{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,5]],"date-time":"2026-02-05T07:53:46Z","timestamp":1770278026280,"version":"3.49.0"},"reference-count":19,"publisher":"Baishideng Publishing Group Inc.","issue":"8","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastroenterol"],"abstract":"<jats:p>BACKGROUND<\/jats:p>\n          <jats:p>Cronkhite-Canada syndrome (CCS) is a rare, noninherited disease characterized by gastrointestinal polyposis with diarrhea and ectodermal abnormalities. CCS polyps are distributed through the whole digestive tract, and they are common in the stomach and colon but very uncommon in the esophagus.<\/jats:p>\n          <jats:p>CASE SUMMARY<\/jats:p>\n          <jats:p>Here, we present a case of a 63-year-old man with skin hyperpigmentation accompanied by diarrhea, alopecia, and loss of his fingernails. Laboratory data indicated anemia, hypoalbuminemia, hypocalcemia, hypokalemia, and positive fecal occult blood. Endoscopy showed numerous polyps scattered throughout the digestive tract, including the esophagus. He was treated with nutritional support and glucocorticoids with remission of his symptoms.<\/jats:p>\n          <jats:p>CONCLUSION<\/jats:p>\n          <jats:p>Comprehensive treatment led by hormonal therapy can result in partial or full remission of clinical symptoms. Treatment should be individualized for each patient according to their therapy response. Surveillance endoscopy is necessary for assessing mucosal disease activity and detecting malignant transformation.<\/jats:p>","DOI":"10.3748\/wjg.v30.i8.984","type":"journal-article","created":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T06:51:11Z","timestamp":1708930271000},"page":"984-990","source":"Crossref","is-referenced-by-count":3,"title":["Cronkhite-Canada syndrome with esophagus involvement and six-year follow-up: A case report"],"prefix":"10.3748","volume":"30","author":[{"given":"Yu-Chen","family":"Tang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"2060","published-online":{"date-parts":[[2024,2,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2010.112"},{"key":"B2","unstructured":"Goto A. Cronkhite-Canada syndrome: epidemiological study of 110 cases reported in Japan. Nihon Geka Hokan 1995; 64: 3-14"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1136\/jclinpath-2014-202488"},{"key":"B4","doi-asserted-by":"crossref","unstructured":"Daniel ES, Ludwig SL, Lewin KJ, Ruprecht RM, Rajacich GM, Schwabe AD. The Cronkhite-Canada Syndrome. An analysis of clinical and pathologic features and therapy in 55 patients. Medicine (Baltimore) 1982; 61: 293-309","DOI":"10.1097\/00005792-198209000-00002"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.4166\/kjg.2018.71.4.239"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2017-223527"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1159\/000076560"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-016-0436-1"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.1016\/j.amsu.2022.104090"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1093\/gastro\/goaa058"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i23.7518"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.4318\/tjg.2013.0527"},{"key":"B13","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0000000000000718"},{"key":"B14","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2021.10823"},{"key":"B15","unstructured":"McGarrity TJ, Amos CI, Baker MJ.   Peutz-Jeghers Syndrome. 2001 Feb 23. In: GeneReviews\u00ae [Internet]. Seattle (WA): University of Washington, Seattle; 1993-2024"},{"key":"B16","doi-asserted-by":"publisher","DOI":"10.1007\/s10620-011-1874-9"},{"key":"B17","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-015-1107-7"},{"key":"B18","doi-asserted-by":"publisher","DOI":"10.1159\/000514354"},{"key":"B19","doi-asserted-by":"publisher","DOI":"10.14309\/ctg.0000000000000167"}],"container-title":["World Journal of Gastroenterology"],"original-title":[],"link":[{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v30\/i8\/984.htm","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v30\/i8\/984.htm","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,2,26]],"date-time":"2024-02-26T06:52:33Z","timestamp":1708930353000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.wjgnet.com\/1007-9327\/full\/v30\/i8\/984.htm"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,2,28]]},"references-count":19,"journal-issue":{"issue":"8"},"URL":"https:\/\/doi.org\/10.3748\/wjg.v30.i8.984","relation":{},"ISSN":["1007-9327"],"issn-type":[{"value":"1007-9327","type":"print"}],"subject":[],"published":{"date-parts":[[2024,2,28]]}}}