{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,13]],"date-time":"2025-05-13T04:11:39Z","timestamp":1747109499380},"reference-count":12,"publisher":"Baishideng Publishing Group Inc.","issue":"26","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastroenterol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Multiple endocrine neoplasias (MENs) are a group of hereditary diseases involving multiple endocrine glands, and their prevalence is low. MEN type 1 (MEN1) has diverse clinical manifestations, mainly involving the parathyroid glands, gastrointestinal tract, pancreas and pituitary gland, making it easy to miss the clinical diagnosis.<\/jats:p>\n          <jats:p>CASE SUMMARY<\/jats:p>\n          <jats:p>We present the case of a patient in whom MEN1 was detected early. A middle-aged male with recurrent abdominal pain and diarrhea was admitted to the hospital. Blood tests at admission revealed hypercalcemia and hypophosphatemia, and emission computed tomography of the parathyroid glands revealed a hyperfunctioning parathyroid lesion. Gastroscopy findings suggested a duodenal bulge and ulceration. Ultrasound endoscopy revealed a hypoechoic lesion in the duodenal bulb. Further blood tests revealed elevated levels of serum gastrin. Surgery was performed, and pathological analysis of the surgical specimens revealed a parathyroid adenoma after parathyroidectomy and a neuroendocrine tumor after duodenal bulbectomy. The time from onset to the definitive diagnosis of MEN1 was only approximately 1 year.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>For patients who present with gastrointestinal symptoms accompanied by hypercalcemia and hypophosphatemia, clinicians need to be alert to the possibility of MEN1.<\/jats:p>","DOI":"10.3748\/wjg.v30.i26.3247","type":"journal-article","created":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T08:59:42Z","timestamp":1720515582000},"page":"3247-3252","source":"Crossref","is-referenced-by-count":4,"title":["Early detection of multiple endocrine neoplasia type 1: A case report"],"prefix":"10.3748","volume":"30","author":[{"given":"Jie-Hao","family":"Yuan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su","family":"Luo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ding-Guo","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-Sheng","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2024,7,14]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lpm.2018.03.005"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-021-00468-3"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2013-0369"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2021.04.011"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1159\/000443171"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1007\/s11894-004-0067-5"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2012-1230"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.3389\/fendo.2020.557050"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-21-0073"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.soc.2015.06.008"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1136\/jmg.40.5.e72"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.1186\/s12916-016-0708-1"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v30\/i26\/3247.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v30\/i26\/3247.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,7,9]],"date-time":"2024-07-09T09:00:16Z","timestamp":1720515616000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v30\/i26\/3247.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,7,14]]},"references-count":12,"journal-issue":{"issue":"26"},"URL":"https:\/\/doi.org\/10.3748\/wjg.v30.i26.3247","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2024,7,14]]}}}