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The management focuses on controlling the perianal sepsis and treating luminal CD. Biologics are crucial to the treatment approach, and results have been encouraging. The surgery focuses on controlling the sepsis, with more definitive treatments being fistula surgery, fecal diversion, and proctectomy as the last resort. This manuscript briefly describes the burden of CD, the challenges posed by perianal CD, and the role of different treatment modalities from colorectal surgeon\u2019s perspective.<\/jats:p>","DOI":"10.3748\/wjg.v30.i44.4745","type":"journal-article","created":{"date-parts":[[2024,11,11]],"date-time":"2024-11-11T03:07:26Z","timestamp":1731294446000},"page":"4745-4753","source":"Crossref","is-referenced-by-count":5,"title":["Navigating the complexities of perianal Crohn\u2019s disease: Diagnostic strategies, treatment approaches, and future perspectives"],"prefix":"10.3748","volume":"30","author":[{"given":"Jai P","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maryam","family":"Aleissa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ernesto R","family":"Drelichman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijay K","family":"Mittal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jasneet S","family":"Bhullar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2024,11,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-193811000-00007"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.15585\/mmwr.mm6542a3"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1136\/gut.21.6.525"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1016\/j.gastro.2003.08.025"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2002.32362"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1016\/s0016-5085(98)70420-2"},{"key":"B7","unstructured":"Geltzeiler CB, Wieghard N, Tsikitis VL. 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