{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T06:58:59Z","timestamp":1784617139897,"version":"3.55.0"},"reference-count":29,"publisher":"Baishideng Publishing Group Inc.","issue":"36","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["World J Gastroenterol"],"abstract":"BACKGROUND<\/jats:p>\n Rectal neuroendocrine tumors (NETs) smaller than 10 mm and well-differentiated tumors are generally considered to have a low risk of lymph node and distant metastasis, making them suitable for endoscopic resection. In contrast, tumors \u2265 20 mm in size typically require surgical resection. However, the optimal management of intermediate-sized (10-15 mm) rectal NETs remains controversial.<\/jats:p>\n AIM<\/jats:p>\n To compare the clinical outcomes of endoscopic resection of rectal NETs < 1 cm and those 1-1.5 cm in size.<\/jats:p>\n METHODS<\/jats:p>\n A retrospective study was conducted on 1056 patients with rectal NETs treated at the Samsung Medical Center between January 2005 and June 2021. After propensity score matching (1:10) for age, sex, and type of endoscopic resection, 225 patients with tumors < 1 cm in size and 27 patients with tumors 1-1.5 cm in size were analyzed.<\/jats:p>\n RESULTS<\/jats:p>\n Surgical resection was more frequent in the 1-1.5 cm group (37.2%) than in the < 1 cm group (10.7%) (P < 0.01). Endoscopic submucosal dissection was also more commonly performed in the 1-1.5 cm group (48.1% vs 18.5%, P < 0.01). Negative resection margins were achieved in 97.2% of the patients, with no significant difference between the groups (P = 0.22). No lymphovascular invasion was observed. During a median follow-up of 54 months, no recurrence occurred in the 1-1.5 cm group, while one case of metachronous recurrence was noted in the < 1 cm group (P = 1.00). There was no significant difference in recurrence-free survival (P = 0.48).<\/jats:p>\n CONCLUSION<\/jats:p>\n Endoscopic resection of 1-1.5 cm grade 1 rectal NETs yielded comparable outcomes to those < 1 cm in size, suggesting its feasibility as a treatment.<\/jats:p>","DOI":"10.3748\/wjg.v31.i36.109846","type":"journal-article","created":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T09:55:08Z","timestamp":1758189308000},"source":"Crossref","is-referenced-by-count":5,"title":["Long-term outcomes of endoscopic resection of 1-1.5 cm sized grade 1 rectal neuroendocrine tumor: A retrospective study"],"prefix":"10.3748","volume":"31","author":[{"given":"Minjee","family":"Kim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuwon","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ji Eun","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sung Noh","family":"Hong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dong Kyung","family":"Chang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young-Ho","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eun Ran","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"2060","published-online":{"date-parts":[[2025,9,28]]},"reference":[{"key":"B1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics11050771"},{"key":"B2","doi-asserted-by":"publisher","DOI":"10.1159\/000242109"},{"key":"B3","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2017.0589"},{"key":"B4","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-86839-2"},{"key":"B5","doi-asserted-by":"publisher","DOI":"10.3892\/mco.2017.1326"},{"key":"B6","doi-asserted-by":"publisher","DOI":"10.1159\/000335594"},{"key":"B7","doi-asserted-by":"publisher","DOI":"10.1055\/s-2004-814248"},{"key":"B8","doi-asserted-by":"publisher","DOI":"10.1159\/000443166"},{"key":"B9","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v12.i25.4026"},{"key":"B10","doi-asserted-by":"publisher","DOI":"10.1016\/j.gie.2007.02.032"},{"key":"B11","doi-asserted-by":"publisher","DOI":"10.1245\/s10434-023-14829-x"},{"key":"B12","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2024.1383047"},{"key":"B13","unstructured":"Mani S, Modlin IM, Ballantyne G, Ahlman H, West B. 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