journal-article","created":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T04:31:36Z","timestamp":1607056296000},"page":"7131-7152","source":"Crossref","is-referenced-by-count":16,"title":["Nimbolide inhibits tumor growth by restoring hepatic tight junction protein expression and reduced inflammation in an experimental hepatocarcinogenesis"],"prefix":"10.3748","volume":"26","author":[{"given":"Amit Kumar","family":"Ram","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Balasubramaniyan","family":"Vairappan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"BH","family":"Srinivas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.08.025"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1055\/s-0038-1676806"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1016\/j.ctrv.2019.101946"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2015.09.007"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamem.2020.183279"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a002584"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2407-4-10"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2015.06.015"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.103.3.755"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.273.45.29745"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2148-10-93"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1016\/j.proghi.2007.01.001"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.90.16.7834"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.556449"},{"key":"B15","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.200210020"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2004.08.008"},{"key":"B17","unstructured":"Kaihara T, Kusaka T, Nishi M, Kawamata H, Imura J, Kitajima K, Itoh-Minami R, Aoyama N, Kasuga M, Oda Y, Hattori M, Fujimori T. Dedifferentiation and decreased expression of adhesion molecules, E-cadherin and ZO-1, in colorectal cancer are closely related to liver metastasis. J Exp Clin Cancer Res 2003; 22: 117-123"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1097\/00006676-200110000-00006"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.11.12.4131"},{"key":"B20","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-018-4484-5"},{"key":"B21","doi-asserted-by":"publisher","DOI":"10.1039\/C1967000808A"},{"key":"B22","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-016-2898-4"},{"key":"B23","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2012.10.008"},{"key":"B24","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-008-9170-z"},{"key":"B25","doi-asserted-by":"publisher","DOI":"10.1038\/srep22192"},{"key":"B26","doi-asserted-by":"publisher","DOI":"10.1089\/ars.2015.6418"},{"key":"B27","doi-asserted-by":"publisher","DOI":"10.1038\/srep19819"},{"key":"B28","doi-asserted-by":"publisher","DOI":"10.1007\/s13277-015-3477-0"},{"key":"B29","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-017-4132-1"},{"key":"B30","doi-asserted-by":"publisher","DOI":"10.1080\/10715760902870637"},{"key":"B31","doi-asserted-by":"publisher","DOI":"10.4143\/crt.2014.321"},{"key":"B32","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1570"},{"key":"B33","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0228857"},{"key":"B34","doi-asserted-by":"publisher","DOI":"10.7150\/jca.39972"},{"key":"B35","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7819-11-212"},{"key":"B36","doi-asserted-by":"publisher","DOI":"10.1002\/(sici)1097-0142(20000101)88:1<50::aid-cncr8>3.0.co;2-i"},{"key":"B37","unstructured":"Stroescu C, Dragnea A, Ivanov B, Pechianu C, Herlea V, Sgarbura O, Popescu A, Popescu I. Expression of p53, Bcl-2, VEGF, Ki67 and PCNA and prognostic significance in hepatocellular carcinoma. J Gastrointestin Liver Dis 2008; 17: 411-417"},{"key":"B38","doi-asserted-by":"publisher","DOI":"10.1007\/s12253-008-9031-2"},{"key":"B39","doi-asserted-by":"publisher","DOI":"10.1016\/j.cbi.2019.108891"},{"key":"B40","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-018-1389-x"},{"key":"B41","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e07-12-1215"},{"key":"B42","doi-asserted-by":"publisher","DOI":"10.7150\/jca.26578"},{"key":"B43","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/19.9.2024"},{"key":"B44","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015730"},{"key":"B45","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-012-0379-5"},{"key":"B46","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0676.2001.021002089.x"},{"key":"B47","doi-asserted-by":"publisher","DOI":"10.1016\/s0955-0674(96)80081-0"},{"key":"B48","doi-asserted-by":"publisher","DOI":"10.5808\/GI.2014.12.4.156"},{"key":"B49","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-0762"},{"key":"B50","doi-asserted-by":"publisher","DOI":"10.3109\/10715761003692503"},{"key":"B51","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2012.01.024"},{"key":"B52","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-13-0080"},{"key":"B53","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxrep.2014.11.015"},{"key":"B54","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/23.11.1781"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i45\/7131.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,4]],"date-time":"2020-12-04T04:32:04Z","timestamp":1607056324000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v26\/i45\/7131.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,12,7]]},"references-count":54,"journal-issue":{"issue":"45"},"URL":"https:\/\/doi.org\/10.3748\/wjg.v26.i45.7131","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2020,12,7]]}}}