{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T15:24:28Z","timestamp":1791991468778,"version":"4.4.0"},"reference-count":29,"publisher":"Baishideng Publishing Group Inc.","issue":"27","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastroenterol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Endoscopic rubber band ligation (ERBL) is a nonsurgical technique for the treatment of symptomatic internal hemorrhoids but is limited by recurrence and post-procedural pain.<\/jats:p>\n          <jats:p>AIM<\/jats:p>\n          <jats:p>To evaluate satisfaction, long-term recurrence, and post-procedural pain in managing internal hemorrhoids using a combination of polidocanol foam sclerotherapy and ERBL.<\/jats:p>\n          <jats:p>METHODS<\/jats:p>\n          <jats:p>This was a prospective, multicenter, randomized study. A total of 195 consecutive patients diagnosed with grade II-III internal hemorrhoids were enrolled from four tertiary hospitals and randomly divided into a cap-assisted endoscopic polidocanol foam sclerobanding (EFSB) or an ERBL group. All patients were followed-up for 12 months. Symptom-based severity and post-procedural pain were assessed using a hemorrhoid severity score (HSS) and a visual analog scale (VAS). Continuous variables were reported as medians and interquartile range.<\/jats:p>\n          <jats:p>RESULTS<\/jats:p>\n          <jats:p>One hundred and ninety-five patients were enrolled, with 98 in the EFSB group. HSS was lower in the EFSB group than in the ERBL group at 8 weeks [4.0 (3.0-5.0) vs  5.0 (4.0-6.0), P  = 0.003] and 12-month [2.0 (1.0-3.0) vs  3.0 (2.0-3.0), P  &lt; 0.001] of follow-up. The prolapse recurrence rate was lower in the EFSB group at 12 months (11.2% vs  21.6%, P  = 0.038). Multiple linear regression analysis demonstrated that EFSB treatment [B = -0.915, 95% confidence interval (CI): \u22121.301 to \u22120.530, P  = 0.001] and rubber band number (B = 0.843, 95%CI: 0.595-1.092, P  &lt; 0.001) were negatively and independently associated with the VAS score 24 hours post-procedure. The median VAS was lower in the EFSB group than in the ERBL [2.0 (1.0-3.0) vs  3.0 (2.0-4.0), P  &lt; 0.001].<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Cap-assisted EFSB provided long-term satisfaction and effective relief from the recurrence of prolapse and pain 24 hours post-procedure.<\/jats:p>","DOI":"10.3748\/wjg.v30.i27.3326","type":"journal-article","created":{"date-parts":[[2024,7,11]],"date-time":"2024-07-11T07:24:52Z","timestamp":1720682692000},"page":"3326-3335","source":"Crossref","is-referenced-by-count":25,"title":["Endoscopic polidocanol foam sclerobanding for the treatment of grade II-III internal hemorrhoids: A prospective, multi-center, randomized 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